Prof Dr. Esmail El-Fakharany | Biotechnology | Editorial Board Member
research institute | city of scientific research and technological applications | Egypt
Esmail Mohammed El-Fakharany is a researcher at the City of Scientific Research and Technological Applications, known for impactful contributions in virology, protein research, biotechnology, and biochemistry. His work spans antiviral mechanisms, bioactive natural compounds, and biomedical materials. He has extensively studied lactoferrin from multiple species, revealing its potential to inhibit pathogenic viruses, including its ability to reduce hepatitis C virus infectivity in various cell lines. El-Fakharany has also explored antiviral properties of camel milk proteins, casein, and mushroom-derived enzymes, demonstrating their potential roles in preventing viral entry and inducing apoptosis in infected cells. Beyond virology, he contributes to biomaterials research, including developing electrospun nanofibers and polyvinyl alcohol–hyaluronic acid membranes for wound healing. His work further extends to nanotechnology through the synthesis and evaluation of biologically derived platinum nanoparticles with antimicrobial, antioxidant, antidiabetic, and catalytic applications. El-Fakharany’s interdisciplinary research continues to advance understanding of natural antiviral agents, therapeutic biomolecules, and innovative biomedical materials.
Profile: Google Scholar
Featured Publications
El-Gendi, H., Saleh, A. K., Badierah, R., Redwan, E. M., El-Maradny, Y. A., … El-Fakharany, E. M. A comprehensive insight into fungal enzymes: structure, classification, and their role in mankind’s challenges. Journal of Fungi, 8(1), 23.
Hussein, Y., El-Fakharany, E. M., Kamoun, E. A., Loutfy, S. A., Amin, R., Taha, T. H., … El-Magd, M. A. Electrospun PVA/hyaluronic acid/L-arginine nanofibers for wound healing applications: Nanofibers optimization and in vitro bioevaluation. International Journal of Biological Macromolecules, 164, 667–676.
Redwan, E. M., Uversky, V. N., El-Fakharany, E. M., & Al-Mehdar, H. Potential lactoferrin activity against pathogenic viruses. Comptes Rendus Biologies, 337(10), 581–595.
El-Fakharany, E. M., Sánchez, L., Al-Mehdar, H. A., & Redwan, E. M. Effectiveness of human, camel, bovine, and sheep lactoferrin on the hepatitis C virus cellular infectivity: Comparison study. Virology Journal, 10(1), 199.
El-Fakharany, E. M., Haroun, B. M., Ng, T., & Redwan, E. M. Oyster mushroom laccase inhibits hepatitis C virus entry into peripheral blood cells and hepatoma cells. Protein and Peptide Letters, 17(8), 1031–1039.
Fahmy, A., Kamoun, E. A., El-Eisawy, R., El-Fakharany, E. M., Taha, T. H., … Mo, X. Poly(vinyl alcohol)-hyaluronic acid membranes for wound dressing applications: Synthesis and in vitro bio-evaluations. Journal of the Brazilian Chemical Society, 26(7), 1466–1474.
Almahdy, O., El-Fakharany, E. M., Ehab, E. L. D., Ng, T. B., & Redwan, E. M. Examination of the activity of camel milk casein against hepatitis C virus (genotype-4a) and its apoptotic potential in hepatoma and hela cell lines. Hepatitis Monthly, 11(9), 724.