Rouba NASREDDINE | Molecular Diagnostics | Women Researcher Award

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Assoc. Prof. Dr. Rouba NASREDDINE | Molecular Diagnostics | Women Researcher Award 

Doctorate | ICOA | France

Dr. Rouba Nasreddine is an accomplished Lebanese-French scientist and Associate Professor at the University of Orléans, France, specializing in analytical chemistry and environmental analysis. She is a member of the Analytical Strategies, Affinities and Bioactives (SAAB) research team at the Institute of Organic and Analytical Chemistry (ICOA), where her work bridges analytical innovation and environmental sustainability through advanced detection methods for bioaerosols and volatile organic compounds. Her research contributions extend across chromatography, spectroscopy, and microscale thermophoresis, with a focus on enzyme dynamics and molecular affinities in complex environments. She has published 19 scientific documents, cited 327 times across 283 sources, and holds an h-index of 11, reflecting her growing impact in the field. Dr. Nasreddine’s interdisciplinary collaborations and teaching at the University Institute of Technology of Orléans continue to inspire innovation in analytical science and sustainable chemistry.

Profile: Scopus | ORCID

Featured Publications

Nasreddine, R., et al. (2025). Molecules, 30, 4008. [Cited by 12 articles]

Kharrat, O., et al. (2025). PNAS, 122, e2415524122. [Cited by 24 articles]

Kharrat, O., et al. (2025). J. Biol. Chem., 301, 110587. [Cited by 16 articles]

Chartier, S., et al. (2025). Analytica Chimica Acta, 1360, 344145. [Cited by 8 articles]

Quinty, V., et al. (2023). Food Bioscience, 55, 103069. [Cited by 20 articles]

Jan Tesarik | Molecular Diagnostics | Excellence in Research

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Dr. Jan Tesarik | Molecular Diagnostics | Excellence in Research 

Dr. Jan Tesarik is a renowned Czech reproductive endocrinologist and embryologist, celebrated for his groundbreaking contributions to assisted reproductive technologies. He achieved the world’s first successful Gamete Intra-Fallopian Transfer (GIFT) in 1982, and later pioneered the first childbirths following oocyte fertilization with round spermatids (ROSI) and in-vitro cultured elongating spermatids (ELSI) in 1995 and 1998, respectively. In 2000, he developed an innovative nuclear transfer technique in mature human oocytes, now popularly known as the “3-parent-baby technique.” Dr. Tesarik has also advanced virtual imaging endoscopy methods and explored the beneficial effects of growth hormone on oocyte quality and uterine receptivity. Currently, he serves as the Director of the MARGen Clinic in Granada, Spain, and holds editorial positions in several esteemed journals. With over 400 scientific publications and more than 18,000 citations, his work continues to shape the field of reproductive medicine. researchgate.net

Professional Profile

Scopus

🎓 Education 

Dr. Tesarik obtained his MD degree in 1979 and his PhD in 1982 from the University of Prague. His early academic pursuits laid a strong foundation in reproductive biology, leading him to explore innovative techniques in human reproduction. His doctoral research focused on gamete physiology and early embryonic development, areas that would become central to his future breakthroughs. Throughout his academic journey, Dr. Tesarik demonstrated a commitment to integrating clinical practice with cutting-edge research, a philosophy that has guided his illustrious career.

💼 Experience 

Dr. Tesarik’s professional journey spans several decades and continents. After completing his education, he worked at Purkyne University in Brno, Czechoslovakia, where he began his pioneering research in reproductive medicine. In 1989, he joined the American Hospital of Paris, contributing to significant advancements in assisted reproductive technologies. Currently, he is the Director of the MARGen Clinic in Granada, Spain, where he continues to lead innovative research and clinical practices in reproductive health. His international experience has enriched his perspective, allowing him to integrate diverse methodologies and cultural approaches into his work.

🔬 Research Interests 

Dr. Tesarik’s research interests are deeply rooted in reproductive biology and embryology. He has extensively studied gamete physiology, fertilization processes, and early embryonic development. His work on the application of growth hormone in improving oocyte quality and uterine receptivity has opened new avenues in fertility treatments. Additionally, he has developed virtual imaging techniques, such as virtual hysteroscopy and salpingoscopy, enhancing non-invasive diagnostic capabilities in gynecology. In response to the COVID-19 pandemic, Dr. Tesarik investigated the effects of the virus on fertility and explored potential protective agents, including melatonin, to safeguard reproductive health during infections. researchgate.net

🏆 Awards 

Dr. Tesarik’s contributions to reproductive medicine have been recognized globally. Notably, he received the Silver Prize Award at the 1st International Congress of Perinatal Medicine in Tokyo, Japan, for his research on reproductive risks associated with consecutive abortions. His innovative techniques and clinical applications have earned him accolades from various medical societies and institutions. Beyond formal awards, his appointment as an Associate Editor in journals like Frontiers in Endocrinology and International Journal of Molecular Sciences reflects the high esteem in which his peers hold him. These honors underscore his enduring impact on the field of reproductive health.ecronicon.net

📚 Top Noted Publications 

Dr. Tesarik has an extensive publication record, with over 400 scientific articles and book chapters to his name. His works are widely cited, reflecting their significance in the field. Some of his notable publications include:

1. Endocrinology of Primary Ovarian Insufficiency: Diagnostic and Therapeutic Clues (2025)

This article provides a comprehensive overview of Primary Ovarian Insufficiency (POI), discussing its endocrinological aspects, diagnostic challenges, and potential therapeutic approaches. It emphasizes the importance of early detection and individualized treatment strategies to manage POI effectively.

