Mr.Akshay Patel | Tumour immunology | Best Researcher Award 

Clinical Lecturer University of Birmingham United Kingdom

Suitability of Akshay Jatin Patel for the Best Researcher Award

Strengths for the Award:

1. Extensive Education and Training:
   • Akshay holds an MBBS from St. George’s, University of London, and an MA(Cantab) from the University of Cambridge, with a first-class mark in pharmacology. He also completed a PhD in the immunobiology of B lymphocytes in non-small cell lung cancer at the University of Birmingham.
   • His education is complemented by specialized post-graduate training, including a Senior Fellowship in Robotic Thoracic Surgery and a Fellowship of the Royal College of Surgeons.
2. Research Experience and Contributions:
   • Akshay has been involved in significant research projects, such as the TRACERx study, and has developed multi-disciplinary research streams at the University of Birmingham.
   • His research has been recognized with several funding awards, including from Cancer Research UK, totaling over £100,000.
3. Publications and Academic Impact:
   • He has authored numerous peer-reviewed papers in high-impact journals, including Nature and Cancer Research Communications, with topics ranging from immune profiles in cancer to biomarkers for early-stage NSCLC.
   • His work on B-cell profiles in melanoma and the T-cell receptor repertoire in lung cancer highlights his contributions to understanding cancer immunobiology.
4. Professional and Academic Leadership:
   • Akshay has held various leadership positions, including Thoracic Surgery Specialist Registrar and Associate Surgical Specialty Lead for Thoracic Surgery Research at RCS England.
   • He has been actively involved in organizing national research meetings and contributing to task forces and steering committees, which demonstrates his leadership in the field.
5. Teaching and Mentorship:
   • He has extensive teaching experience at both undergraduate and postgraduate levels, including digital teaching initiatives and running workshops and conferences for medical students and junior doctors.

Areas of Improvement:

1. Broader Collaborative Networks:
   • While Akshay has strong collaborations within the UK and some international exposure, expanding his collaborative network globally could enhance the impact and reach of his research.
2. Focus on Diverse Research Topics:
   • Diversifying his research to include a broader range of topics within thoracic surgery and oncology might provide a more comprehensive understanding of the field and open new avenues for innovation.
3. Increased Public and Policy Engagement:
   • Engaging more with public health policy and advocacy could help translate his research findings into clinical practice and influence healthcare policies on a broader scale.

Conclusion:

Akshay Jatin Patel demonstrates exceptional qualifications for the Best Researcher Award through his robust academic background, significant research contributions, numerous publications, and leadership roles in the field of thoracic surgery and cancer immunobiology. His continuous efforts in teaching and mentorship further emphasize his commitment to advancing medical science and education. Addressing the suggested areas of improvement could further amplify his impact, making him a strong candidate for the award.

Dr. Akshay Jatin Patel is an accomplished cardiothoracic surgeon with a profound dedication to advancing thoracic surgery and cancer research. With an impressive educational background and extensive clinical training, Dr. Patel has made significant contributions to the field through his innovative research, publications, and leadership roles. His expertise spans robotic thoracic surgery, immunobiology, and lung cancer, making him a prominent figure in the medical community.

Profile

ORCiD

Education 🎓

Dr. Patel’s educational journey began at Loughborough Grammar Boy’s School, followed by a BA Hons and MA(Cantab) from Fitzwilliam College, University of Cambridge. He earned his MBBS from St. George’s, University of London, graduating with merit in Clinical Sciences. His postgraduate training includes a Senior Fellowship in Robotic Thoracic Surgery at Guy’s and St. Thomas’ NHS Foundation Trust, and a PhD from the University of Birmingham, where his research focused on the immunobiology of B lymphocytes in non-small cell lung cancer.

Experience 🏥

Dr. Patel’s extensive experience includes his role as a Clinical Lecturer at the Institute of Immunology and Immunotherapy, University of Birmingham, and as a Specialist Registrar in Thoracic Surgery at University Hospitals of Birmingham. He has completed numerous fellowships, including a mini-fellowship in congenital heart surgery at the Royal Children’s Hospital in Melbourne and a clinical clerkship at Narayana Hrudayalaya Institute of Cardiac Sciences in Bangalore. His leadership positions include Associate Surgical Specialty Lead for Thoracic Surgery Research at RCS England.

Research Interests 🔬

Dr. Patel’s research interests lie in the intersection of thoracic surgery and cancer immunology. He focuses on the immunobiology of B lymphocytes in non-small cell lung cancer, translational science, and the development of predictive biomarkers for early-stage NSCLC. His work aims to enhance the understanding of cancer metastasis and improve therapeutic outcomes for lung cancer patients through innovative research and clinical trials.

Awards 🏆

Dr. Patel has received numerous awards for his contributions to medical science, including the 2023 McCormack Gold Medal for outstanding performance in the FRCS(CTh) examination, several Cancer Research UK awards, and the Research Development Surgeon Award from the University of Birmingham. These accolades underscore his commitment to excellence and innovation in thoracic surgery and cancer research.

Publications 📚

Dr. Patel has published extensively in high-impact journals. Here are some key publications:

1. Pickles OJ, Wanigasooriya K, et al. (2023). Major histocompatibility complex-class II is induced by Interferon-gamma and follows three distinct patterns of expression in colorectal cancer organoids. Cancer Res Commun. Cancer Res Commun. Cited by 12 articles.
2. Willsmore ZN, Crescioli S, et al. (2023). Advanced melanoma is associated with distinct circulating B-cell profiles enriched with immunoregulatory and autoreactive feature. Br J Dermatol. Br J Dermatol. Cited by 8 articles.
3. Patel AJ, Khan N, et al. (2023). Deep immune B and plasma cell repertoire in non-small cell lung cancer. Front Immunol. Front Immunol. Cited by 15 articles.
4. Abbosh C, Frankell AM, et al. (2023). Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA. Nature. Nature. Cited by 22 articles.
5. Patel AJ, Willsmore Z, et al. (2022). Regulatory B cell repertoire defects predispose lung cancer patients to immune-related toxicity following checkpoint blockade. Nat Commun. Nat Commun. Cited by 18 articles.
6. Wu Y, Biswas D, et al. (2022). A local human Vδ1 T cell population is associated with survival in non-small-cell lung cancer. Nat Cancer. Nat Cancer. Cited by 25 articles.
7. Patel AJ, Tan TM, et al. (2022). A highly predictive autoantibody-based biomarker panel for prognosis in early-stage NSCLC with potential therapeutic implications. Br J Cancer. Br J Cancer. Cited by 14 articles.
8. Bentham R, Litchfield K, et al. (2021). Using DNA sequencing data to quantify T cell fraction and therapy response. Nature. Nature. Cited by 30 articles.
9. AbdulJabbar K, Raza SEA, et al. (2020). Geospatial immune variability illuminates differential evolution of lung adenocarcinoma. Nat Med. Nat Med. Cited by 28 articles.
10. Lopez S, Lim EL, et al. (2020). Interplay between whole genome doubling and the accumulation of deleterious alterations in cancer evolution. Nat Genetics. Nat Genetics. Cited by 35 articles.