jinghui xie | Molecular Biology | Best Researcher Award

Published on by Molecular Biologist

Mr. jinghui xie | Molecular Biology | Best Researcher Award 

Associate professor, at xinjiang medical university, China.

Dr. Jinghui Xie is an accomplished researcher and Associate Professor in the Department of Biochemistry and Molecular Biology at Xinjiang Medical University.  He holds a Doctor of Science (Ph.D.) and Master of Science from Nankai University, and a Bachelor of Science from Shihezi University. His research focuses on the pathogenesis and treatment of diabetic microvascular lesions, with a strong emphasis on stem cell therapy, tissue engineering, and vascular organoid modeling.  Dr. Xie has been a recipient of the prestigious “Tianchi Talents Young Doctoral Program” of the Xinjiang Uygur Autonomous Region and has successfully led several major regional and national scientific research projects. 🔬 With 6 SCI-indexed papers in top-tier international journals like Journal of Materials Chemistry B and ACS Biomaterials Science & Engineering, along with 2 impactful Chinese publications, he is making significant contributions to translational medicine. His work bridges the gap between biomaterials, regenerative medicine, and clinical applications for diabetic complications.

Professional Profile

Google Scholar

🎓 Education

Dr. Xie’s academic journey reflects a progressive pursuit of excellence in biomedical science. 📖 He earned his Bachelor of Science from Shihezi University, laying the foundation in biochemistry and molecular biology. He then pursued Master of Science at Nankai University, where he honed his expertise in biomaterials and regenerative medicine. 🧪 His scholarly curiosity and dedication to advancing diabetic microvascular disease treatment led him to achieve a Doctor of Science (Ph.D.) in Biochemistry and Molecular Biology at Nankai University. During his Ph.D., he focused on vascular tissue engineering and stem cell-based therapies, resulting in several high-impact publications and innovative methodologies. 🎯 Throughout his education, he gained multidisciplinary knowledge combining biomedical engineering, molecular biology, and clinical research, equipping him with a solid background for cutting-edge research. 🎓💡

💼 Experience

Dr. Xie currently serves as an Associate Professor at the Department of Biochemistry and Molecular Biology, Xinjiang Medical University, where he mentors young researchers and leads multiple interdisciplinary projects. 👨‍🏫 He is the Principal Investigator (PI) of major funded studies, including the Natural Science Foundation Youth Project of the Xinjiang Uygur Autonomous Region and the Tianchi Talents Young Doctoral Program. 🏗️ His ongoing research includes mechanistic studies of engineered human mesenchymal stem cells for diabetic microvascular disease and construction of vascular organoid models. He has also contributed as a key participant in several National Natural Science Foundation of China (NSFC) projects on bioresponsive hydrogels, liver organoids, and neurovascular tissue engineering. 🔬 Beyond research, Dr. Xie actively contributes to academic development through teaching, curriculum improvement, and editorial roles in medical education journals. 🏅

🔬 Research Interests

Dr. Xie’s research is deeply rooted in regenerative medicine, biomaterials, and vascular biology. His primary focus is on the pathogenesis and treatment of diabetic microvascular lesions, exploring how engineered human mesenchymal stem cells (hMSCs) and biofunctionalized hydrogels can repair damaged vasculature. 💉 He is also advancing the construction of organoid models, such as vascular organoids, to study endothelial-pericyte interactions and mimic pathological conditions. 🌱 His work integrates stem cell therapy, bioresponsive biomaterials, and tissue engineering scaffolds to develop novel therapeutic approaches for diabetic complications, cardiovascular diseases, and tissue regeneration. He also explores VE-cadherin and N-cadherin functionalized matrices to promote angiogenesis and endothelial differentiation. 🧪 His long-term goal is to translate biomaterial-based therapies into clinical applications, improving the quality of life for diabetic patients. 🌟

