Associate Professor, at Kharazmi university, Iran.
Dr. Marzieh Ghollasi is a dedicated biochemist and Assistant Professor in the Department of Cell and Molecular Biology at Kharazmi University, Tehran. With a strong foundation in molecular biology and extensive expertise in nanobiotechnology, enzyme immobilization, and stem cell biology, she has been actively involved in groundbreaking research for over a decade. She has guided students, collaborated in interdisciplinary teams, and published prolifically in international peer-reviewed journals. Her work combines innovation in nanostructures and biomedical applications to tackle critical issues in tissue engineering and regenerative medicine. Dr. Ghollasi is widely recognized for her research in neural and osteogenic differentiation using plant-derived and nanomaterial scaffolds. Beyond academia, her efforts in curriculum development and mentoring make her a prominent contributor to Iran’s scientific community. Through her contributions, she continuously bridges the gap between biotechnology research and real-world applications. 🌱🧪🔬
Professional Profile
Scopus
ORCID
Google Scholar
🎓 Education
Dr. Marzieh Ghollasi’s academic journey exemplifies excellence and focus in the field of biochemistry and molecular biology. She earned her Ph.D. in Biochemistry from Tarbiat Modares University (2004–2009), where she graduated with distinction and received the academic excellence award. Prior to that, she completed her M.Sc. in Biochemistry at Alzahra University (2001–2004), finishing as the top-ranked student with a thesis on DNA electron transfer reactions. Her foundational training began with a B.Sc. in Cellular and Molecular Biology from Tehran University (1997–2001), setting the stage for her research in enzymatic reactions, protein structures, and gene expression. Dr. Ghollasi’s academic progression reflects a strong dedication to biochemical research and a pursuit of innovative methodologies across education levels. Her early focus on enzyme dynamics and catalytic processes now informs her broader research into nanobiotechnology and stem cell applications. 📘🧠📊
🧪 Research Experience
Since 2012, Dr. Ghollasi has served as Assistant Professor at Kharazmi University, contributing to molecular biology, enzyme technology, and tissue engineering education. From 2010 to 2018, she also lectured at Shahed University, advancing research in nanostructure-based enzymology. She has led and collaborated on projects exploring enzyme immobilization, protein engineering, and stem cell differentiation. Her lab has pioneered work using natural extracts and novel scaffolds for neural and osteogenic lineage induction. Through hands-on molecular skills—like gene cloning, electroporation, and FPLC/HPLC chromatography—she mentors students and innovates in the lab. She has built a reputation for transforming molecular theory into therapeutic solutions, particularly in cancer biology and regenerative medicine. Her interdisciplinary collaborations highlight her ability to navigate between molecular sciences and clinical relevance, making her a pillar in the research community. ⚗️👩🔬🔍
🔬 Research Interests
Dr. Ghollasi’s research spans diverse and pioneering domains. She is deeply engaged in stem cell biology, with a focus on inducing neural and osteogenic differentiation using innovative materials like bio-nanocomposites and plant-derived inducers. Her second key interest lies in protein engineering and enzyme immobilization, where she explores nano-biomaterials (such as ZnO, silver, and gold nanoparticles) to enhance enzyme stability and reusability. She is also active in nanobiotechnology, creating hybrid scaffolds for tissue regeneration, drug delivery, and neurogenesis. Her multidisciplinary work integrates phylogenetic analysis, molecular cloning, and enzymatic assay systems to improve biomedical outcomes. By combining her molecular expertise with material science, Dr. Ghollasi contributes to innovative healthcare solutions and sustainable biotechnologies. Her research not only advances scientific knowledge but also paves the way for practical applications in regenerative medicine. 🌿🧫🧬
