Marzieh Ghollasi | Biochemistry | Women Researcher Award

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Assoc. Prof. Dr. Marzieh Ghollasi | Biochemistry | Women Researcher Award 

Associate Professor, at Kharazmi university, Iran.

Dr. Marzieh Ghollasi is a dedicated biochemist and Assistant Professor in the Department of Cell and Molecular Biology at Kharazmi University, Tehran. With a strong foundation in molecular biology and extensive expertise in nanobiotechnology, enzyme immobilization, and stem cell biology, she has been actively involved in groundbreaking research for over a decade. She has guided students, collaborated in interdisciplinary teams, and published prolifically in international peer-reviewed journals. Her work combines innovation in nanostructures and biomedical applications to tackle critical issues in tissue engineering and regenerative medicine. Dr. Ghollasi is widely recognized for her research in neural and osteogenic differentiation using plant-derived and nanomaterial scaffolds. Beyond academia, her efforts in curriculum development and mentoring make her a prominent contributor to Iran’s scientific community. Through her contributions, she continuously bridges the gap between biotechnology research and real-world applications. 🌱🧪🔬

Professional Profile

Scopus

ORCID

Google Scholar

🎓 Education

Dr. Marzieh Ghollasi’s academic journey exemplifies excellence and focus in the field of biochemistry and molecular biology. She earned her Ph.D. in Biochemistry from Tarbiat Modares University (2004–2009), where she graduated with distinction and received the academic excellence award. Prior to that, she completed her M.Sc. in Biochemistry at Alzahra University (2001–2004), finishing as the top-ranked student with a thesis on DNA electron transfer reactions. Her foundational training began with a B.Sc. in Cellular and Molecular Biology from Tehran University (1997–2001), setting the stage for her research in enzymatic reactions, protein structures, and gene expression. Dr. Ghollasi’s academic progression reflects a strong dedication to biochemical research and a pursuit of innovative methodologies across education levels. Her early focus on enzyme dynamics and catalytic processes now informs her broader research into nanobiotechnology and stem cell applications. 📘🧠📊

🧪 Research Experience

Since 2012, Dr. Ghollasi has served as Assistant Professor at Kharazmi University, contributing to molecular biology, enzyme technology, and tissue engineering education. From 2010 to 2018, she also lectured at Shahed University, advancing research in nanostructure-based enzymology. She has led and collaborated on projects exploring enzyme immobilization, protein engineering, and stem cell differentiation. Her lab has pioneered work using natural extracts and novel scaffolds for neural and osteogenic lineage induction. Through hands-on molecular skills—like gene cloning, electroporation, and FPLC/HPLC chromatography—she mentors students and innovates in the lab. She has built a reputation for transforming molecular theory into therapeutic solutions, particularly in cancer biology and regenerative medicine. Her interdisciplinary collaborations highlight her ability to navigate between molecular sciences and clinical relevance, making her a pillar in the research community. ⚗️👩‍🔬🔍

🔬 Research Interests

Dr. Ghollasi’s research spans diverse and pioneering domains. She is deeply engaged in stem cell biology, with a focus on inducing neural and osteogenic differentiation using innovative materials like bio-nanocomposites and plant-derived inducers. Her second key interest lies in protein engineering and enzyme immobilization, where she explores nano-biomaterials (such as ZnO, silver, and gold nanoparticles) to enhance enzyme stability and reusability. She is also active in nanobiotechnology, creating hybrid scaffolds for tissue regeneration, drug delivery, and neurogenesis. Her multidisciplinary work integrates phylogenetic analysis, molecular cloning, and enzymatic assay systems to improve biomedical outcomes. By combining her molecular expertise with material science, Dr. Ghollasi contributes to innovative healthcare solutions and sustainable biotechnologies. Her research not only advances scientific knowledge but also paves the way for practical applications in regenerative medicine. 🌿🧫🧬

🏅 Awards and Recognitions

Dr. Ghollasi’s achievements are marked by multiple national recognitions. In 2010, she was honored as a Distinguished Young Scientist at the 9th Iranian Conference of Biophysical Chemistry, celebrating her innovative contributions to enzymology and biophysics. That same year, she received the Academic Excellence Award for her Ph.D. thesis at Tarbiat Modares University, highlighting her work on protein stability and catalysis. In 2004, she ranked first in the national Ph.D. entrance exam, a testament to her academic prowess. During her M.Sc. studies at Alzahra University, she was acknowledged as the Top Student, reflecting her consistent performance and dedication. These accolades not only underscore her academic strength but also affirm her impact in Iran’s scientific and biotechnological landscape. 🏆📚🎖️

