Associate Professor, at Tehran University of Medical Sciences, Iran.
Dr. Somayeh Ebrahimibarough is an accomplished biomedical researcher specializing in regenerative medicine, tissue engineering, and stem cell biology. She holds a Ph.D. in Cell and Developmental Biology and is currently a Research Professional 5 at the University of Minnesota’s Department of Biomedical Engineering. Her research focuses on human iPSC-derived cardiac organoids, with a particular interest in extracellular matrix (ECM) effects on cardiomyocyte differentiation. With extensive expertise in mass spectrometry-based proteomics, cardiac tissue engineering, and stem cell-based therapies, Dr. Ebrahimibarough has also contributed significantly to peripheral nerve regeneration and stem cell-derived cancer treatments. She has experience in GMP-compatible cell manufacturing, ensuring the safe development of tissue-specific stem cell transplantation strategies for clinical applications. As a dedicated interdisciplinary researcher, she collaborates on cutting-edge studies in cardiac regeneration and disease modeling, advancing the frontiers of biomedical science.
Professional Profile
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🎓 Education
Dr. Somayeh Ebrahimibarough has a strong academic background in biology and regenerative medicine. She earned her Ph.D. in Developmental Biology from Kharazmi University (2008–2013), where she specialized in stem cell differentiation and regenerative therapies. Before that, she completed her M.S. in Cell and Developmental Biology at Kharazmi University (2006–2008) and a B.S. in Biology from Mohaghegh Ardabili University (2002–2005). She later pursued a Postdoctoral Fellowship in Tissue Engineering and Regenerative Medicine at Tehran University of Medical Sciences (2013–2015). Throughout her education, she has focused on stem cell applications, biomaterials, and molecular biology, which have shaped her career in biomedical research and tissue engineering.
💼 Experience
Dr. Ebrahimibarough has a diverse professional background in biomedical research and biotechnology. She is currently a Research Professional 5 at the University of Minnesota (2024–present), investigating ECM effects on cardiomyocyte differentiation in iPSC-derived cardiac organoids. Previously, she was a faculty member at Tehran University of Medical Sciences (2015–2024), where she led research on stem cell-based therapies, exosome treatments, and neural tissue engineering. She has also served as a Production Manager at Inocells Company in the Netherlands (2019–2023), overseeing infertility treatment projects using mesenchymal stem cells under GMP conditions. Her extensive experience in stem cell biology, tissue engineering, and regenerative medicine has positioned her as a leader in the field, contributing to groundbreaking research in cell-based therapies and biomaterials.
🔬 Research Interests
Dr. Ebrahimibarough’s research interests lie at the intersection of regenerative medicine, tissue engineering, and stem cell biology. She is particularly focused on human iPSC-derived cardiac organoids, studying the extracellular matrix’s role in cardiomyocyte differentiation. Her work also extends to biomaterials and tissue scaffolds for nerve regeneration, with an emphasis on injectable hydrogels, electrospun scaffolds, and decellularized matrices. Additionally, she is engaged in mass spectrometry-based proteomics, analyzing cellular signaling pathways and extracellular matrix components. Dr. Ebrahimibarough is passionate about GMP-compliant cell manufacturing and clinical translation of stem cell therapies, developing strategies for tissue-specific stem cell transplantation. Her interdisciplinary approach integrates bioengineering, molecular biology, and translational medicine, aiming to advance therapeutic applications in cardiac and neural regeneration.
🏆 Awards & Recognitions
Dr. Ebrahimibarough has received several prestigious awards for her contributions to biomedical research:
- One-Year Salary Grant for Postdoctoral Research (2014) – Awarded by the Iran National Science Foundation (INSF) for excellence in tissue engineering research.
- Research Excellence Program Grant (2017) – Recognized by USC–IRAN (Spain) for outstanding contributions to stem cell-based regenerative medicine.
- Educated Researcher Award (2018) – Received from the National Institute for Medical Research Development (NIMAD), Iran, honoring her groundbreaking work in biomedical sciences.
Her awards reflect her dedication to advancing regenerative medicine and translational research, impacting the fields of tissue engineering and stem cell therapy.
📚 Top Noted Publications
Dr. Ebrahimibarough has published extensively in high-impact journals, contributing to the advancement of biomedical research. Here are some of her key publications:
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Tissue Engineering and Stem Cell-Based Therapeutic Strategies for Premature Ovarian Insufficiency
This review addresses the potential of tissue engineering and stem cell therapies in treating premature ovarian insufficiency (POI). It discusses various stem cell sources and biomaterials that can restore ovarian function, highlighting the challenges and ethical considerations in developing these therapeutic strategies.
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Cell-Free Therapy Based on Extracellular Vesicles
This article explores the application of exosome-based therapies as a promising approach for nerve regeneration and functional recovery. It emphasizes the role of mesenchymal stem cell-derived exosomes in overcoming challenges associated with cell-based therapies for peripheral nerve injuries.
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Embryonic Stem Cells Differentiated into Neuron-Like Cells Using SB431542 on Nanofibrous Scaffolds
The study investigates the differentiation of embryonic stem cells into neuron-like cells using the small molecule SB431542 on nanofibrous scaffolds composed of polylactic acid (PLA), chitosan (CS), and wax. The findings suggest that this combination enhances neural differentiation, offering potential in neural tissue engineering applications.
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Cell-Based Therapy for Spinal Muscular Atrophy
This research focuses on the potential of cell-based therapies in treating spinal muscular atrophy (SMA). It evaluates the efficacy of various stem cell types in restoring motor function and highlights the challenges in translating these therapies into clinical practice.
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Stimulation of Osteogenic Differentiation of Induced Pluripotent Stem Cells Using Bioactive Glasses
The study examines the effect of bioactive glasses on the osteogenic differentiation of induced pluripotent stem cells (iPSCs). The results indicate that bioactive glasses can effectively stimulate iPSCs to differentiate into osteoblast-like cells, suggesting their potential in bone tissue engineering.
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Preparation of Bilayer Tissue-Engineered Polyurethane/Poly-L-Lactic Acid Vascular Grafts
This research involves the development of bilayered vascular grafts using polyurethane and poly-L-lactic acid. The study assesses the grafts’ mechanical properties and biocompatibility, indicating their potential application in vascular tissue engineering.
Conclusion
Dr. Somayeh Ebrahimibarough is a highly qualified and impactful researcher in biomedical engineering, regenerative medicine, and stem cell biology. Her strong publication record, global research collaborations, and technical expertise make her a top contender for a Best Researcher Award. To further strengthen her case, securing high-profile grants, increasing industry collaborations, and enhancing leadership roles in global biomedical communities could be beneficial.