Prof.Paula Guedes de Pinho| Oncologia| Excellence in Innovation

PGP graduated in Pharmaceutical Sciences from the Faculty of Pharmacy of the University of Porto (FFUP) and completed a PhD in Medical and Biological Sciences at the University of Bordeaux II, France. Currently, she is a Coordinator Researcher at UCIBIO/FFUP with a permanent contract and an Affiliate Professor (with Habilitation) at the Faculty of Science of the University of Porto. She has published over 200 papers (h-index 48 – Scopus) in international peer-reviewed journals, authored 13 book chapters, and received 15 prizes or awards. PGP established the research line of Metabolomics applied to cancer biomarker discovery at the Laboratory of Toxicology of FFUP, securing funded projects for its development.

Profiles

Scopus

ORCID

Main Education/Training

Habilitation in Toxicology: April 2019, Faculty of Pharmacy, University of Porto. PhD in Biomedical Sciences: Jun. 1991 – Dec. 1994, University of Bordeaux II, France. MS in Pharmaceutical Sciences: Sept. 1989 – Jul. 1990, Faculty of Pharmacy, University of Porto.

Academic and Research Positions

Permanent Contract Researcher at FFUP: Jan. 2023 – Current. Coordinating Researcher at UCIBIO/REQUIMTE (ICETA), Faculty of Pharmacy, University of Porto (Cancer Metabolomics): Jan. 2016 – Current. Affiliate Professor at Faculty of Sciences, University of Porto (teaching Metabolomics at the Master in Bioinformatics and Computational): April 2022 – Current. Assistant Professor, Portuguese Catholic University, School of Biotechnology – Porto (ESB-UCP): Sept. 2001 – May 2005

Major Significant Research Outputs

Editorial Board Member of 5 international journals. Evaluator for scholarship and research projects for various organizations including Agência de Investigação Clínica e Inovação Biomédica (AICIB) and unCAN.eu Delphi. Recipient of 15 prizes or awards

Publications:

Edaravone counteracts redox and metabolic disruptions in an emerging zebrafish model of sporadic ALS

Authors: Oliveira, N.A.S., Pinho, B.R., Pinto, J., Guedes de Pinho, P., Oliveira, J.M.A.
Journal: Free Radical Biology and Medicine, 2024, 217, pp. 126–140

Cisplatin-Resistant Urothelial Bladder Cancer Cells Undergo Metabolic Reprogramming beyond the Warburg Effect

Authors: Afonso, J., Barbosa-Matos, C., Silvestre, R., Longatto-Filho, A., Baltazar, F.
Journal: Cancers, 2024, 16(7), 1418

Identification of key neuronal mechanisms triggered by dimethyl fumarate in SH-SY5Y human neuroblastoma cells through a metabolomic approach

Authors: Araújo, A.M., Marques, S.I., Guedes de Pinho, P., Carvalho, F., Silva, J.P.
Journal: Archives of Toxicology, 2024, 98(4), pp. 1151–1161

Exploiting volatile fingerprints for bladder cancer diagnosis: A scoping review of metabolomics and sensor-based approaches

Authors: Carapito, Â., Roque, A.C.A., Carvalho, F., Pinto, J., Guedes de Pinho, P.
Journal: Talanta, 2024, 268, 125296

Metabolomic Signatures of Treatment Response in Bladder Cancer

Authors: Vieira de Sousa, T., Guedes de Pinho, P., Pinto, J.
Journal: International Journal of Molecular Sciences, 2023, 24(24), 17543

Effect of Rhizobium mechanisms in improving tolerance to saline stress in lettuce plants

Authors: Ayuso-Calles, M., Flores-Félix, J.D., Amaro, F., Escribano-Bailón, M.T., Rivas, R.
Journal: Chemical and Biological Technologies in Agriculture, 2023, 10(1), 89

Metabolic signature biomarkers for predicting the recurrence of urological cancers

Authors: Amaro, F., Carvalho, M., Bastos, M.D.L., Guedes de Pinho, P., Pinto, J.
Journal: Clinica Chimica Acta, 2023, 549, 117553

A Clinically Relevant Dosage of Mitoxantrone Disrupts the Glutathione and Lipid Metabolic Pathways of the CD-1 Mice Brain: A Metabolomics Study

Authors: Dias-Carvalho, A., Margarida-Araújo, A., Reis-Mendes, A., Fernandes, E., Costa, V.M.
Journal: International Journal of Molecular Sciences, 2023, 24(17), 13126

The Redox-Active Manganese(III) Porphyrin, MnTnBuOE-2-PyP5+, Impairs the Migration and Invasion of Non-Small Cell Lung Cancer Cells, Either Alone or Combined with Cisplatin

Authors: Soares, R.B., Manguinhas, R., Costa, J.G., Fernandes, A.S., Oliveira, N.G.
Journal: Cancers, 2023, 15(15), 3814

Paula Guedes de Pinho| Oncologia| Excellence in Innovation