Hyo Jin Yoon | Genetics | Best Researcher Award

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Ms. Hyo Jin Yoon | Genetics | Best Researcher Award 

Clinical Laboratory Scientist, Staff member, at National Radiation Emergency Medical Center, Korea Institute of Radiological & Medical Sciences (KIRAMS), South Korea.

Hyo Jin Yoon is an accomplished Clinical Laboratory Scientist with over 15 years of expertise in cytogenetics and biological dosimetry. Based at the National Radiation Emergency Medical Center, Korea Institute of Radiological & Medical Sciences (KIRAMS), she plays a pivotal role in advancing diagnostic and emergency response strategies in radiation exposure cases. Her professional journey includes significant roles at Yonsei University Medical Center and St. Mary’s Hospital. She has been instrumental in developing DiCADE, an AI-driven software for dicentric chromosome analysis, enhancing the accuracy and speed of biodosimetric assessments. A certified ASCPi-IMLT professional, she also serves as a KOLAS Technical Expert for ISO 15189. Through her multidisciplinary approach combining clinical practice, research, and innovation, Hyo Jin continues to elevate global standards in radiation emergency medicine. 🌍🧪💡

Professional Profile

Scopus

🎓 Education 

Hyo Jin began her academic journey in clinical pathology by earning an associate degree from Daejeon Health College, which laid a strong foundation in laboratory sciences. She furthered her education at Eulji University, completing bachelor’s-level coursework with a specialization in medical laboratory technology. Her dedication to professional growth led her to earn the prestigious ASCPi-IMLT certification in 2012, an internationally recognized credential in medical laboratory science. Her continuous pursuit of learning has enabled her to integrate traditional laboratory practices with modern innovations in AI-based diagnostics. 📚👩‍🔬🎓

💼 Experience 

With a distinguished career spanning over 15 years, Hyo Jin Yoon has made significant contributions across clinical, academic, and research domains. She began her professional tenure at Yonsei University Medical Center and later at St. Mary’s Hospital, gaining frontline diagnostic experience in clinical pathology. Since 2015, she has been a core member of the Laboratory of Biodosimetry at KIRAMS-NREME, where she is actively engaged in radiation biodosimetry, diagnostics, and AI-integrated tool development. Her practical insights have been crucial in enhancing laboratory standards and emergency response protocols in radiation medicine. Additionally, as a KOLAS Technical Expert (ISO 15189), she ensures quality and compliance in laboratory operations. 🏥🧬🛡️

🔬 Research Interest

Hyo Jin’s research interests lie at the intersection of cytogenetics, radiation biodosimetry, and medical AI applications. Her core focus is on developing diagnostic tools that improve the biological dose assessment of radiation exposure, particularly during emergencies. Her innovative work on DiCADE—a semi-automated AI-powered dicentric chromosome analysis system—demonstrates her commitment to precision diagnostics. She is deeply involved in international collaboration networks such as RENEB and works with partners like Health Canada and Hirosaki University. Her current research also involves harmonizing scoring standards for cytogenetic assays across biodosimetry networks in South Korea. Her interdisciplinary interests aim to make radiation response faster, more accurate, and globally standardized. 🤖🔎📈

🏆 Awards & Recognitions 

Hyo Jin Yoon’s pioneering work in the field of radiation biodosimetry has earned her respect and recognition across scientific communities. In addition to securing a software copyright for DiCADE (Reg. No. C-2025-019817, dated May 27, 2025), she also has a pending trademark for the tool. As a certified KOLAS Technical Expert, she has contributed to national laboratory quality assurance initiatives. Her participation in international intercomparison exercises with RENEB and Health Canada further reflects her global outreach and credibility. She is a consistent contributor to academic conferences and technical exchange programs, and her work is regarded as a benchmark in South Korea’s preparedness for radiation emergencies. 🥇🔬📜

📚 Top Noted Publications

Hyo Jin Yoon has co-authored six peer-reviewed articles, significantly advancing the field of biological dosimetry:

1. Collaborative Activities in a Biological Dosimetry Network for Radiation Emergencies in South Korea

  • Journal: International Journal of Radiation Biology, 2025

  • Citations: 7

  • Summary:
    This paper presents the establishment and development of a coordinated biological dosimetry network in South Korea. It focuses on preparedness strategies for radiation emergencies, inter-laboratory collaboration, and standardization of methodologies across partner institutions. The paper emphasizes international alignment with IAEA and WHO guidelines and proposes protocols for emergency biodosimetry response.