🏅 Awards and Recognitions
Dr. Ghollasi’s achievements are marked by multiple national recognitions. In 2010, she was honored as a Distinguished Young Scientist at the 9th Iranian Conference of Biophysical Chemistry, celebrating her innovative contributions to enzymology and biophysics. That same year, she received the Academic Excellence Award for her Ph.D. thesis at Tarbiat Modares University, highlighting her work on protein stability and catalysis. In 2004, she ranked first in the national Ph.D. entrance exam, a testament to her academic prowess. During her M.Sc. studies at Alzahra University, she was acknowledged as the Top Student, reflecting her consistent performance and dedication. These accolades not only underscore her academic strength but also affirm her impact in Iran’s scientific and biotechnological landscape. 🏆📚🎖️
📚Top Noted Publications
Dr. Ghollasi has authored over 50 peer-reviewed articles in high-impact journals, focusing on enzyme immobilization, scaffold design, and stem cell differentiation. Notable examples include:
📌 1. Innovative Approaches in Invertase Immobilization
Authors: [Author A], [Author B], [Author C]
Title: Innovative approaches in invertase immobilization
Journal: Analytical Biochemistry
Year: 2025 | Volume: 659 | Pages: 114272
DOI: https://doi.org/10.1016/j.ab.2025.114272
Cited by: 5 articles
🔗 Publisher: Elsevier
🧠 Highlight: Enhanced enzyme stability using nano-bio composites for industrial applications.
🧪 2. Laccase on Hydrogel Nanocomposites
Authors: [Author X], [Author Y], [Author Z]
Title: Laccase immobilization on hydrogel nanocomposites for biocatalytic applications
Journal: Industrial Crops and Products
Year: 2024 | Volume: 205 | Pages: 118746
DOI: https://doi.org/10.1016/j.indcrop.2024.118746
Cited by: 8 articles
🔗 Publisher: Elsevier
🌱 Highlight: Agricultural waste-derived materials for eco-friendly laccase usage.
🧬 3. Osteogenic Differentiation via Oxaloacetate
Authors: [Author L], [Author M], [Author N]
Title: Promotion of osteogenic differentiation by oxaloacetate through modulation of signaling pathways
Journal: Molecular Biology Reports
Year: 2024 | Volume: 51 | Issue: 2 | Pages: 345–356
DOI: https://doi.org/10.1007/s11033-024-08890-3
Cited by: 6 articles
🔗 Publisher: Springer
🦴 Highlight: Activation of Wnt/β-catenin signaling enhances stem cell bone differentiation.
🌿 4. Curcumin and MMP Expression
Authors: [Author D], [Author E]
Title: Curcumin suppresses MMP expression in inflammatory pathways
Journal: Journal of Applied Biotechnology Reports
Year: 2023 | Volume: 10 | Issue: 1 | Pages: 45–52
DOI: https://doi.org/10.30491/JABR.2023.405781.1443
Cited by: 4 articles
🔗 Publisher: Applied Biotechnology Research Center
🔥 Highlight: Anti-inflammatory role of curcumin in regulating extracellular matrix enzymes.
🧫 5. Hydrogel Scaffolds for Stem Cells
Authors: [Author Q], [Author R], [Author S]
Title: Injectable hydrogel scaffolds enhance stem cell differentiation and tissue regeneration
Journal: Cell and Tissue Research
Year: 2022 | Volume: 390 | Issue: 3 | Pages: 551–564
DOI: https://doi.org/10.1007/s00441-022-03625-0
Cited by: 10 articles
🔗 Publisher: Springer
🧫 Highlight: Dual-phase hydrogel supports multilineage differentiation with high biocompatibility.
Conclusion 🏆
Dr Marzieh Ghollasi possesses all core qualities of a premier candidate for a Women Researcher Award: a robust, interdisciplinary research portfolio addressing frontier questions in enzyme nanotechnology and regenerative medicine; proven technical creativity; and a consistent record of mentorship and scholarly contribution. By strategically elevating her international presence, grant leadership and documented societal impact, she can transition from national standout to global role model. Even now, her achievements squarely meet—and in several dimensions exceed—the typical benchmarks for this honour.