Manuela Cappelletti | Immunology | Industry Impact Award

Mrs. Manuela Cappelletti | Immunology | Industry Impact Award 

Senior lab biologist | TAKIS srl | Italy

Mrs. Manuela Cappelletti is an accomplished Italian Senior Laboratory Biologist with extensive experience in molecular biology, immunology, and preclinical biotechnology. She has played a key role at Takis Srl in Rome, contributing to research in monoclonal antibody generation and vaccine development. Previously, she held senior research positions at IRBM Merck Research Laboratories and RTC Research Toxicology Center, where she developed expertise in molecular cloning, cell biology, and animal experimentation. At Takis, she oversees hybridoma generation, antibody subcloning, and large-scale antibody production, ensuring high standards of biosafety and reproducibility. Her work has advanced innovative immunotherapy and vaccine platforms, including contributions to DNA-based vaccine research. With 23 scientific publications, 1,724 citations by 1,545 documents, and an h-index of 18, her research has significantly impacted the fields of antibody science and translational immunology. Renowned for her precision and leadership in laboratory innovation, Manuela continues to bridge fundamental science with applied biomedical research, fostering progress in immunotherapy and infectious disease solutions.

Profile: Scopus | ORCID

Featured Publications

Cappelletti, M., et al. (n.d.). Isolation and characterization of neutralizing monoclonal antibodies against SARS-CoV-2 spike protein. Antibodies (Basel). Cited by 12.

Cappelletti, M., et al. (n.d.). COVID-eVax: An electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD. Molecular Therapy, 30(4). Cited by 58.

Cappelletti, M., et al. (n.d.). COVID-eVax DNA vaccine elicits protective immune responses in animal models. bioRxiv. Cited by 72.

Cappelletti, M., et al. (n.d.). Gene electro-transfer improves transduction by modifying the fate of intramuscular DNA. Journal of Gene Medicine, 5(3). Cited by 130.

Cappelletti, M., et al. (n.d.). C/EBP beta and acute phase gene regulation in liver cells. Cell Death and Differentiation, 3(2). Cited by 45.

 

Stefania Dentice | immunomodulation | Best Researcher Award

Dr. Stefania Dentice | immunomodulation | Best Researcher Award 

Researcher, at CERELA, Argentina.

Stefania Dentice Maidana is a dedicated biochemist and entrepreneur with over seven years of experience in food and pharmaceutical research, particularly in probiotics. As the Head of the Clinical Bacteriology Department at CACE in Tucumán, Argentina, she leads efforts to improve public health through microbiological innovations. Stefania’s passion for probiotics extends beyond her research role, as she co-founded Inmunofit, a kefir-based beverage startup promoting health through fermented foods. She is also an educator, teaching bacteriology and mentoring future scientists. Her work emphasizes the connection between gut health and probiotics in enhancing human well-being.

Profile

Scopus

Education

🎓 Stefania holds a PhD in Biological Science, with a focus on biochemistry and microbiology. She completed her doctoral thesis on the functionalization of chia flour with nutraceutical-producing lactic acid bacteria at CERELA, under the direction of Graciela Vignolo and Graciela Savoy. Her education also includes a postdoctoral fellowship at CERELA, where she studied respiratory commensal bacteria as probiotics. Stefania further expanded her expertise through IICA Canada’s Research and Internship Assistance Program at the University of Alberta, where she conducted microbial and biochemical research on chia sourdoughs.

Experience

👩‍🏫 Stefania’s professional experience is vast and includes her current role as the Head of the Clinical Bacteriology Department at a high-complexity clinical analysis center, CACE, in Tucumán. She is also an entrepreneur, co-founding Inmunofit, a kefir-based beverage company promoting gut health. In academia, Stefania teaches practical bacteriology applications at the National University of Tucumán, contributing to both education and scientific discovery. She has also mentored students in microbiology, fostering future scientists’ growth. Her work combines applied research, education, and entrepreneurial endeavors.

Research Interest

🔬 Stefania’s research is focused on probiotics, fermented foods, and their health benefits, especially in the maintenance of a healthy intestinal microbiota. She is passionate about studying probiotic bacteria, such as lactic acid bacteria, to develop nutraceutical food products that promote overall health. Her work also extends to characterizing bacterial pathogens, such as hypermucoviscous carbapenem-resistant Klebsiella pneumoniae, and studying probiotic respiratory commensals. Stefania is driven to bring scientific advancements in microbiology to the public, ensuring that her research contributes to societal health.

Awards

🏆 Stefania has received numerous prestigious fellowships and scholarships throughout her career. These include a postdoctoral fellowship at CERELA, where she worked on probiotics and immunity, and IICA Canada’s Research and Internship Assistance Program, where she conducted research on chia sourdoughs. She was also awarded the CONICET Postgraduate Scholarship for her doctoral thesis on chia flour functionalization, along with the CIUNT Student Scholarship, which allowed her to further her studies in molecular pathology. Her accolades reflect her commitment to impactful scientific research.

Publications 

📄 Stefania has published numerous research papers that showcase her expertise in probiotics, pathogenic bacteria, and fermented foods. Below are some key publications:

  • 023: “Hypermucoviscous Carbapenem-Resistant Klebsiella pneumoniae ST25 Infect Human Intestinal Epithelial Cells and Induce Moderate Inflammation.” International Journal of Molecular Sciences, 24(10), 8804. Link. Cited by 3 articles.
  • 2022: “Respiratory Commensal Bacteria Increase Protection against Hypermucoviscous Carbapenem-Resistant Klebsiella pneumoniae ST25 Infection.” Pathogens, 11(9), 1063. Link. Cited by 5 articles.
  • 2022: “Genomic and Immunological Characterization of Hypermucoviscous Carbapenem-Resistant Klebsiella pneumoniae ST25 Isolates from Northwest Argentina.” International Journal of Molecular Sciences, 23(13), 7361. Link. Cited by 8 articles.
  • 2021: “Draft Genome Sequences of Two Hypermucoviscous Carbapenem-Resistant ST25 Klebsiella pneumoniae Strains Causing Respiratory and Systemic Infections.” Journal of Global Antimicrobial Resistance, 27, 66-71. Link. Cited by 12 articles.
  • 2021: “Characterization of Weissella viridescens UCO-SMC3 as a Potential Probiotic for the Skin: Its Beneficial Role in the Pathogenesis of Acne Vulgaris.” Journal of Microorganisms, 9(7), 1486. Link. Cited by 4 articles.
  • 2020: “Development of Gluten-Free Breads Started with Chia and Flaxseed Sourdoughs Fermented by Selected Lactic Acid Bacteria.” LWT – Food Sciences and Technology, 109, 189. Link. Cited by 9 articles.
  • 2019: “Biodiversity and Technological Functional Potential of Lactic Acid Bacteria from Spontaneously Fermented Chia Sourdough.” International Journal of Food Microbiology, 316, 108425. Link. Cited by 11 articles.

Conclusion

Stefania Dentice Maidana exemplifies the qualities of an outstanding researcher deserving of the Best Researcher Award. Her extensive experience in biochemistry, proven track record of innovative research, and entrepreneurial spirit position her as a leader in promoting health through probiotics and fermented foods. By addressing areas for improvement, she can further amplify her impact and continue to contribute significantly to her field. Her dedication to education and community engagement, combined with her research accomplishments, make her a worthy candidate for this esteemed recognition.