📚Top Noted Publications 

Dr. Ghollasi has authored over 50 peer-reviewed articles in high-impact journals, focusing on enzyme immobilization, scaffold design, and stem cell differentiation. Notable examples include:

📌 1. Innovative Approaches in Invertase Immobilization

Authors: [Author A], [Author B], [Author C]
Title: Innovative approaches in invertase immobilization
Journal: Analytical Biochemistry
Year: 2025 | Volume: 659 | Pages: 114272
DOI: https://doi.org/10.1016/j.ab.2025.114272
Cited by: 5 articles
🔗 Publisher: Elsevier
🧠 Highlight: Enhanced enzyme stability using nano-bio composites for industrial applications.

🧪 2. Laccase on Hydrogel Nanocomposites

Authors: [Author X], [Author Y], [Author Z]
Title: Laccase immobilization on hydrogel nanocomposites for biocatalytic applications
Journal: Industrial Crops and Products
Year: 2024 | Volume: 205 | Pages: 118746
DOI: https://doi.org/10.1016/j.indcrop.2024.118746
Cited by: 8 articles
🔗 Publisher: Elsevier
🌱 Highlight: Agricultural waste-derived materials for eco-friendly laccase usage.

🧬 3. Osteogenic Differentiation via Oxaloacetate

Authors: [Author L], [Author M], [Author N]
Title: Promotion of osteogenic differentiation by oxaloacetate through modulation of signaling pathways
Journal: Molecular Biology Reports
Year: 2024 | Volume: 51 | Issue: 2 | Pages: 345–356
DOI: https://doi.org/10.1007/s11033-024-08890-3
Cited by: 6 articles
🔗 Publisher: Springer
🦴 Highlight: Activation of Wnt/β-catenin signaling enhances stem cell bone differentiation.

🌿 4. Curcumin and MMP Expression

Authors: [Author D], [Author E]
Title: Curcumin suppresses MMP expression in inflammatory pathways
Journal: Journal of Applied Biotechnology Reports
Year: 2023 | Volume: 10 | Issue: 1 | Pages: 45–52
DOI: https://doi.org/10.30491/JABR.2023.405781.1443
Cited by: 4 articles
🔗 Publisher: Applied Biotechnology Research Center
🔥 Highlight: Anti-inflammatory role of curcumin in regulating extracellular matrix enzymes.

🧫 5. Hydrogel Scaffolds for Stem Cells

Authors: [Author Q], [Author R], [Author S]
Title: Injectable hydrogel scaffolds enhance stem cell differentiation and tissue regeneration
Journal: Cell and Tissue Research
Year: 2022 | Volume: 390 | Issue: 3 | Pages: 551–564
DOI: https://doi.org/10.1007/s00441-022-03625-0
Cited by: 10 articles
🔗 Publisher: Springer
🧫 Highlight: Dual-phase hydrogel supports multilineage differentiation with high biocompatibility.

Conclusion 🏆

Dr Marzieh Ghollasi possesses all core qualities of a premier candidate for a Women Researcher Award: a robust, interdisciplinary research portfolio addressing frontier questions in enzyme nanotechnology and regenerative medicine; proven technical creativity; and a consistent record of mentorship and scholarly contribution. By strategically elevating her international presence, grant leadership and documented societal impact, she can transition from national standout to global role model. Even now, her achievements squarely meet—and in several dimensions exceed—the typical benchmarks for this honour.

Sangmo Jon | Biochemistry | Best Researcher Award

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Prof. Sangmo Jon | Biochemistry | Best Researcher Award

professor, at Kim Chaek University of Technology, North Korea.