  • Key Contributions:

    • Strengthens Korea’s radiation emergency response infrastructure.

    • Highlights the importance of capacity building and shared resources.

    • Demonstrates real-case simulations for readiness evaluation.

2. Lessons on Harmonization of Scoring Criteria for Dicentric Chromosome Assay in South Korea

  • Journal: International Journal of Radiation Biology, 2024

  • Citations: 5

  • Summary:
    This study reports on efforts to unify scoring criteria among Korean biodosimetry laboratories for the dicentric chromosome assay (DCA), a key cytogenetic tool in radiation dose assessment. It compares results across labs and discusses discrepancies and consensus-building.

  • Key Contributions:

    • Establishes baseline standards for DCA scoring nationwide.

    • Recommends training protocols and QA practices.

    • Encourages future harmonization with global networks.

3. Application of a Semi-Automated Dicentric Scoring System in Triage and Monitoring Occupational Radiation Exposure

  • Journal: Frontiers in Public Health, 2024

  • Citations: 6

  • Summary:
    This paper evaluates a semi-automated image analysis platform for scoring dicentric chromosomes in metaphase cells. Its application for radiation triage and occupational health surveillance is assessed, showing increased speed and reproducibility.

  • Key Contributions:

    • Reduces manual workload and inter-scorer variability.

    • Supports large-scale triage in radiation emergencies.

    • Offers a model for integrating AI-assisted analysis in routine monitoring.

4. Chromosome Aberration Dynamics in Breast Cancer Patients Treated with Radiotherapy

  • Journal: Mutation Research, 2023

  • Citations: 10

  • Summary:
    This study tracks the temporal profile of chromosome aberrations, including dicentrics and translocations, in breast cancer patients undergoing radiotherapy. It assesses the persistence of aberrations post-treatment as a biomarker of cumulative exposure.

  • Key Contributions:

    • Reveals individual variation in chromosomal response to radiotherapy.

    • Proposes implications for patient-specific radiation sensitivity.

    • Highlights the utility of cytogenetics in post-therapy surveillance.

5. An Intercomparison Exercise to Compare Scoring Criteria and Develop Image Databank for Biodosimetry in South Korea

  • Journal: International Journal of Radiation Biology, 2023

  • Citations: 4

  • Summary:
    This paper documents an inter-laboratory comparison in which multiple Korean institutions scored the same set of metaphase images to assess consistency. It led to the creation of a national image databank to support training and harmonization.

  • Key Contributions:

    • Identifies scoring variability and proposes mitigation strategies.

    • Establishes a digital resource for future reference and QA.

    • Supports IAEA-compliant training infrastructure.

6. Effective Centrifugation Techniques for Improving Metaphase Spreads in Lymphocytopenic Patients

  • Journal: International Journal of Radiation Biology, 2022

  • Citations: 3

  • Summary:
    This methodological paper explores optimized centrifugation protocols to enhance metaphase yield in samples with low lymphocyte counts, such as from immunocompromised or radiotherapy-treated individuals.

  • Key Contributions:

    • Offers practical improvements to sample preparation protocols.

    • Increases metaphase cell quality and scoring accuracy.

    • Beneficial for labs working with difficult patient samples.

Conclusion

Hyo Jin, Yoon demonstrates exceptional dedication to scientific advancement in the field of biological dosimetry, combining clinical excellence with innovative research. Her work in developing AI-driven diagnostic tools and her collaborative efforts in national and international radiation emergency networks make her a highly suitable candidate for the Best Researcher Award. With a few strategic steps to broaden her academic leadership, her impact can be even more significant.

Abdullah Karaer | Molecular Biology | Best Researcher Award

Posted on by Molecular Biologist

Prof. Dr. Abdullah Karaer | Molecular Biology | Best Researcher Award 

Researcher, at Inonu University School of Medicine, Turkey.

