Hangming Dong | Immunology | Best Researcher Award

Dr. Hangming Dong | Immunology | Best Researcher Award

Chief Physician, at Southern medical university, Nanfang hospital, China.

Dr. Hangming Dong is a Chief Physician at Nanfang Hospital, Southern Medical University, China. He holds a Ph.D. in Pulmonary Diseases from Southern Medical University and has over 10 years of experience in respiratory medicine. His expertise includes scientific and clinical research on lung diseases, with a focus on immune checkpoint inhibitors-related interstitial pneumonia for anti-PD1 tumor immunotherapy. Dr. Dong is actively involved in both clinical practice and academic research, contributing to the advancement of pulmonary disease treatment. He is a member of various professional respiratory and lung disease societies and continues to engage in cutting-edge medical research.

Professional Profile

Scopus

ORCID

πŸŽ“ Education

Dr. Hangming Dong earned his Ph.D. in Pulmonary Diseases from Southern Medical University, where he specialized in respiratory medicine and immunotherapy-related lung diseases. His doctoral research focused on preclinical models of immune checkpoint inhibitors-related interstitial pneumonia in the context of anti-PD1 tumor immunotherapy. His education laid the foundation for his multidisciplinary approach to lung diseases, integrating immunology, pulmonology, and clinical research. With a strong academic background, he has participated in various national and international research collaborations and attended advanced training programs in respiratory medicine.

πŸ₯ Experience

With over 10 years of professional experience, Dr. Dong has been serving as a Chief Physician at Nanfang Hospital, Southern Medical University. Throughout his career, he has led multiple research initiatives in pulmonary diseases and played a key role in developing treatment protocols for lung conditions. He has worked extensively on immune-related lung diseases, particularly immunotherapy-induced pneumonia, and has contributed to the diagnosis, management, and treatment of complex respiratory disorders. His clinical expertise, combined with his strong research background, has positioned him as a leading specialist in respiratory medicine.

πŸ”¬ Research Interests

Dr. Dong’s research interests focus on pulmonary diseases, respiratory immunotherapy, and lung inflammation mechanisms. His current work explores preclinical models of immune checkpoint inhibitors-related interstitial pneumonia, aiming to enhance anti-PD1 tumor immunotherapy. He is also engaged in biomarker discovery for lung disease progression, investigating immune responses in pulmonary disorders. His research integrates clinical trials, translational medicine, and molecular pathology to develop innovative diagnostic and treatment strategies. His contributions are pivotal in advancing respiratory medicine and improving lung disease management.

πŸ† Awards

Dr. Dong has been recognized for his contributions to respiratory medicine and pulmonary research. His awards include:

  • Best Researcher Award for his groundbreaking work on immune checkpoint inhibitors-related interstitial pneumonia πŸ…
  • Excellence in Innovation Award for advancements in anti-PD1 tumor immunotherapy πŸ†
  • Distinguished Scientist Award for his outstanding research contributions in pulmonary medicine 🌟
    His achievements highlight his dedication and impact in the field of respiratory health and immunotherapy research.

πŸ“š Top Noted Publications

Dr. Hangming Dong has published several peer-reviewed articles in high-impact journals. Some of his key publications include:

  • Dong, H. (2025). Preclinical models of immune checkpoint inhibitors-related interstitial pneumonia for anti-PD1 tumor immunotherapy. Immunobiology, 230(2), 152884.

    This study focuses on developing preclinical models to investigate interstitial pneumonia associated with immune checkpoint inhibitors, specifically anti-PD-1 therapies. The research employs organoid technology, conditioned co-culture, and humanized mouse models to simulate immune-related adverse events (irAEs). The findings suggest that combining immunotherapy with specific treatments can enhance antitumor activity while mitigating pulmonary toxicity.

  • Dong, H. (2024). Immune response mechanisms in lung diseases: A clinical approach. Respiratory Research.

    This paper explores the mechanisms of immune responses in various lung diseases from a clinical perspective. It delves into the roles of both innate and adaptive immune systems in the pathogenesis of pulmonary conditions. The study highlights how immune system activation leads to the infiltration of T- and B-cells, inducing profibrotic factors and stimulating transforming growth factor-beta (TGF-Ξ²), which plays a crucial role in immune regulation.

  • Dong, H. (2023). Checkpoint inhibitor-related pulmonary toxicity: Diagnosis and management. Journal of Pulmonary Medicine.

    This article addresses the pulmonary toxicities associated with immune checkpoint inhibitors (ICIs), particularly focusing on pneumonitis induced by anti-PD-1/PD-L1 therapies. It reviews the incidence, median time to onset, clinical features, potential mechanisms, management strategies, and predictive biomarkers of checkpoint inhibitor pneumonitis (CIP) in patients with non-small-cell lung cancer (NSCLC). The study emphasizes the need for further characterization of the unique clinical and radiographic features to aid in the diagnosis and management of CIP.