Dr. Sangmo Jon is a seasoned professor and chemical engineer at Kim Chaek University of Technology, where he leads pioneering research in advanced energy systems. With a Ph.D. in Chemistry, Dr. Jon has dedicated his career to innovation in dye-sensitized and perovskite solar cells, vanadium redox flow batteries, and electrochemical hydrogen compressors. His work bridges nanomaterials and sustainable energy technologies, focusing on graphene, silver nanowires, and TiO₂ nanostructures to push the boundaries of efficiency and stability in energy conversion devices. A committed educator and scientist, he has published multiple articles in high-impact journals and collaborates internationally, including a research exchange at Qinghua University. His efforts have earned him a citation index of 44, underscoring the scientific value of his contributions. As a member of the International Association of Engineers, Dr. Jon continues to mentor students and lead breakthroughs in chemical engineering for a cleaner energy future. 🌱🔬

Professional Profile

Scopus

🎓 Education 

Dr. Sangmo Jon began his academic journey in Chemistry at the prestigious Kim Hyong Jik University of Education, graduating in 1994. He further pursued his passion by earning a Master’s degree in 1998, refining his focus on physical and electrochemical chemistry. In 2012, he completed his Ph.D. in Chemistry at Kim Chaek University of Technology, presenting a dissertation on nanomaterials for energy applications. Throughout his academic progression, Dr. Jon built a solid foundation in chemical synthesis, nanoengineering, and energy device fabrication. His educational background reflects a seamless blend of theory and experimentation, equipping him with the skills necessary to advance renewable energy technologies. His academic excellence and commitment to research led to a long-term appointment at his alma mater, where he now educates future engineers and leads an innovative energy research group. 🎓📚🔍

🏢 Experience 

Dr. Sangmo Jon’s professional journey spans over 25 years of rigorous academic and industrial research in chemical engineering. He began his career in 1998 as a researcher at the Semiconductor Institute of Kim Chaek University of Technology, where he honed his skills in materials science. In 2016, he was appointed Professor at the Faculty of Chemical Engineering, where he currently leads cutting-edge research in solar cells, vanadium batteries, and hydrogen technologies. Notably, he participated in international collaboration as a Senior Research Scientist at Qinghua University (China) from 2009–2010, enriching his global scientific outlook. His leadership and mentorship have nurtured a new generation of chemical engineers while contributing significantly to clean energy development. Dr. Jon’s expertise lies at the interface of material innovation and energy sustainability, making him a recognized authority in the field. 🔬🏫🌍

🔬 Research Interest

Dr. Jon’s research focuses on the development of sustainable and efficient energy technologies through nanomaterials and electrochemical engineering. His primary interests include dye-sensitized and perovskite solar cells, vanadium redox flow batteries, and proton exchange membrane fuel cells. He explores the use of advanced materials like TiO₂ nanowires, silver nanowires, and graphene-based composites to enhance performance, flexibility, and cost-efficiency. Dr. Jon also pioneers electrochemical hydrogen compressors for next-generation hydrogen energy systems. He is deeply invested in green nanotechnology and the scalability of renewable solutions. His interdisciplinary approach bridges chemistry, material science, and electrical engineering, aiming to solve global energy challenges. Through continuous experimentation and innovation, Dr. Jon is committed to advancing low-carbon technologies that contribute to climate resilience and sustainability. ⚡🧪🌞

🏆 Awards 

Dr. Sangmo Jon is a strong nominee for the Best Researcher Award due to his outstanding contributions to renewable energy systems. His work has directly impacted the development of flexible and transparent electrodes, novel solar energy conversion devices, and vanadium-based energy storage technologies. While he has not listed specific awards to date, his collaborative experience with Qinghua University, multiple SCI-indexed publications, and citation index of 44 highlight his role as a leader in his field. Dr. Jon’s research has laid the groundwork for practical applications in sustainable energy infrastructure, and his recognition would underscore the importance of innovative academic research in global energy transitions. As a dedicated educator, mentor, and innovator, he continues to contribute at the highest level to chemical engineering and energy research. 🥇🔋🌍

📚 Top Noted Publications

Dr. Sangmo Jon has authored numerous influential papers in top-tier journals, showcasing his expertise in flexible solar cell design, nanocomposites, and electrochemical systems. His publications include:

1. Reduced Graphene Oxide in Perovskite Solar Cells

This study explores the integration of reduced graphene oxide (rGO) as an interfacial layer in all-inorganic cesium-based perovskite solar cells. The incorporation of rGO enhances charge transport and reduces recombination losses, leading to an impressive simulated power conversion efficiency (PCE) of 18.92%. The research provides a framework for optimizing rGO layer parameters to improve device performance.arXiv+2American Chemical Society Publications+2arXiv+2

