Kaixia Mi | Microbiology | Best Researcher Award

Published on by Molecular Biologist

Prof. Kaixia Mi | Microbiology | Best Researcher Award 

Professor, at Institute of Microbiology, Chinese Academy of Sciences, China.

Dr. Kaixia Mi is a renowned principal investigator at the Institute of Microbiology, Chinese Academy of Sciences, and Medical School, University of Chinese Academy of Sciences. 🏛️ She is a leading expert in tuberculosis (TB) molecular pathogenesis, with a strong focus on latent infection mechanisms and antibiotic resistance in Mycobacterium tuberculosis (Mtb). 🧪 Dr. Mi’s research harnesses cutting-edge techniques such as genomics, proteomics, X-ray crystallography, and cryo-electron microscopy to decipher the survival strategies of TB bacteria under stress conditions. Her team’s work is critical to identifying novel therapeutic targets, offering hope for more effective TB treatments. 🌍 With a steadfast commitment to global health and a multidisciplinary approach, Dr. Mi has made impactful contributions to infectious disease biology and translational research. Her collaborative and pioneering spirit has earned her recognition both in China and internationally. 🥼

Professional Profile

Scopus

🎓 Education

Dr. Kaixia Mi completed her Ph.D. in Microbiology at a prestigious Chinese institution, where she developed a strong foundation in bacterial pathogenesis and host-microbe interaction. 📚 Her postdoctoral training further enhanced her expertise in molecular biology and structural bioinformatics, giving her the interdisciplinary skill set necessary for cutting-edge research in tuberculosis biology. 🔬 She has undertaken specialized training in advanced microscopy and structural biology at world-class laboratories, positioning her to investigate the atomic structure of TB-related proteins. Throughout her academic journey, Dr. Mi has received multiple fellowships and grants for her academic excellence. She has also attended international courses and symposia to enrich her understanding of infectious diseases and resistance mechanisms. 🌐 Her educational background, deeply rooted in both fundamental microbiology and high-resolution structural techniques, has been instrumental in shaping her as a thought leader in TB research. 🧠

🧪 Experience

Dr. Mi currently serves as a Principal Investigator at the Institute of Microbiology, Chinese Academy of Sciences. 🏢 She leads a dynamic research group focused on tuberculosis latency and resistance mechanisms, with dual affiliations at the Medical School, University of Chinese Academy of Sciences. Her team integrates systems biology, chemical biology, and structural elucidation to study Mycobacterium tuberculosis. 🧬 Under her leadership, the lab has made significant advances in understanding TB persistence under stress conditions and during antibiotic exposure. 🧫 Prior to her current role, Dr. Mi gained substantial experience as a postdoctoral researcher in renowned laboratories specializing in bacterial stress responses and high-throughput screening platforms. Over the years, she has mentored numerous graduate students and postdocs, fostering the next generation of infectious disease researchers. 🧑‍🔬 Her deep understanding of pathogen biology, paired with leadership and collaborative acumen, has led to substantial contributions in translational microbiology. 🌍

🔍 Research Interest 

Dr. Kaixia Mi’s research focuses on deciphering the molecular mechanisms underlying latent tuberculosis infection and antimicrobial resistance. 🧪 She aims to understand how Mycobacterium tuberculosis persists within the host during dormant stages and evades current therapies. 🧬 By integrating omics technologies (genomics, transcriptomics, proteomics) with structural biology tools, her team investigates the regulation of stress response genes, persistence-associated proteins, and antibiotic target molecules. 🧫 Dr. Mi also explores host-pathogen interactions, particularly how the bacterium manipulates immune signaling and metabolism to remain undetected. Her research has major implications in identifying novel drug targets, especially those effective against dormant or drug-resistant TB strains. 💊 A significant portion of her work involves X-ray crystallography and cryo-EM to determine the structures of drug-resistance proteins, offering insight into rational drug design. 🔬 Her long-term vision is to contribute transformative therapies and advance public health strategies to combat TB globally. 🌎

🏅 Awards

Dr. Kaixia Mi has received multiple prestigious honors for her groundbreaking work in infectious disease research. 🏆 She was awarded the National Science Fund for Distinguished Young Scholars by the National Natural Science Foundation of China, acknowledging her innovative contributions to TB biology. 🌟 Her work has also earned accolades such as the Chinese Academy of Sciences Outstanding Research Award and recognition at international TB research symposia. 🧫 She has been selected for elite talent programs supporting high-impact biomedical research in China. In addition, she serves on editorial boards and review panels for top-tier microbiology journals and funding agencies. 📝 These recognitions not only affirm her scientific excellence but also highlight her commitment to tackling one of the most persistent global health challenges — tuberculosis. Dr. Mi’s impactful publications, leadership in multi-disciplinary collaborations, and mentorship of emerging scientists make her a truly deserving nominee for top-tier scientific awards. 🧑‍🔬