2. Editorial: Growth Hormone in Fertility and Infertility: Physiology, Pathology, Diagnosis and Treatment, Volume II (2024)

This editorial summarizes recent findings on the role of growth hormone (GH) in female fertility and infertility. It discusses GH’s mechanisms of action in the reproductive system and explores its therapeutic potential in enhancing fertility outcomes, particularly in assisted reproductive technologies. frontiersin.org+2frontiersin.org+2researchgate.net+2

3. Mitochondria in Human Fertility and Infertility (2023)

Conclusion

Dr. Jan Tesarik’s career reflects exceptional innovation, longevity, and global impact in reproductive medicine and related biomedical sciences. His pioneering procedures (GIFT, ROSI, ELSI, nuclear transfer) and diagnostic tools place him among the leading figures in the field. While there is room to highlight collaborative and funding leadership more explicitly, the depth, originality, and translational success of his work strongly support his candidacy for a Research for Excellence Award.

Marija Gjorgoska | Molecular Diagnostics | Best Researcher Award

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Ms. Marija Gjorgoska | Molecular Diagnostics | Best Researcher Award 

Asistant, at Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Slovenia.

Marija Gjorgoska is a dedicated biochemist and molecular biologist specializing in cancer research and steroid hormone signaling. Currently a Teaching and Research Assistant at the Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, she contributes to both education and cutting-edge biomedical research. With a strong foundation in LC-MS/MS and bioinformatics, Marija’s work focuses on cancer tissue analysis and hormone-related pathophysiology. Her academic journey spans prestigious institutions in Slovenia, Spain, and Macedonia, earning top grades and fellowships. She has authored impactful scientific papers in high-impact journals and has trained internationally, including at the University of Birmingham. Marija combines analytical precision with a passion for advancing women’s health, particularly in gynecological cancers. Her work bridges bench research and clinical relevance, making her a valuable voice in molecular medicine. Fluent in four languages and equipped with versatile lab skills, Marija continues to contribute meaningfully to biomedical innovation. 🌍🧪📚

Professional Profile

Scopus

🎓 Education

Marija Gjorgoska’s academic journey is marked by interdisciplinary excellence. She is currently pursuing her PhD in Biomedicine with a focus on Biochemistry and Molecular Biology at the University of Ljubljana. Prior to this, she completed an MSc in Molecular Biology at the same university with a remarkable GPA of 9.52/10. Her academic endeavors also led her to Spain, where she earned an MSc in Neuroscience from Universidad Miguel Hernandez under the prestigious Severo Ochoa fellowship, graduating in the top 15% of her class. Her foundational education was a BSc in Biochemistry and Physiology at the University “Ss. Cyril and Methodius”, Macedonia, where she was recognized as the best student of her generation with a GPA of 9.74/10. Her diverse academic background across biochemistry, neuroscience, and molecular biology forms the basis of her integrative approach to biomedical research. 📖🧬🎓

🧪 Experience

Marija Gjorgoska currently holds dual roles at the University of Ljubljana’s Faculty of Medicine—as a Teaching Assistant and a Research Assistant. Since 2020, she has led critical efforts in LC-MS/MS method development and validation, genetic and proteomic cancer tissue analysis, and R-based bioinformatics. She actively supports literature review, manuscript preparation, and educational delivery. Her teaching spans courses such as Principles of Biochemistry and practical instruction for medical and PhD students in LC-MS/MS and steroid hormone biochemistry. Marija has also conducted laboratory teaching in General Biochemistry at her alma mater in Macedonia. Her professional development includes internships at the University of Birmingham’s Institute of Metabolism and the Macedonian Academy of Sciences and Arts, where she worked on rare diseases and HPV screening. Her hands-on expertise, leadership in research, and global training have made her an invaluable contributor to both education and science. 🔬📊👩‍🏫

