José A Sánchez Alcázar | Neurodegeneration | Best Researcher Award

Dr. José A Sánchez Alcázar | Neurodegeneration | Best Researcher Award 

Professor, at Pablo de oLavide University, Spain.

🌟 José Antonio Sánchez Alcázar is a distinguished Spanish researcher specializing in cellular biology and rare diseases. Currently a Professor at Universidad Pablo de Olavide, he has made significant contributions to mitochondrial research and neurodegenerative disorders. With over 23 years of teaching experience, he has guided numerous Ph.D. students and led multiple research projects. His work has been widely cited, demonstrating his influence in the field. He has received prestigious awards, including the SERONO Research Award and the MERCK Research Award, highlighting his outstanding contributions to biomedical sciences.

Professional Profile

ORCID

Education 🎓

Dr. Sánchez Alcázar obtained his Doctorate in Biochemistry, Molecular Biology, and Biomedicine from Universidad Complutense, Madrid (1995). His academic foundation includes a Clinical Biochemistry degree from Hospital 12 de Octubre de Madrid (1990), a Medicine degree from Universidad de Sevilla (1986), and a Biology degree from Universidad de Sevilla (1980). His extensive educational background has enabled him to excel in cellular biology and rare disease research.

Experience 💼

With an illustrious career spanning decades, Dr. Sánchez Alcázar has held various positions in prestigious institutions. He conducted predoctoral research in Spain (1993-1996), followed by postdoctoral studies in the USA (1997-2000) and the UK (2000-2001) focusing on apoptosis. Since 2001, he has been affiliated with Universidad Pablo de Olavide, serving as a postdoctoral researcher, Associate Professor (2008-2018), and Full Professor (2018-present). His leadership in numerous national and international research projects has solidified his reputation as a leading scientist.

Research Interests 🔬

Dr. Sánchez Alcázar’s research focuses on cellular biology, mitochondrial dysfunction, and rare diseases. His work explores the molecular mechanisms of neurodegeneration, lipid peroxidation, and oxidative stress. He has contributed to understanding mitochondrial unfolded protein response (mtUPR) and its therapeutic potential for mitochondrial diseases. His research integrates patient-derived cellular models to develop precision medicine approaches for neurodegenerative disorders.

Awards 🏆

Recognized for his groundbreaking research, Dr. Sánchez Alcázar has received prestigious awards, including the SERONO Research Award (1992) and the MERCK Research Award (2019). His contributions to rare disease studies and mitochondrial research have garnered international acclaim. Additionally, eight of the Ph.D. theses he has supervised have received Extraordinary Doctorate Awards, further underscoring his impact on academia and scientific advancement.

Top Noted Publications 📖

Dr. Sánchez Alcázar has published 127 research papers with over 13,355 citations and an h-index of 42. His recent publications include:

  • Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration (2023) – Neural Regen Res
  • mtUPR Modulation as a Therapeutic Target for Mitochondrial Diseases (2023) – Int J Mol Sci
  • Neurodegeneration, Mitochondria, and Antibiotics (2023) – Metabolites
  • Alpha-lipoic acid supplementation in PKAN cellular models (2023) – Orphanet J Rare Dis
  • Antioxidants and mitochondrial bioenergetics in BPAN models (2023) – Int J Mol Sci
  • Polytarget Precision Medicine in PKAN (2023) – Pharmaceuticals
  • Actin Polymerization Defects in Nemaline Myopathies (2023) – Antioxidants
  • Mitochondrial UPR in Aging and Neurodegenerative Diseases (2023) – Antioxidants

Conclusion

José Antonio Sánchez Alcázar is a highly qualified candidate for the Best Researcher Award, with a strong publication record, impactful research in rare diseases, and substantial contributions to academia and mentoring. His leadership in cellular biology and mitochondrial dysfunction, combined with scientific recognition and project management expertise, makes him an excellent nominee. Strengthening global collaborations and industry applications could further enhance his profile for this and future awards.

 

Ahmed Khedr | Genetics | Excellence in Research

Assist. Prof. Dr. Ahmed Khedr | Genetics | Excellence in Research 

Assistant Professor Doctorate, at Faculty of Medicine, Helwan University, Egypt.

Ahmed MB Khedr is an accomplished medical biochemist and molecular biologist, currently serving as a Lecturer (Assistant Professor) at the Faculty of Medicine, Helwan University. His research focuses on the role of microRNAs and long non-coding RNAs in systemic and autoimmune diseases, particularly multiple sclerosis and systemic sclerosis. With a strong academic foundation and extensive teaching experience, he has contributed significantly to the fields of molecular biology and clinical biochemistry. Dr. Khedr has also been an active reviewer for renowned journals and has several peer-reviewed publications to his credit. His dedication to medical research and education has earned him recognition in academia and beyond.