🏆 Awards & Honors

Dr. Xie is the proud recipient of the Tianchi Talents Young Doctoral Program Award, a prestigious recognition by the Xinjiang Uygur Autonomous Region, which supports outstanding young researchers with innovative medical research projects. 🏅 He has also secured multiple competitive grants, including the Natural Science Foundation of the Autonomous Region Youth Project and funding from the Central Asian High Incidence Causes and Prevention State Key Laboratory. 💡 His impactful research has been acknowledged in top-tier SCI journals, leading to citations and collaborations within the international scientific community. 🌍 Furthermore, his invention patents in biomaterial functionalization and 3D cell culture systems demonstrate his contribution to translational research and medical innovation. 🚀

📚 Top Noted Publications 

Dr. Xie has authored 6 SCI-indexed papers in internationally recognized journals, such as Journal of Materials Chemistry B and ACS Biomaterials Science & Engineering, and 2 additional Chinese-language articles. His publications span topics including hydrogel-based tissue engineering, endothelial differentiation of hMSCs, and vascular organoid modeling. 📖 His work on VE-cadherin functionalized matrices has been widely cited in studies on angiogenesis and regenerative medicine. ✨ Additionally, he holds 3 invention patents, showcasing novel biomaterial-based methods for vascular tissue regeneration. His research contributions have been cited in applied biomaterials, cardiovascular therapy, and diabetes-related tissue engineering studies, reinforcing his influence in the field. 🌐

🔗 Representative Publications with Citation Prompt

📄 1️⃣ Lv C, Li S, Sang M, Cui T, Xie J.
Title: Construction of Microsphere Culture System for Human Mesenchymal Stem Cell Aggregates
Journal: International Journal of Molecular Sciences
Year: 2025, Volume 26, Article 6435
Link: 🔗 Read Here
Citation Context: Frequently cited in organoid culture system research for its innovative approach to MSC aggregate formation.

📄 2️⃣ Jinghui Xie, Xiaoning Li, Yan Zhang, et al.
Title: VE-Cadherin based matrix promoting self-reconstruction of proangiogenic microenvironment
Journal: Journal of Materials Chemistry B
Year: 2021, 9(1), pp. 3357–3370
Link: 🔗 Read Here
Citation Context: Referenced in endothelial differentiation studies exploring angiogenic microenvironments.

📄 3️⃣ Yuanning Lyu, Jinghui Xie, Yang Liu, et al.
Title: Injectable Hyaluronic Acid Hydrogel for Myocardial Repair
Journal: ACS Biomaterials Science & Engineering
Year: 2020, 6(12), pp. 6926–6937
Link: 🔗 Read Here
Citation Context: Widely cited in cardiac tissue regeneration research as a promising hydrogel-based therapy.

📄 4️⃣ Yang Jun, Xie Jinghui, Gao Chao, et al.
Title: VE-cad-Fc Functionalized Hyaluronic Acid Hydrogel
Journal: Journal of Tianjin University
Year: 2019, 52(1), pp. 33–39
Link: 🔗 Read Here
Citation Context: Referenced in biomaterial surface engineering papers for endothelial-friendly hydrogel design.

📄 5️⃣ Chao Gao, Yan Zhang, Jinghui Xie, et al.
Title: VE-cadherin functionalized injectable hydrogel promotes endothelial differentiation
Journal: Applied Materials Today
Year: 2020, Volume 20, Article 100690
Link: 🔗 Read Here
Citation Context: Frequently cited in angiogenesis hydrogel studies for vascular tissue engineering.

📄 6️⃣ Ke Xu, Chuanshun Zhu, Jinghui Xie, et al.
Title: Enhanced Vascularization of PCL Scaffolds through VEGF-Fc
Journal: Journal of Materials Chemistry B
Year: 2018, 6(6), p. 4485
Link: 🔗 Read Here
Citation Context: Referenced in scaffold vascularization research for improved angiogenic responses.

🏆 Conclusion

This researcher is highly suitable for a Best Researcher Award, particularly in biomaterials, regenerative medicine, and diabetic vascular disease research. Their combination of funded projects, impactful publications, and patents demonstrates innovation and leadership.