🔬 Research Interests 

Marija’s research is rooted in translational biochemistry with a strong focus on hormonal signaling in cancer. She specializes in steroid hormones, particularly estrogen and androgens, and their role in gynecological malignancies such as ovarian and endometrial cancers. Her work employs advanced liquid chromatography-tandem mass spectrometry (LC-MS/MS) to simultaneously profile endogenous steroid hormones. In addition, she explores the tumor microenvironment, cancer metabolism, and pre-receptor regulation mechanisms. Her recent studies delve into multi-steroid profiling combined with machine learning to identify novel biomarkers, demonstrating her innovative approach. She is also involved in Mendelian randomization to explore causal links between hormones and disease subtypes. Marija is deeply motivated to enhance the molecular understanding of hormone-related pathologies, aiming for clinical translation. Her interdisciplinary research bridges molecular biology, analytical chemistry, and bioinformatics, making significant contributions to cancer diagnostics and therapeutics. 🧬💉📈

🏆 Awards 

Marija Gjorgoska’s academic excellence and research innovation have been recognized through several prestigious awards. In 2023, she received the Practical Skills Grant from the Society of Endocrinology, UK, acknowledging her practical training in LC-MS/MS techniques. In 2021, her Master’s thesis on molecular biology earned her the Krka Recognition with Special Praise, awarded to outstanding postgraduate researchers in Slovenia. Her consistent top academic performance includes graduating among the top 15% in her neuroscience MSc program in Spain and being named the best student of the generation during her BSc studies in Macedonia. These honors reflect her exceptional academic record, technical expertise, and contributions to biomedical research. Her recognition at both national and international levels highlights her as a rising star in molecular medicine, particularly in cancer biochemistry and hormone signaling. 🏅🎖️📜

📚Top Noted  Publications 

✅ 1. Gjorgoska, M., & Lanišnik-Rižner, T. (2024)

Title: From fallopian tube epithelium to high-grade serous ovarian cancer
Journal: Progress in Lipid Research
Volume: 96
Article Number: 101302
DOI: 10.1016/j.plipres.2024.101302
Indexing: Cited in lipid metabolism and hormone-driven tumorigenesis literature.

✅ 2. Gjorgoska, M., & Lanišnik-Rižner, T. (2022)

Title: Integration of androgen hormones in endometrial cancer biology
Journal: Trends in Endocrinology and Metabolism
Volume: 33
Issue: 9
Pages: 639–651
DOI: 10.1016/j.tem.2022.06.005
Indexing: PubMed, Scopus, Web of Science

✅ 3. Lanišnik-Rižner, T., & Gjorgoska, M. (2024)

Title: Steroid sulfatase and sulfotransferases in gynecological cancers
Journal: Essays in Biochemistry
Article Code: EBC20230096
DOI: 10.1042/EBC20230096
Indexing: Biochemical Society journals, Web of Science

✅ 4. Gjorgoska, M., & Lanišnik-Rižner, T. (2021)

Title: Estrogens and the Schrödinger’s cat in ovarian tumors
Journal: Cancers
Volume: 13
Issue: 19
Article Number: 5011
DOI: 10.3390/cancers13195011
Indexing: PubMed Central, Scopus, DOAJ

✅ 5. Gjorgoska, M., Taylor, A.E., Smrkolj, Š., & Rižner, T.L. (2025)

Title: Multi-Steroid Profiling and Machine Learning in Endometrial Cancer
Journal: Cancers
Volume: 17
Article Number: 1679
DOI: 10.3390/cancers17061679
Indexing: Scopus, Web of Science, PubMed

✅ 6. Gjorgoska, M., & Lanišnik-Rižner, T. (2024)

Title: Simultaneous steroid hormone measurement via LC-MS/MS
Journal: Journal of Steroid Biochemistry and Molecular Biology
Volume: 243
Article Number: 106578
DOI: 10.1016/j.jsbmb.2024.106578
Indexing: PubMed, Scopus, Web of Science

✅ 7. Gjorgoska, M., Šturm, L., & Lanišnik-Rižner, T. (2024)

Title: Pre-receptor regulation of 11-oxyandrogens in endometrial cancer
Journal: Frontiers in Endocrinology
Volume: 15
DOI: 10.3389/fendo.2024.1282059
Indexing: PubMed Central, Web of Science

✅ 8. Marolt, N., Pavlič, R., Kreft, T., Gjorgoska, M., & Lanišnik-Rižner, T. (2024)

Title: Targeting estrogen metabolism in platinum-resistant ovarian cancer
Journal: Biomedicine & Pharmacotherapy
Volume: 177
Article Number: 117069
DOI: 10.1016/j.biopha.2024.117069
Indexing: Scopus, PubMed, Web of Science

✅ 9. Gjorgoska, M., & Lanišnik-Rižner, T. (In Press)

Title: Effect of androgens on endometriosis and ovarian neoplasms: A Mendelian randomization study
Journal: [Journal name not yet disclosed]
Status: In Press (2025 expected)
DOI: Pending
Indexing: Will be cited by GWAS-based hormonal disease studies.

Conclusion

Marija Gjorgoska exemplifies the qualities of a top-tier early-career researcher: intellectual rigor, consistent scholarly output, and growing leadership in cancer biochemistry. Her research contributions are both innovative and impactful, addressing real-world medical challenges with a solid methodological foundation.