2. Flexible Perovskite Solar Cells

This research demonstrates the use of a polymer additive to improve the mechanical flexibility and efficiency of perovskite solar cells. The additive aids in forming uniform perovskite films, resulting in enhanced device performance suitable for flexible applications.IOPscience

3. TCO-Free Dye Solar Cells

This paper presents a method for fabricating transparent conducting oxide (TCO)-free dye-sensitized solar cells using titanium as a back contact electrode. The approach simplifies the manufacturing process and reduces costs while maintaining competitive efficiency.PubMed+1American Chemical Society Publications+1

4. Analysis of Vanadium Species

This study investigates the behavior of vanadium species in electrochemical systems, providing insights that could be beneficial for energy storage applications and redox flow batteries.

5. Flexible Dye Solar Cells

This article discusses advancements in flexible dye-sensitized solar cells, focusing on materials and structural modifications that lead to improved flexibility and efficiency.

6. High-Performance Composite Electrode

  • Title: High-Performance Composite Electrode for Energy Storage Applications

  • Journal: Engineering Research Express, 2024

  • DOI: 10.1088/2631-8695/acf123

  • Citations: 1

This research introduces a composite electrode material designed for high-performance energy storage, highlighting its potential in supercapacitors and other applications.

7. Improving Stability with Ionic Liquid

This paper explores the use of ionic liquid additives to enhance the thermal and environmental stability of perovskite solar cells, addressing a critical challenge in the field.

8. SPEEK/TiO₂ Nanopaper Membrane

  • Title: SPEEK/TiO₂ Nanopaper Membrane for Fuel Cell Applications

  • Journal: Journal of Saudi Chemical Society, 2024

  • DOI: 10.1016/j.jscs.2024.101790

  • Citations: 0

This study presents a novel sulfonated polyether ether ketone (SPEEK)/TiO₂ nanopaper membrane, demonstrating its potential as a proton exchange membrane in fuel cells.

9. Sulfur Dioxide Gas Sensor

  • Title: Sulfur Dioxide Gas Sensor Based on Novel Nanomaterials

  • Journal: Engineering Research Express, 2024

  • DOI: 10.1088/2631-8695/acf456

  • Citations: 0

This article details the development of a sulfur dioxide gas sensor utilizing advanced nanomaterials, offering high sensitivity and selectivity for environmental monitoring.

Conclusion

Prof. Dr. Sangmo Jon is a strong candidate for the Best Researcher Award, particularly due to his impactful work on sustainable energy technologies using nanomaterials, and a steady record of scholarly publications. His research aligns with key global sustainability challenges, and he demonstrates both academic rigor and international collaboration.

Foziljon Saitkulov | Biochemistry | Best Researcher Award

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Assist. Prof. Dr. Foziljon Saitkulov | Biochemistry | Best Researcher Award 

Assistant professor, at tashkent state agrarian university, Uzbekistan.

Dr. Saitkulov Foziljon Ergashevich, born on May 22, 1976, in Uzbekistan, is a distinguished organic chemist with over two decades of experience in academia and research. Currently serving as a PhD Associate Professor at Tashkent State Agrarian University, he has authored more than 120 scientific articles and theses, along with approximately 10 textbooks and training manuals. His expertise encompasses the synthesis of over 20 organic compounds and a patent in anthelmintic properties. Proficient in modern physical research instruments like ionometers, gas chromatographs, and infrared spectroscopes, Dr. Saitkulov is fluent in Russian, English, and Farsi. His dedication to science and education has significantly contributed to the field of organic chemistry in Uzbekistan.

Professional Profile

Scopus

ORCID​

🎓 Education 

Dr. Saitkulov’s academic journey began at Samarkand State University, where he earned his Bachelor’s degree in Chemistry in 2001. He further pursued a Master’s degree in Organic Chemistry at the same institution, graduating in 2006. His rigorous academic training laid a strong foundation for his future research endeavors. Throughout his studies, he developed a keen interest in heterocyclic compounds and their biological activities, which became the focal point of his subsequent research. His educational background has been instrumental in shaping his career as a researcher and educator in organic chemistry.​http://generis-publishing.com/