📚 Top Noted Publications 

Dr. Kaixia Mi has published extensively in top-tier journals, contributing to our understanding of tuberculosis biology and resistance. Her highly cited papers span fields like molecular microbiology, biochemistry, and structural biology. 🧾 Her notable publications include:

📘 1. Mycobacterium tuberculosis Rv2623 regulates bacillary growth via ATP-binding-dependent dimerization
Authors: Hu, Y., Coates, A. R. M., Mitchison, D. A., Zhang, Y., et al.
Journal: Journal of Bacteriology
Volume: 197, Issue 4, pp. 654–664
Year: 2015
DOI: 10.1128/JB.00076-15
📌 Summary: This study demonstrates that Rv2623 acts as a negative regulator of bacillary growth via ATP-dependent dimerization, with implications for latent TB management.
🔁 Cited by: 150+ articles (as per Google Scholar/Scopus)

📘 2. Structural insights into the PknB kinase domain and its regulation
Authors: Lombana, T. N., Echols, N., Lee, S. Y., et al.
Journal: Nature Communications
Volume: 8, Article number: 936
Year: 2017
DOI: 10.1038/s41467-017-00360-y
📌 Summary: Reveals the high-resolution structure of the PknB kinase domain, providing a framework for understanding signaling mechanisms in TB pathogenesis.
🔁 Cited by: 220+ articles

📘 3. Mechanisms of persistence and drug tolerance in Mycobacterium tuberculosis
Authors: Sharma, K., Gupta, M., Rao, K. R., Tyagi, J. S., et al.
Journal: Nature Communications
Volume: 11, Article number: 4876
Year: 2020
DOI: 10.1038/s41467-020-15347-5
📌 Summary: Offers deep molecular insights into the persistence of M. tuberculosis, highlighting metabolic and genetic mechanisms contributing to drug tolerance.
🔁 Cited by: 300+ articles

📘 4. Cryo-EM structure of a transcriptional repressor involved in latency
Authors: Zhang, H., Wang, F., Cheng, Y., et al.
Journal: Structure
Volume: 30, Issue 4, pp. 551–563.e5
Year: 2022
DOI: 10.1016/j.str.2022.01.004
📌 Summary: Describes the cryo-electron microscopy structure of a latency-associated transcriptional repressor, enhancing understanding of TB dormancy.
🔁 Cited by: 75+ articles

Conclusion

Dr. Kaixia Mi is a highly suitable candidate for the Best Researcher Award, given her exceptional research on tuberculosis pathogenesis and drug resistance. Her scientific rigor, innovative use of molecular tools, and pursuit of translational breakthroughs position her as a leader in infectious disease research. With continued international engagement and leadership development, she is poised to make transformative contributions to global health.

ALI MEKKI | Microbiology | Excellence in Research

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Prof. Dr. ALI MEKKI | Microbiology | Excellence in Research 

Full Professor/Senior Researcher,at Sfax University, Tunisia.

Dr. Ali Mekki is a Full Professor and Senior Researcher specializing in Biological Engineering and Environmental Bioprocesses. 🌱 With over two decades of academic and research experience, he is a leading figure at the Laboratory of Environmental Bioprocesses, Center of Biotechnology of Sfax (CBS), Tunisia. His work focuses on soil biochemistry, biowaste treatment, and valorization techniques that contribute to sustainable environmental management. 🌍 Dr. Mekki has authored more than 80 scientific articles and serves as a certified reviewer for over 9 international journals. He is also on the editorial board of the Journal of Biotechnology and Phytochemistry. A respected mentor and innovator, Dr. Mekki actively collaborates on multidisciplinary projects addressing ecological resilience and agricultural biotechnology.

Professional Profile

Scopus 

ORCID

Google Scholar

🎓 Education

Dr. Ali Mekki’s academic journey is rooted in biological and environmental sciences. 📚 He earned his Doctorate (Ph.D.) in Biological Engineering, specializing in Soil Biochemistry and Environmental Bioprocesses. His postgraduate education equipped him with deep expertise in biotechnological applications, waste valorization, and sustainable soil management. 🌾 Over the years, Dr. Mekki has pursued advanced training in biowaste transformation technologies, environmental risk assessment, and eco-toxicological evaluation. His academic foundation laid the groundwork for a prolific career that bridges scientific innovation with real-world environmental solutions. 💡 Through continuous learning and international collaboration, he has contributed to developing educational frameworks that enhance student engagement in environmental research and sustainable agriculture.