Prof. Dr. Abdullah Karaer is a distinguished Turkish physician-scientist specializing in reproductive endocrinology and infertility. Born in 1977, he currently serves as Professor of Obstetrics & Gynecology at Inonu University, where he is also the Head of the IVF Unit and the Department of Obstetrics & Gynaecology. He founded and leads the Reproductive Sciences and Bioinformatics Research and Application Center at the same institution. With over two decades of experience, Dr. Karaer has contributed significantly to women’s health, fertility, and biomedical research. He integrates clinical expertise with advanced bioinformatics and omics technologies to tackle complex reproductive challenges. An active educator and mentor, he continues to shape the next generation of clinicians and scientists. His work has earned over 1000 citations, and his leadership in numerous interdisciplinary projects cements his role as a leading figure in reproductive medicine and academic innovation. 🌐🧪

Professional Profile

Scopus

ORCID

Google Scholar

🎓 Education 

Prof. Dr. Abdullah Karaer’s educational journey is a testament to his commitment to lifelong learning and interdisciplinary excellence. He earned his M.D. from Ankara University in 2001 and completed his specialization in Obstetrics & Gynaecology in 2007, defending a thesis on Y chromosome microdeletions in recurrent pregnancy loss. In 2022, he embarked on a PhD program in Stem Cells and Regenerative Medicine at Ankara University’s Stem Cell Institute, reflecting his interest in cutting-edge medical biotechnology. In 2024, he pursued an Associate’s degree in Computer Programming at Ankara University, signaling his commitment to bioinformatics and digital health. His solid grounding in clinical medicine, coupled with continuous academic development in genomics and informatics, uniquely positions him to lead translational research in reproductive sciences. 🧠📚💻

💼 Experience 

Dr. Karaer’s career spans clinical excellence, academic leadership, and pioneering research. Since 2018, he has served as Professor of Obstetrics & Gynecology at Inonu University, where he also leads the IVF Unit and the Division of Reproductive Endocrinology & Infertility. He founded the Reproductive Sciences and Bioinformatics Research and Application Center in 2019. Previously, he held roles as Associate Professor (2013–2018) and Assistant Professor (2010–2013) at the same university. His early clinical career includes posts at Merzifon Air Military Hospital and Siirt Women’s Health & Children Hospital. A dedicated educator, he mentors students at undergraduate and graduate levels, contributes to national medical education boards, and leads thesis supervision for future medical experts. His integration of patient care with translational research and data-driven solutions has set benchmarks in Turkey’s reproductive medicine landscape. 🏥📈👨‍🏫

🔬 Research Interest 

Prof. Karaer’s research is deeply rooted in reproductive sciences, with a focus on infertility, polycystic ovary syndrome (PCOS), endometriosis, oocyte quality, and assisted reproductive technologies. He harnesses multi-omics techniques—including metabolomics, transcriptomics, and metagenomics—to decode complex biological systems affecting fertility. His work examines the molecular underpinnings of follicular fluid composition, cumulus cell gene expression, and the impact of the vaginal microbiome on IVF outcomes. His interdisciplinary projects incorporate bioinformatics, proteomics, and advanced imaging, making his lab a hub for integrative reproductive biology. As a principal investigator in nationally and internationally funded studies, he collaborates on projects related to PCOS-related endometrial cancer, idiopathic male infertility, and placental pathophysiology in preeclampsia. Dr. Karaer’s innovative approach bridges bench-to-bedside research, aiming to enhance patient outcomes through precision reproductive medicine. 🧫🧬🧠

🏆 Awards 

Prof. Karaer’s career reflects a dedication to scientific excellence and public health impact. While formal award listings are not provided in this record, his leadership roles, continuous academic promotions, and invitations to lead national research projects attest to his recognition as an influential expert in reproductive medicine. He has served on national boards such as the National Medicine Specialty Board in Obstetrics & Gynecology and has been a key member of societies like the European Society of Human Reproduction and Embryology. His ongoing projects funded by TÜBİTAK, TÜSEB, and COST-EU illustrate the high level of trust and investment from both national and international scientific bodies. These honors underscore his capability to lead large-scale, multi-omics, and translational medical research projects addressing fertility and reproductive health. 🏅🌍📖