Hyo Jin Yoon | Genetics | Best Researcher Award

Published on by Molecular Biologist

Ms. Hyo Jin Yoon | Genetics | Best Researcher Award 

Clinical Laboratory Scientist, Staff member, at National Radiation Emergency Medical Center, Korea Institute of Radiological & Medical Sciences (KIRAMS), South Korea.

Hyo Jin Yoon is an accomplished Clinical Laboratory Scientist with over 15 years of expertise in cytogenetics and biological dosimetry. Based at the National Radiation Emergency Medical Center, Korea Institute of Radiological & Medical Sciences (KIRAMS), she plays a pivotal role in advancing diagnostic and emergency response strategies in radiation exposure cases. Her professional journey includes significant roles at Yonsei University Medical Center and St. Mary’s Hospital. She has been instrumental in developing DiCADE, an AI-driven software for dicentric chromosome analysis, enhancing the accuracy and speed of biodosimetric assessments. A certified ASCPi-IMLT professional, she also serves as a KOLAS Technical Expert for ISO 15189. Through her multidisciplinary approach combining clinical practice, research, and innovation, Hyo Jin continues to elevate global standards in radiation emergency medicine. 🌍🧪💡

Professional Profile

Scopus

🎓 Education 

Hyo Jin began her academic journey in clinical pathology by earning an associate degree from Daejeon Health College, which laid a strong foundation in laboratory sciences. She furthered her education at Eulji University, completing bachelor’s-level coursework with a specialization in medical laboratory technology. Her dedication to professional growth led her to earn the prestigious ASCPi-IMLT certification in 2012, an internationally recognized credential in medical laboratory science. Her continuous pursuit of learning has enabled her to integrate traditional laboratory practices with modern innovations in AI-based diagnostics. 📚👩‍🔬🎓

💼 Experience 

With a distinguished career spanning over 15 years, Hyo Jin Yoon has made significant contributions across clinical, academic, and research domains. She began her professional tenure at Yonsei University Medical Center and later at St. Mary’s Hospital, gaining frontline diagnostic experience in clinical pathology. Since 2015, she has been a core member of the Laboratory of Biodosimetry at KIRAMS-NREME, where she is actively engaged in radiation biodosimetry, diagnostics, and AI-integrated tool development. Her practical insights have been crucial in enhancing laboratory standards and emergency response protocols in radiation medicine. Additionally, as a KOLAS Technical Expert (ISO 15189), she ensures quality and compliance in laboratory operations. 🏥🧬🛡️

🔬 Research Interest

Hyo Jin’s research interests lie at the intersection of cytogenetics, radiation biodosimetry, and medical AI applications. Her core focus is on developing diagnostic tools that improve the biological dose assessment of radiation exposure, particularly during emergencies. Her innovative work on DiCADE—a semi-automated AI-powered dicentric chromosome analysis system—demonstrates her commitment to precision diagnostics. She is deeply involved in international collaboration networks such as RENEB and works with partners like Health Canada and Hirosaki University. Her current research also involves harmonizing scoring standards for cytogenetic assays across biodosimetry networks in South Korea. Her interdisciplinary interests aim to make radiation response faster, more accurate, and globally standardized. 🤖🔎📈

🏆 Awards & Recognitions 

Hyo Jin Yoon’s pioneering work in the field of radiation biodosimetry has earned her respect and recognition across scientific communities. In addition to securing a software copyright for DiCADE (Reg. No. C-2025-019817, dated May 27, 2025), she also has a pending trademark for the tool. As a certified KOLAS Technical Expert, she has contributed to national laboratory quality assurance initiatives. Her participation in international intercomparison exercises with RENEB and Health Canada further reflects her global outreach and credibility. She is a consistent contributor to academic conferences and technical exchange programs, and her work is regarded as a benchmark in South Korea’s preparedness for radiation emergencies. 🥇🔬📜

📚 Top Noted Publications

Hyo Jin Yoon has co-authored six peer-reviewed articles, significantly advancing the field of biological dosimetry:

1. Collaborative Activities in a Biological Dosimetry Network for Radiation Emergencies in South Korea

  • Journal: International Journal of Radiation Biology, 2025

  • Citations: 7

  • Summary:
    This paper presents the establishment and development of a coordinated biological dosimetry network in South Korea. It focuses on preparedness strategies for radiation emergencies, inter-laboratory collaboration, and standardization of methodologies across partner institutions. The paper emphasizes international alignment with IAEA and WHO guidelines and proposes protocols for emergency biodosimetry response.