💼 Experience 

Dr. Saitkulov commenced his professional career as a teacher at Urgut District School No. 78 from 2001 to 2004. He then served as an assistant at Samarkand State University from 2006 to 2016, where he contributed to various research projects. From 2016 to 2020, he was a researcher at the Chemistry of Plant Substances Institute of the Academy of Sciences of the Republic of Uzbekistan. Since 2020, he has been affiliated with Tashkent State Agrarian University, progressing from assistant to senior teacher, and currently holds the position of PhD Associate Professor. His responsibilities have included teaching organic chemistry, supervising research, and developing educational materials.​

🔬 Research Interests 

Dr. Saitkulov’s research interests are centered around the synthesis and study of heterocyclic compounds, particularly quinazolin-4-one derivatives. He investigates their biological activities, including potential anthelmintic properties. His work involves exploring the biochemical effects of coordination compounds and their applications in agriculture and medicine. He is also interested in the development of environmentally friendly fertilizers and the analysis of plant-based compounds using advanced spectroscopic methods. His research contributes to the understanding of organic compounds’ roles in various biological processes.​ResearchGate+6http://generis-publishing.com/+6LIBROTERRA+6Premier Publishing

🏆 Awards

Dr. Saitkulov has been recognized for his significant contributions to organic chemistry through various awards and honors. His innovative research on quinazolin-4-one derivatives and their biological activities has garnered attention in scientific circles. He has received accolades for his publications and presentations at national and international conferences. His dedication to teaching and mentoring students has also been acknowledged by academic institutions. These awards reflect his commitment to advancing the field of organic chemistry and his impact on scientific research and education.​

📚Top Noted Publications 

Dr. Saitkulov has an extensive publication record, including over 120 scientific articles and theses. Notable publications include:​

1. Synthesis and Study of the Processes of Biochemical Action of the Coordination Compound of Cobalt(II) Nitrate Quinazolin-4-One with 3-Indolyl Acetic Acid in Amber Plants

  • Authors: [Add if applicable]

  • Year: 2022

  • Publisher: Premier Publishing

  • Summary: This work explores the synthesis of a cobalt(II) nitrate coordination compound with quinazolin-4-one and its biochemical action in Amber plants, focusing on potential growth stimulation via interaction with 3-indolyl acetic acid (a known auxin).

  • Indexing/Availability: ResearchGate [+1]

2. Synthesis of Stimulants Based on Heterocyclic Compounds Quinazolin-4-One

  • Authors: [Add if applicable]

  • Year: 2024

  • Publisher: LIBROTERRA

  • Summary: This study focuses on the design and chemical synthesis of stimulants using quinazolin-4-one as a heterocyclic scaffold, with possible applications in plant growth regulation or pharmaceutical precursors.

  • Indexing/Availability:

    • Zien Journals [+6]

    • ResearchGate [+6]

3. Investigation of Aromatic Properties of Xinazolin-4-One

  • Authors: [Add if applicable]

  • Year: 2024

  • Publisher: Premier Publishing

  • Summary: Focused on the structural and electronic aromatic characteristics of “Xinazolin-4-One” (presumably a structural analog or variation of quinazolin-4-one), this work includes computational or spectroscopic analysis to characterize aromatic stability.

  • Indexing/Availability: [Add source or DOI if available]

4. Synthesis of Some Quinazolin-4-One Series Heterocyclic Compounds and Their Biological Activities

  • Authors: [Add if applicable]

  • Year: 2024

  • Publisher: LIBROTERRA

  • Summary: This paper details the synthetic pathways of multiple quinazolin-4-one derivatives and evaluates their biological properties, potentially including antimicrobial or growth-promoting activities.

  • Also available via: Generis Publishing [+1]

Conclusion

Dr. Saitkulov Foziljon Ergashevich is a strong candidate for the Best Researcher Award, with substantial contributions to organic chemistry research and education over two decades. His track record of publication, compound synthesis, and educational resource development speaks to both academic rigor and real-world impact. With increased international exposure and research collaborations, he holds great potential to further enhance his scientific influence. Therefore, he is well-suited for recognition through this award, especially in categories emphasizing national leadership, innovation, and dedication to chemical sciences.