📚 Top Noted Publications

Dr. Karaer is the author of 65 scientific publications, cited over 1,095 times (Scopus) and 1,922 times (Google Scholar), with an h-index of 19 and 24 respectively. His studies appear in top-tier journals like BJOG, Andrology, Journal of Assisted Reproduction and Genetics, and Fertility and Sterility. His work spans vaginal microbiota, seminal and follicular fluid metabolomics, gene expression in cumulus cells, and endometriosis-related fertility outcomes. Notable publications include:

1. The Vaginal Microbiota Composition of Women Undergoing Assisted Reproduction

  • Journal: BJOG: An International Journal of Obstetrics & Gynaecology

  • Publication Year: 2021

  • Study Type: Prospective cohort study

  • Objective: To investigate the vaginal microbiota composition in women undergoing assisted reproduction and its potential impact on reproductive outcomes.

  • Key Findings: The study identified specific vaginal microbiota profiles associated with reproductive success, suggesting that certain microbial compositions may influence the outcomes of assisted reproductive technologies.

  • Link: PubMed Abstract

2. Metabolomics Analysis of Seminal Plasma in Patients with Idiopathic Oligoasthenoteratozoospermia Using High-Resolution NMR Spectroscopy

  • Journal: Andrology

  • Publication Year: 2020

  • Authors: A. Mumcu, A. Karaer, B. Dogan, G. Tuncay

  • Objective: To determine whether metabolites could serve as potential biomarkers for diagnosing male factor infertility by comparing seminal plasma samples from infertile men with oligoasthenoteratozoospermia (OAT) to those from normozoospermic controls.

  • Key Findings: The study found significant differences in metabolite levels between the two groups, with decreased levels of lactate, citrate, lysine, arginine, valine, glutamine, creatinine, α-ketoglutaric acid, spermine, and putrescine in OAT patients. Tyrosine levels were increased. The PLS-DA model achieved 89.29% sensitivity and 93.55% specificity in distinguishing between the groups.

  • Link: Wiley Online LibraryWiley Online Library

3. The Effect of Seminal Plasma Cadmium and Lead Levels on Semen Parameters in Male Subjects of Infertile Couples: A Prospective Cohort Study

  • Journal: Journal of Obstetrics and Gynaecology

  • Publication Year: 2020

  • Authors: Gorkem Tuncay, Abdullah Karaer, Emrullah Tanrikut, Onur Ozgul

  • Objective: To investigate the relationship between seminal plasma cadmium (Cd) and lead (Pb) levels and semen parameters in male partners of infertile couples.

  • Key Findings: Cadmium levels were significantly higher in men with hypospermia compared to those with normal semen volume (p = .049). No significant differences were observed in lead levels or other semen parameters. The findings suggest that environmental cadmium exposure may contribute to low semen volume.

  • Link: Taylor & Francis OnlineTaylor & Francis Online+1PubMed+1

4. Follicular Fluid Metabolomics in Maternal Aging

  • Journal: Journal of Assisted Reproduction and Genetics (JARG)

  • Publication Year: 2020

  • Objective: To analyze the metabolomic profile of follicular fluid in relation to maternal aging and its impact on oocyte quality and fertility.

  • Key Findings: The study identified age-related changes in the follicular fluid metabolome, suggesting that alterations in specific metabolites may affect oocyte competence and reproductive outcomes in older women.

  • Link: PubMed Abstract

5. Microarray Analysis in Endometriosis

  • Journal: Journal of Endometriosis and Pelvic Pain Disorders (JEPPD)

  • Publication Year: 2020

  • Objective: To utilize microarray analysis to identify gene expression patterns associated with endometriosis.

  • Key Findings: The study revealed specific gene expression profiles in endometrial tissues of patients with endometriosis, providing insights into the molecular mechanisms underlying the disease and potential targets for therapy.

  • Link: PubMed Abstract

Conclusion

Professor Abdullah Karaer is highly suitable for the Best Researcher Award. His multidisciplinary approach, consistent research productivity, leadership in reproductive and bioinformatics research, and proven mentorship make him a standout candidate. With minor enhancements in international engagement and digital presence, his profile would reach even greater global competitiveness.