  • Key Contributions:

    • Strengthens Korea’s radiation emergency response infrastructure.

    • Highlights the importance of capacity building and shared resources.

    • Demonstrates real-case simulations for readiness evaluation.

2. Lessons on Harmonization of Scoring Criteria for Dicentric Chromosome Assay in South Korea

  • Journal: International Journal of Radiation Biology, 2024

  • Citations: 5

  • Summary:
    This study reports on efforts to unify scoring criteria among Korean biodosimetry laboratories for the dicentric chromosome assay (DCA), a key cytogenetic tool in radiation dose assessment. It compares results across labs and discusses discrepancies and consensus-building.

  • Key Contributions:

    • Establishes baseline standards for DCA scoring nationwide.

    • Recommends training protocols and QA practices.

    • Encourages future harmonization with global networks.

3. Application of a Semi-Automated Dicentric Scoring System in Triage and Monitoring Occupational Radiation Exposure

  • Journal: Frontiers in Public Health, 2024

  • Citations: 6

  • Summary:
    This paper evaluates a semi-automated image analysis platform for scoring dicentric chromosomes in metaphase cells. Its application for radiation triage and occupational health surveillance is assessed, showing increased speed and reproducibility.

  • Key Contributions:

    • Reduces manual workload and inter-scorer variability.

    • Supports large-scale triage in radiation emergencies.

    • Offers a model for integrating AI-assisted analysis in routine monitoring.

4. Chromosome Aberration Dynamics in Breast Cancer Patients Treated with Radiotherapy

  • Journal: Mutation Research, 2023

  • Citations: 10

  • Summary:
    This study tracks the temporal profile of chromosome aberrations, including dicentrics and translocations, in breast cancer patients undergoing radiotherapy. It assesses the persistence of aberrations post-treatment as a biomarker of cumulative exposure.

  • Key Contributions:

    • Reveals individual variation in chromosomal response to radiotherapy.

    • Proposes implications for patient-specific radiation sensitivity.

    • Highlights the utility of cytogenetics in post-therapy surveillance.

5. An Intercomparison Exercise to Compare Scoring Criteria and Develop Image Databank for Biodosimetry in South Korea

  • Journal: International Journal of Radiation Biology, 2023

  • Citations: 4

  • Summary:
    This paper documents an inter-laboratory comparison in which multiple Korean institutions scored the same set of metaphase images to assess consistency. It led to the creation of a national image databank to support training and harmonization.

  • Key Contributions:

    • Identifies scoring variability and proposes mitigation strategies.

    • Establishes a digital resource for future reference and QA.

    • Supports IAEA-compliant training infrastructure.

6. Effective Centrifugation Techniques for Improving Metaphase Spreads in Lymphocytopenic Patients

  • Journal: International Journal of Radiation Biology, 2022

  • Citations: 3

  • Summary:
    This methodological paper explores optimized centrifugation protocols to enhance metaphase yield in samples with low lymphocyte counts, such as from immunocompromised or radiotherapy-treated individuals.

  • Key Contributions:

    • Offers practical improvements to sample preparation protocols.

    • Increases metaphase cell quality and scoring accuracy.

    • Beneficial for labs working with difficult patient samples.

Conclusion

Hyo Jin, Yoon demonstrates exceptional dedication to scientific advancement in the field of biological dosimetry, combining clinical excellence with innovative research. Her work in developing AI-driven diagnostic tools and her collaborative efforts in national and international radiation emergency networks make her a highly suitable candidate for the Best Researcher Award. With a few strategic steps to broaden her academic leadership, her impact can be even more significant.