Professional Profile

Scopus

Education 🎓

Dr. Ahmed MB Khedr holds a Ph.D. in Medical Biochemistry and Molecular Biology from Cairo University (2023), where he investigated MiRNA-133 and lncRNA-H19 expressions in systemic sclerosis patients. He earned his MSc from Cairo University (2020), focusing on the relationship between MiRNA-22, vitamin D, and its receptor in multiple sclerosis patients. His academic journey began with a Bachelor of Medicine and Surgery (MBBCH) from Benha University in 2014. His education has provided him with a robust background in medical biochemistry, equipping him with the expertise to advance research in molecular diagnostics and disease pathogenesis.

Experience 🌟

Dr. Khedr has over eight years of academic and clinical experience. He has been a Lecturer at Batterjee Medical College since 2023 and previously served as an Assistant Lecturer at Helwan University from 2020 to 2023. He also worked as a Demonstrator at Helwan University (2017-2020), a General Practitioner at the Ministry of Health in Egypt (2016-2017), and a House Officer at Benha University Hospitals (2015-2016). Throughout his career, he has taught medical biochemistry to students across various faculties, including medicine, physical therapy, nursing, and allied health sciences, while also coordinating laboratory courses and exams.

Research Interests 📝

Dr. Khedr’s research is centered on molecular mechanisms underlying systemic diseases. His primary focus is on microRNAs and long non-coding RNAs in autoimmune and neurological disorders such as systemic sclerosis and multiple sclerosis. His work explores the diagnostic and prognostic potential of these biomarkers in disease progression. Additionally, he investigates biochemical pathways linked to vitamin D metabolism, oxidative stress, and inflammatory signaling. His contributions aim to enhance molecular diagnostics and therapeutic strategies for complex diseases.

Awards & Recognition 🏆

Dr. Khedr has received multiple awards and recognitions for his academic contributions. In February 2019, he was awarded an Appreciation Certificate for his participation in the Quality Assurance and Accreditation Unit and community services at Helwan University. In January 2019, he was recognized as a qualified member of the First Aid Workshop at the Faculty of Medicine, Helwan University. His dedication to academic excellence and community service has positioned him as a key figure in medical education and research.

Top Notes Publications 📚

  • Khedr et al. (2024)
    • Title: MiRNA-133 and lncRNA-H19 expressions and their relation to serum levels of PKM2 and TGF-β in patients with systemic sclerosis.
    • Journal: Non-Coding RNA Research
    • Key Findings:
      • Investigates the expression levels of MiRNA-133 and lncRNA-H19 in systemic sclerosis patients.
      • Analyzes their correlation with serum PKM2 (pyruvate kinase M2) and TGF-β (Transforming Growth Factor-beta).
      • Findings suggest potential biomarkers for systemic sclerosis.
    • DOI: 10.1016/j.ncrna.2023.12.003
  • Mohamad et al. (2023)
    • Title: Expression of Long Noncoding RNA, HOTAIR, and MicroRNA-205 and Their Relation to Transforming Growth Factor β1 in Patients with Alopecia Areata.
    • Journal: Skin Appendage Disorders
    • Key Findings:
      • Examines the role of HOTAIR (lncRNA) and miRNA-205 in alopecia areata.
      • Explores their relationship with TGF-β1, which plays a role in immune response and hair follicle cycling.
      • Suggests that these ncRNAs may be involved in the pathogenesis of alopecia areata.
    • DOI: 10.1159/000527851
  • Khedr et al. (2022)
    • Title: MicroRNA-22 Level in Patients with Multiple Sclerosis and Its Relationship with Vitamin D and Vitamin D Receptor Levels.
    • Journal: Neuroimmunomodulation
    • Key Findings:
      • Investigates miRNA-22 levels in multiple sclerosis (MS) patients.
      • Studies its correlation with Vitamin D and Vitamin D receptor (VDR) levels.
      • Findings indicate a potential regulatory role of miRNA-22 in MS progression and Vitamin D metabolism.
    • DOI: 10.1159/000519012

Conclusion

Dr. Ahmed MB Khedr is a strong candidate for Research for Excellence in Research due to his solid academic background, research expertise, peer-review contributions, and teaching experience. To further enhance his competitiveness, he should focus on increasing high-impact publications, securing grants, expanding collaborations, and gaining more international recognition. With continued research advancements, he has significant potential to achieve excellence in his field.