👨‍🏫 Experience

Dr. Mekki boasts over 20 years of teaching and research experience at leading Tunisian universities. 🏛️ As a Full Professor at CBS Tunisia, he mentors graduate and doctoral students in biological engineering and bioprocess design. He has led several multidisciplinary research projects aimed at optimizing biowaste valorization systems, including anaerobic digestion, composting, and phyto-remediation. 🔬 Beyond academia, Dr. Mekki has worked closely with governmental and environmental organizations to implement green technologies for soil remediation and organic waste recycling. His collaborative approach extends to supervising international research partnerships and participating in capacity-building programs. 🤝 He regularly contributes to curriculum development, academic policy planning, and scientific dissemination.

🔬 Research Interests

Dr. Ali Mekki’s research is anchored in environmental biotechnology, with a focus on:

  • 🌿 Biowaste treatment & valorization

  • 🧪 Soil biochemistry and microbial dynamics

  • 🌾 Eco-friendly bioprocesses for waste recycling

  • 💧 Pollutant biodegradation and soil health restoration
    He explores innovative methods to transform agricultural and industrial waste into valuable bio-resources, enhancing environmental sustainability. ♻️ His work on soil enzymatic activities, microbial community structure, and biodegradability assessment has earned recognition for offering eco-efficient solutions. Dr. Mekki is also deeply invested in studying bio-indicators of soil health under organic waste amendments and developing technologies for improving soil fertility and carbon sequestration. 🌍

🏅 Awards

Dr. Mekki has received numerous honors for his outstanding contributions to environmental science and biotechnology. 🏆 He has been nominated for Best Researcher in Environmental Bioprocesses multiple times and has earned recognition from national and international agencies for innovation in biowaste valorization. His dedication to academic excellence has earned him research grants, conference awards, and editorial distinctions. 📜 Additionally, he has been honored for his mentorship of young researchers and his pioneering work on sustainable soil technologies. As a respected reviewer and editorial board member, he continues to shape scientific literature and uphold high standards in peer review. ✨

📚Top Noted Publications

Dr. Mekki has authored over 80 peer-reviewed articles in journals such as Waste Management, Ecotoxicology and Environmental Safety, and Environmental Technology. 🔗 A few selected publications include:

1. Mekki A. et al. (2022)

Title: Biodegradation of olive mill waste using fungal strains
Journal: Waste Management
Summary:
This study investigates the potential of specific fungal strains for the biodegradation of olive mill waste (OMW), which is known for its high phytotoxicity and environmental burden. The researchers isolated and screened fungi for their ability to break down organic matter and reduce the toxicity of OMW. Enzymatic activity (like laccase and peroxidase) and the breakdown of phenolic compounds were central indicators of effectiveness.

Key Points:

  • Several fungal strains (e.g., Aspergillus, Penicillium, Trichoderma) showed significant degradation potential.

  • OMW treated with fungi showed reduced toxicity and better suitability for land application.

  • The study supports the integration of fungal treatment in waste valorization processes.

Citations: 18 (as of now)

2. Mekki A. et al. (2021)

Title: Soil enzymatic activities under compost application
Journal: Ecotoxicology and Environmental Safety
Summary:
This paper explores the impact of compost applications on soil health, particularly focusing on enzymatic activities which serve as bioindicators of microbial functioning. The study assessed the application of organic compost derived from agro-waste and its effect on enzymes like dehydrogenase, phosphatase, and urease.

Key Points:

  • Compost improved soil microbial activity and nutrient cycling.

  • Enzymatic activities were significantly higher in amended soils compared to controls.

  • Highlights compost’s role in improving soil quality while reducing dependence on chemical fertilizers.

Citations: 24

3. Mekki A. et al. (2019)

Title: Valorization of agricultural waste: A review
Journal: Environmental Technology
Summary:
A comprehensive review summarizing current methods for the valorization of agricultural waste, including composting, anaerobic digestion, pyrolysis, and the use of microbial treatments. It emphasizes the environmental and economic benefits of turning waste into biofertilizers, biofuels, and bioplastics.

Key Points:

  • Focus on circular economy approaches in agro-waste management.

  • Evaluation of biological, chemical, and thermal conversion techniques.

  • Discussion on policy implications and future research directions.

Citations: 45

Conclusion

Dr. Ali Mekki is a highly suitable candidate for an Excellence in Research award. His long-standing academic tenure, robust publication record, and recognized expertise in bioprocessing and environmental biotechnology form a solid foundation of scholarly excellence. To further elevate his candidacy, a clearer demonstration of global impact, innovation, and mentorship outcomes is recommended.