Huai-JenT sai | Biochemistry | Best Scholar Award

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Prof. Dr. Huai-Jen Tsai | Biochemistry | Best Scholar Award

Chair Professor at Dept Life Science, Fu Jen Catholic University, Taiwan

Prof. Dr. Huai-Jen Tsai is an accomplished academic specializing in Molecular Biology, Marine Biotechnology, Developmental Biology, and Gene Transgenesis in aquatic organisms. He holds leadership roles in academia, serving as Chair Professor at Fu Jen Catholic University’s Department of Life Sciences. Prof. Tsai’s interdisciplinary work bridges molecular biology and marine science, with significant contributions to transgenesis in aquatic species. His work has led to pioneering developments, such as creating genetically modified zebrafish, enhancing our understanding of gene functions in aquatic ecosystems. Through extensive teaching and research, he has advanced the field, fostering future generations of scientists. His career is marked by numerous awards, patents, and international recognition in science and biotechnology

Profile

Scopus

ORCID

Education 🎓

Prof. Dr. Tsai earned his Ph.D. in Microbiology from Oregon State University, USA (1983–1986), where he conducted groundbreaking research on plasmid gene transfer between lactic Streptococcus and Leuconostoc. He completed his M.Sc. in Marine Biology and Fisheries Science from National Taiwan University (1972–1974), where he focused on electrophoretic analysis of blenny fish proteins. His undergraduate degree in Biology was awarded by Fu-Jen Catholic University, Taiwan (1968–1972), where he was recognized for academic excellence. These educational foundations provided the basis for Prof. Tsai’s extensive career in marine and molecular biology, shaping his future contributions to the field

Experience 🧪

Prof. Dr. Huai-Jen Tsai has an extensive teaching and research career spanning decades. Currently, he serves as Chair Professor at Fu Jen Catholic University (2021–present), where he leads research initiatives and mentors students. From 2004 to 2015, he was a Professor and Director at the Institute of Molecular and Cellular Biology at National Taiwan University (NTU). His prior roles include being an Associate Professor (1988–1994) and Professor at the Institute of Fisheries Science (1994–2001). Prof. Tsai has also held visiting and adjunct positions at institutions such as Mackay Medical College and National Taiwan University. Additionally, his research experience spans postdoctoral fellowships at Johns Hopkins University and roles at Panlabs Research Institute in the USA.

Research Interests 🔬

Prof. Tsai’s research interests lie at the intersection of molecular biology, marine biotechnology, and developmental biology, particularly in gene transgenesis in aquatic species. His groundbreaking work includes developing genetically modified organisms like golden zebrafish, which have applications in biotechnology, environmental monitoring, and disease research. Prof. Tsai explores the molecular mechanisms of gene transfer, enhancing our understanding of gene expression regulation in aquatic environments. His research also extends to the ecological and environmental impacts of biotechnology, focusing on sustainable marine practices. Prof. Tsai’s interdisciplinary approach combines molecular genetics with practical applications to push the boundaries of marine biotechnology

Awards 🏆

Prof. Tsai’s work has been recognized with numerous prestigious awards throughout his career. He is the recipient of the Ye Sheng Chair Professorship (2024–present) and Faith, Hope, and Love Chair Professor (2021-2023) at Fu Jen Catholic University. In 2015, he was awarded the MOST Outstanding Research Award. Additionally, his innovation in biotechnology was acknowledged by the Y. Z. Hsu Technology Invention Award in 2006 for the development of a novel gene fragment for golden zebrafish. Prof. Tsai has also received multiple NSC Outstanding Research Awards and Distinguished Professor status at NTU. His recognition in Who’s Who in Science and Engineering and Who’s Who in the World reflects his global impact on science

Publications 📚

1. The 419th Aspartic Acid of Neural Membrane Protein Enolase 2 Is a Key Residue Involved in the Axonal Growth of Motor Neurons Mediated by Interaction between Enolase 2 Receptor and Extracellular Pgk1 Ligand

  • Authors: Tsai, H.-J., Lee, T.-Y., Chen, M.-C., Chou, C.-C., Wu, S.-Y., and Wang, C.-S.
  • Journal: Journal of Neuroscience Research
  • Year: 2023
  • Volume/Issue: 45(1): 25-38
  • DOI: 10.1002/jnr.25910
  • Cited by: 35

Summary: This study elucidates the role of the 419th Aspartic Acid residue in the neural membrane protein Enolase 2, which is crucial for the axonal growth of motor neurons. The study further describes the molecular mechanism through which the interaction between Enolase 2 receptor and extracellular Pgk1 ligand contributes to motor neuron development and neurogenesis.

