Prof. Ahcène Boumendjel recognized for his expertise in natural products and innovative drug design. He leads research within the Laboratoire Radiopharmaceutiques Biocliniques in the Faculty of Medicine, focusing on transforming plant-derived compounds into promising therapeutic candidates targeting cancer, viral infections, and bacterial diseases. A highly accomplished medicinal chemist with extensive expertise in natural products and small-molecule drug discovery, known for advancing therapeutic development across oncology, antiviral, and antibacterial applications. Their research integrates organic synthesis, phytochemistry, and hit-to-lead optimization to convert bioactive natural compounds into potent and selective drug candidates. Serving in senior academic and research leadership roles, they oversee medicinal chemistry programs, guide multidisciplinary teams, and contribute to curriculum development in pharmaceutical sciences. Their international research experience has strengthened collaborations in translational chemistry and innovative molecular design. With 5,897 citations by 4,277 documents, an output of 154 scientific publications, and an h-index of 45, their work reflects significant global influence and sustained scientific impact. In addition to multiple patents and invited conference presentations, they have supervised numerous doctoral, postdoctoral, and international researchers, fostering talent in advanced chemical and pharmaceutical research. Their ongoing contributions continue to bridge fundamental chemical discovery with therapeutic innovation, supporting progress in healthcare through the exploration, optimization, and development of bioactive natural product scaffolds.
Profiles: Scopus | ORCID
Featured Publications
New players from the old chalcone scaffold: Synthesis, identification, and characterization of new potent ABCG2 inhibitors. European Journal of Medicinal Chemistry.
Garcinia kola nuts: A molecular cocktail for skin care. Molecules.
Aurones as new modulators of hypoxia inducible factor-1 (HIF-1) to prevent cardiac cell death. Results in Chemistry.
Assembly of detergents with highly branched dicarboxylate clamps for membrane protein studies. ChemistryOpen.
Photoisomerization of azobenzene-extended charybdotoxin for the optical control of Kv1.2 potassium channel activity. Angewandte Chemie International Edition.
Ligand-based drug discovery leveraging state-of-the-art machine learning methodologies exemplified by Cdr1 inhibitor prediction. Journal of Chemical Information and Modeling.