Prof. Georges Nemer | Molecular Biology | Editorial Board Member
Professor | Hamad Bin Khalifa University | Qatar
Dr. Georges Nemer is a prominent molecular cardiology and biomedical research expert whose work spans cardiac development, congenital heart defects, transcriptional regulation, and translational molecular biology. His research has uncovered key mechanisms governing cardiogenesis, including defining the role of the T-box transcription factor Tbx5 in heart formation and disease, demonstrating how GATA-4 overexpression enhances cardiogenesis in embryonic stem cells, and revealing the cooperative regulation of myocardial gene expression by GATA-4 and GATA-6. Dr. Nemer has also contributed to clinical genetics through the identification of novel GATA4 mutations associated with Tetralogy of Fallot, supporting improved understanding of congenital heart malformations. Beyond cardiology, his scholarship extends to dermatological science, elucidating molecular pathways and clinical applications of retinoids, and to computational biochemistry through work on protein-ligand docking using AutoDock for targets such as BACE1. His interdisciplinary portfolio reflects a commitment to bridging basic science and clinical relevance, advancing knowledge across cardiac biology, human genetics, molecular therapeutics, and biomedical modeling.
Profile: Google Scholar
Featured Publications
Bruneau, B. G., Nemer, G., Schmitt, J. P., Charron, F., Robitaille, L., Caron, S., …
(2001). A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell, 106(6), 709–721.
Grépin, C., Nemer, G., & Nemer, M. (1997). Enhanced cardiogenesis in embryonic stem cells overexpressing the GATA-4 transcription factor. Development, 124(12), 2387–2395.
Charron, F., Paradis, P., Bronchain, O., Nemer, G., & Nemer, M. (1999). Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression. Molecular and Cellular Biology, 19(6), 4355–4365.
Khalil, S., Bardawil, T., Stephan, C., Darwiche, N., Abbas, O., Kibbi, A. G., …
(2017). Retinoids: A journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effects. Journal of Dermatological Treatment, 28(8), 684–696.
Nemer, G., Fadlalah, F., Usta, J., Nemer, M., Dbaibo, G., Obeid, M., & Bitar, F. (2006). A novel mutation in the GATA4 gene in patients with Tetralogy of Fallot. Human Mutation, 27(3), 293–294.
El-Hachem, N., Haibe-Kains, B., Khalil, A., Kobeissy, F. H., & Nemer, G. (Year unavailable). AutoDock and AutoDockTools for protein-ligand docking: Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a case study. Neuroproteomics: Methods and Protocols, 391–403.