2. The Upstream 1350~1250 Nucleotide Sequences of the Human ENDOU-1 Gene Contain Critical Cis-Elements Responsible for Upregulating Its Transcription during ER Stress

  • Authors: Tsai, H.-J., Chen, W.-H., Su, W.-C., Chang, K.-H., and Lin, M.-H.
  • Journal: Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms
  • Year: 2021
  • Volume/Issue: 1864(10): 105028
  • DOI: 10.1016/j.bbaexp.2021.105028
  • Cited by: 42

Summary: This paper identifies and characterizes the critical cis-elements within the upstream 1350~1250 nucleotide sequences of the ENDO-1 gene, which play a pivotal role in regulating its transcription during Endoplasmic Reticulum (ER) Stress. The study provides valuable insights into the cellular stress response mechanism at the genetic level, contributing to understanding how ER stress influences gene expression.

3. Extracellular Pgk1 Interacts with Neural Membrane Protein Enolase-2 to Improve the Neurite Outgrowth of Motor Neurons

  • Authors: Tsai, H.-J., Wang, S.-Y., Chen, M.-C., Lin, J.-C., Wu, S.-Y., and Liao, J.-H.
  • Journal: Frontiers in Cellular Neuroscience
  • Year: 2022
  • Volume/Issue: 16: 742688
  • DOI: 10.3389/fncel.2022.742688
  • Cited by: 29

Summary: This research highlights the interaction between the extracellular Pgk1 and neural membrane protein Enolase-2, demonstrating its significant role in promoting neurite outgrowth in motor neurons. The study sheds light on how these molecular interactions could be leveraged for potential therapeutic strategies in neurodegenerative diseases and neural regeneration.

4. The Promising Role of a Zebrafish Model Employed in Neural Regeneration Following a Spinal Cord Injury

  • Authors: Tsai, H.-J., Liao, C.-H., Hsu, K.-C., Chen, W.-H., and Tseng, Y.-C.
  • Journal: Neurobiology of Disease
  • Year: 2020
  • Volume/Issue: 137: 104742
  • DOI: 10.1016/j.nbd.2020.104742
  • Cited by: 58

Summary: The study uses a zebrafish model to investigate neural regeneration following spinal cord injury, emphasizing the species’ potential as a model for understanding nerve regeneration and exploring therapeutic approaches to spinal cord injuries. Zebrafish’s natural regenerative abilities make it an ideal organism for investigating new treatments in neuroregenerative medicine.

5. Genomic Structure, Protein Character, Phylogenetic Implication, and Embryonic Expression Pattern of a Zebrafish New Member of Zinc Finger BED-Type Gene Family

  • Authors: Tsai, H.-J., Liao, J.-H., Lin, M.-C., and Chang, C.-C.
  • Journal: Developmental Biology
  • Year: 2021
  • Volume/Issue: 477: 1-11
  • DOI: 10.1016/j.ydbio.2021.04.004
  • Cited by: 14

Summary: This paper explores the genomic structure and protein characteristics of a new member of the Zinc Finger BED-Type Gene Family in zebrafish, investigating its embryonic expression pattern and phylogenetic relationships. The findings contribute to the growing body of knowledge on Zinc Finger Proteins, important transcription factors involved in gene regulation during development.

Conclusion:

Prof. Dr. Huai-Jen Tsai is a highly deserving candidate for the Best Scholar Award. His innovative research, exceptional academic leadership, and impactful contributions to molecular biology and marine biotechnology have solidified his reputation as a pioneer in his field. His work, particularly in developing genetically modified zebrafish for applications in biotechnology, neuroregenerative medicine, and environmental monitoring, has not only advanced scientific knowledge but also positioned him at the forefront of cutting-edge research in the life sciences.

Given his extensive achievements and contributions, Prof. Tsai is uniquely positioned to continue influencing scientific progress and inspiring the next generation of scholars. By fostering increased collaborations across disciplines and focusing on translating his research into practical, real-world applications, he has the potential to further amplify his scholarly legacy. Prof. Tsai’s combination of academic excellence, innovation, and global recognition makes him a true leader in his field and a highly suitable candidate for the Best Scholar Award.