Conclusion

Dr. Hangming Dong is a strong candidate for the Best Researcher Award, given his expertise in pulmonary medicine, impactful research in tumor immunotherapy, and institutional affiliation. However, to strengthen his nomination, he should provide more citation metrics, patents, industry projects, editorial roles, and international collaborations. If these areas are addressed, his chances of winning would significantly increase.

Hai Huang| Prostate cancer| Best Researcher Award

Prof. Hai Huang| Prostate cancer| Best Researcher Award

Professor Hai Huang is a distinguished academic and researcher at Sun Yat-sen Memorial Hospital, specializing in the study of drug resistance mechanisms in prostate cancer. His research primarily focuses on understanding how the tumor microenvironment affects resistance to androgen receptor-targeted therapies and chemotherapy, aiming to develop better treatment strategies and improve patient outcomes. With an impressive portfolio, Professor Huang has completed 30 research projects, published 97 journal articles in SCI and Scopus-indexed journals, authored 9 books, and holds 20 patents.

Profiles

Scopus

Orcid

 

πŸ“šAcademic and Professional Background:

We focus on the research field of drug resistance mechanisms in prostate cancer, aiming to explore the tumor microenvironment’s role in androgen receptor-targeted therapy and chemotherapy resistance. Our work seeks to improve therapeutic strategies and patient outcomes in prostate cancer treatment.

πŸ“ŠΒ Research and Innovations:

Completed/Ongoing Research Projects:Β  30 , Citation Index:Β  (Hai Huang[Author])Β  ANDΒ  (Sun Yat-sen Memorial Hospital [Affiliation]) ,Consultancy/Industry Projects:Β  Prostate Cancer , Books Published (ISBN): Β 9 ,Β Patents Published/Under Process: 20 , Journals Published (SCI, Scopus, etc.):Β  97

🀝 Collaborations:

Qin Jun:Β CAS Key Laboratory of Tissue Microenvironment and Tumor, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Nutrition and Health, Shanghai Jiao Tong University School of Medicine (SJTUSM) & Chinese Academy of Sciences ,Β Β Gao Dong:Β State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences

πŸ†Β Professional Memberships:Β 

American Urological Association, European Association of Urology

πŸ”¬Β Areas of Research:Β 

Prostate cancer treatment resistance

πŸ†Β Contributions :

Focusing on mechanistic research of prostate cancer progression, I have published over 60 SCI papers as the first or corresponding author, with a total impact factor of 507. I have presented at numerous international urological conferences, sharing insights and advancements in prostate cancer treatment.

✍️ Self-Declaration:

I authenticate that to the best of my knowledge, the information given in this form is correct and complete. If at any time I am found to have concealed any material information, my application shall be liable to be summarily terminated without notice. I have read the terms and conditions and other policies of the Awards and agree to them.

πŸ“š Publications :

  • 🧬 Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway
    • Authors: Cheng, B., Li, L., Luo, T., Lai, Y., Huang, H.
    • Journal: Journal of Experimental and Clinical Cancer Research, 2024, 43(1), 67

 

  • πŸ”„ Correction: The key cellular senescence related molecule RRM2 regulates prostate cancer progression and resistance to docetaxel treatment
    • Authors: Cheng, B., Li, L., Wu, Y., Du, T., Huang, H.
    • Journal: Cell and Bioscience, 2024, 14(1), 17

 

  • πŸ”¬ A protein-encoding CCDC7 circular RNA inhibits the progression of prostate cancer by up-regulating FLRT3
    • Authors: Wang, Q., Cheng, B., Singh, S., Li, H., Huang, H.
    • Journal: npj Precision Oncology, 2024, 8(1), 11.

 

  • πŸ’Š Redox responsive polymeric nanoparticles enhance the efficacy of cyclin dependent kinase 7 inhibitor for enhanced treatment of prostate cancer
    • Authors: Tao, Y., Dai, C., Xie, Z., Wu, J., Huang, H.
    • Journal: Chinese Chemical Letters, 2024, 35(8), 109170

 

  • 🧩 Cancer-associated fibroblasts promote enzalutamide resistance and PD-L1 expression in prostate cancer through CCL5-CCR5 paracrine axis
    • Authors: Xiong, Z., Yu, S.-L., Xie, Z.-X., Huang, H., Li, K.-W.
    • Journal: iScience, 2024, 27(5), 109674

 

  • πŸ§ͺ MT1G, an emerging ferroptosis-related gene: A novel prognostic biomarker and indicator of immunotherapy sensitivity in prostate cancer
    • Authors: Cheng, B., Lai, Y., Huang, H., Wang, Q., Huang, H.
    • Journal: Environmental Toxicology, 2024, 39(2), pp. 927–941