Ms. jaishree SANKARANARAYANAN | Microbiology | Best Researcher Award 

Ms. jaishree SANKARANARAYANAN, at chonnam national university, India.

S. Jaishree (DOB: 06/11/1997) 🇮🇳 is an emerging biomedical scientist currently pursuing her Ph.D. in Biomedical Sciences at Chonnam National University, South Korea, with a stellar GPA of 4.17/4.5. Her research journey centers on anti-inflammatory therapies using exosomes derived from mesenchymal stem cells, particularly targeting osteoarthritis. She has hands-on expertise in cutting-edge molecular biology techniques including PCR, ELISA, Western blot, and confocal microscopy. Jaishree has actively presented her work at prestigious international conferences across South Korea and published impactful studies in high-impact journals. Her academic path, marked by perseverance and curiosity, began in India with a B.Sc. and M.Sc. in Microbiology and Medical Microbiology. Fluent in academic collaboration, she aims to revolutionize regenerative medicine. With a strong foundation in experimental and clinical science, her career goal is to become a research scientist and contribute to translational medicine. 🌿

Professional Profile

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🎓 Education

Jaishree’s academic journey reflects her dedication to life sciences and human health. She earned her Ph.D. in Biomedical Sciences (2022–26) from Chonnam National University, Hwasun, South Korea, focusing on clinical oncology, immunology, and biochemistry. Her thesis investigates the anti-inflammatory potential of MSC-derived exosomes in osteoarthritis. 🎓 She completed her M.Sc. in Medical Microbiology (2018–21) at Dr. ALMPGIBMS, University of Madras, with a thesis on the biofilm inhibition properties of natural extracts. During her B.Sc. in Microbiology (2015–18) at Justice Basheer Ahmed Sayeed College for Women, she excelled with distinction, exploring the antibacterial activity of Indian spices. Her educational background also includes Higher Secondary Certification (2015) from Kendriya Vidyalaya, majoring in biology and chemistry. She has consistently demonstrated a passion for biomedical innovation, with solid performance across multidisciplinary domains and an appetite for research that bridges traditional remedies with molecular science. 📘

🧪 Experience

Jaishree has developed robust research capabilities through hands-on roles in molecular biology and regenerative medicine. 🔬 At Chonnam National University, she has been instrumental in isolating and characterizing MSC-derived exosomes, optimizing their extraction using aqueous two-phase systems, and assessing their anti-inflammatory impact. She has mastered core lab techniques like ELISA, RT-PCR, Western blotting, cell culture, and immunofluorescence. In addition, she has contributed to ongoing studies comparing PRP versus PRP-Exosomes for osteoarthritis regression and decellularized ECM for cartilage repair. She also attended a week-long Next-Generation Sequencing workshop at InSTEM, Bengaluru (2021), which enhanced her molecular diagnostic skills. Her engagement in both basic and translational science is evident through numerous conference presentations and poster sessions in Korea. Jaishree’s ability to handle complex bioinformatics, experimental design, and therapeutic modeling positions her as a future leader in biomedical research and innovation. 💡

🔬 Research Interest

Jaishree’s research interests lie at the interface of regenerative medicine, inflammation biology, and exosome-based therapeutics. Her current Ph.D. project explores the therapeutic potential of mesenchymal stem cell-derived exosomes in alleviating inflammation and cartilage degradation in osteoarthritis. She is particularly fascinated by drug delivery systems, MAPK/NF-κB signaling, and molecular mechanisms regulating inflammatory cascades. Additionally, she is involved in comparative efficacy studies of exosomes from different MSC sources and is interested in enhancing the biocompatibility and bioavailability of natural compounds such as cinnamaldehyde. 🌱 Her academic curiosity also extends to biofilm disruption, extracellular matrix engineering, and the clinical translation of anti-inflammatory compounds. Combining molecular techniques and pre-clinical disease models, Jaishree envisions a future where cell-free therapies become mainstream in chronic disease treatment. She is open to collaborative, cross-disciplinary research that spans microbiology, oncology, and immunotherapy. 🧠

🏅 Awards and Conferences

Jaishree has actively presented her research at renowned international conferences. Notable among them are:
📌 Oral Presentation at the Korean Society for Stem Cell and Regenerative Medicine (May 2025) on exosome efficacy from different MSC sources.
📌 Poster Presentations at KMSCB (2022, 2023), showcasing advancements in exosome isolation and anti-inflammatory applications.
📌 OARSI 2025: Poster on suppression of inflammatory mediators via cinnamaldehyde in osteoarthritic models.
📌 21st Fall Conference, Korea (2024): Oral talk on modulation of IL-1β-induced inflammation using bone marrow-derived exosomes.
📌 Workshops & Seminars: Bioinformatics (2017), Genetic Engineering (2017), and NGS training (2021).
These participations highlight her evolving role as a communicator and innovator in biomedical science. 🎤 Her nominations are supported by strong academic references and recognized research excellence. 🏆

📚Top Noted  Publications

Jaishree’s research contributions have been published in high-impact peer-reviewed journals and abstracts.

1. (2025)
   Cinnamaldehyde-Mediated Suppression of Inflammatory Cytokines and Cartilage Degradation in Osteoarthritis Models.
   Osteoarthritis & Cartilage. [Link] — Cited by: 2

2. (2025)
   Synergistic Reduction of Staphylococcus aureus Biofilms Using Cinnamaldehyde and Silver Nanoparticles.
   Preprints. [Link] — Cited by: 0 (Preprint)

3. (2024)
   Cinnamaldehyde-Mediated Suppression of NF-κB and MAPK Pathways in Osteoarthritis Synoviocytes.
   International Journal of Molecular Sciences (IJMS). [Link] — Cited by: 11

4. (2024)
   Cinnamaldehyde-Treated Exosomes via Aqueous Two-Phase System (ATPS) Attenuate Joint Inflammation.
   International Journal of Molecular Sciences (IJMS). [Link] — Cited by: 6

5. (2024)
   HA Viscosupplement Modulates Inflammatory Mediators and Improves Chondrocyte Function in OA Models.
   ACS Omega. [Link] — Cited by: 3

6. (2024)
   Exosomes Reshape the Osteoarthritic Defect Microenvironment and Enhance Cartilage Regeneration.
   International Journal of Stem Cells. [Link] — Cited by: 4

7. (2023)
   Polynucleotides Suppress Inflammation and Promote Extracellular Matrix Remodeling in OA Synoviocytes.
   International Journal of Molecular Sciences (IJMS). [Link] — Cited by: 9

Under Review

• (2025 – Submitted)
  Comparative Efficacy of Exosomes Derived from Different Cell Sources for Osteoarthritic Cartilage Repair.
  Tissue Engineering and Regenerative Medicine (TERM Journal) — (Under Review)

Conclusion

S. Jaishree is a highly suitable candidate for the Best Researcher Award, especially in categories related to early-career excellence in biomedical or translational research. Her consistent research output, international engagement, and applied focus on osteoarthritis therapies using exosomes from mesenchymal stem cells reflect both scientific rigor and innovation. With continued development in leadership roles and expanded collaborative networks, she is poised to become a leading voice in regenerative medicine.