jinghui xie | Molecular Biology | Best Researcher Award

Published on by Molecular Biologist

Mr. jinghui xie | Molecular Biology | Best Researcher Award 

Associate professor, at xinjiang medical university, China.

Dr. Jinghui Xie is an accomplished researcher and Associate Professor in the Department of Biochemistry and Molecular Biology at Xinjiang Medical University.  He holds a Doctor of Science (Ph.D.) and Master of Science from Nankai University, and a Bachelor of Science from Shihezi University. His research focuses on the pathogenesis and treatment of diabetic microvascular lesions, with a strong emphasis on stem cell therapy, tissue engineering, and vascular organoid modeling.  Dr. Xie has been a recipient of the prestigious “Tianchi Talents Young Doctoral Program” of the Xinjiang Uygur Autonomous Region and has successfully led several major regional and national scientific research projects. 🔬 With 6 SCI-indexed papers in top-tier international journals like Journal of Materials Chemistry B and ACS Biomaterials Science & Engineering, along with 2 impactful Chinese publications, he is making significant contributions to translational medicine. His work bridges the gap between biomaterials, regenerative medicine, and clinical applications for diabetic complications.

Professional Profile

Google Scholar

🎓 Education

Dr. Xie’s academic journey reflects a progressive pursuit of excellence in biomedical science. 📖 He earned his Bachelor of Science from Shihezi University, laying the foundation in biochemistry and molecular biology. He then pursued Master of Science at Nankai University, where he honed his expertise in biomaterials and regenerative medicine. 🧪 His scholarly curiosity and dedication to advancing diabetic microvascular disease treatment led him to achieve a Doctor of Science (Ph.D.) in Biochemistry and Molecular Biology at Nankai University. During his Ph.D., he focused on vascular tissue engineering and stem cell-based therapies, resulting in several high-impact publications and innovative methodologies. 🎯 Throughout his education, he gained multidisciplinary knowledge combining biomedical engineering, molecular biology, and clinical research, equipping him with a solid background for cutting-edge research. 🎓💡

💼 Experience

Dr. Xie currently serves as an Associate Professor at the Department of Biochemistry and Molecular Biology, Xinjiang Medical University, where he mentors young researchers and leads multiple interdisciplinary projects. 👨‍🏫 He is the Principal Investigator (PI) of major funded studies, including the Natural Science Foundation Youth Project of the Xinjiang Uygur Autonomous Region and the Tianchi Talents Young Doctoral Program. 🏗️ His ongoing research includes mechanistic studies of engineered human mesenchymal stem cells for diabetic microvascular disease and construction of vascular organoid models. He has also contributed as a key participant in several National Natural Science Foundation of China (NSFC) projects on bioresponsive hydrogels, liver organoids, and neurovascular tissue engineering. 🔬 Beyond research, Dr. Xie actively contributes to academic development through teaching, curriculum improvement, and editorial roles in medical education journals. 🏅

🔬 Research Interests

Dr. Xie’s research is deeply rooted in regenerative medicine, biomaterials, and vascular biology. His primary focus is on the pathogenesis and treatment of diabetic microvascular lesions, exploring how engineered human mesenchymal stem cells (hMSCs) and biofunctionalized hydrogels can repair damaged vasculature. 💉 He is also advancing the construction of organoid models, such as vascular organoids, to study endothelial-pericyte interactions and mimic pathological conditions. 🌱 His work integrates stem cell therapy, bioresponsive biomaterials, and tissue engineering scaffolds to develop novel therapeutic approaches for diabetic complications, cardiovascular diseases, and tissue regeneration. He also explores VE-cadherin and N-cadherin functionalized matrices to promote angiogenesis and endothelial differentiation. 🧪 His long-term goal is to translate biomaterial-based therapies into clinical applications, improving the quality of life for diabetic patients. 🌟

🏆 Awards & Honors

Dr. Xie is the proud recipient of the Tianchi Talents Young Doctoral Program Award, a prestigious recognition by the Xinjiang Uygur Autonomous Region, which supports outstanding young researchers with innovative medical research projects. 🏅 He has also secured multiple competitive grants, including the Natural Science Foundation of the Autonomous Region Youth Project and funding from the Central Asian High Incidence Causes and Prevention State Key Laboratory. 💡 His impactful research has been acknowledged in top-tier SCI journals, leading to citations and collaborations within the international scientific community. 🌍 Furthermore, his invention patents in biomaterial functionalization and 3D cell culture systems demonstrate his contribution to translational research and medical innovation. 🚀

📚 Top Noted Publications 

Dr. Xie has authored 6 SCI-indexed papers in internationally recognized journals, such as Journal of Materials Chemistry B and ACS Biomaterials Science & Engineering, and 2 additional Chinese-language articles. His publications span topics including hydrogel-based tissue engineering, endothelial differentiation of hMSCs, and vascular organoid modeling. 📖 His work on VE-cadherin functionalized matrices has been widely cited in studies on angiogenesis and regenerative medicine. ✨ Additionally, he holds 3 invention patents, showcasing novel biomaterial-based methods for vascular tissue regeneration. His research contributions have been cited in applied biomaterials, cardiovascular therapy, and diabetes-related tissue engineering studies, reinforcing his influence in the field. 🌐

🔗 Representative Publications with Citation Prompt

📄 1️⃣ Lv C, Li S, Sang M, Cui T, Xie J.
Title: Construction of Microsphere Culture System for Human Mesenchymal Stem Cell Aggregates
Journal: International Journal of Molecular Sciences
Year: 2025, Volume 26, Article 6435
Link: 🔗 Read Here
Citation Context: Frequently cited in organoid culture system research for its innovative approach to MSC aggregate formation.

📄 2️⃣ Jinghui Xie, Xiaoning Li, Yan Zhang, et al.
Title: VE-Cadherin based matrix promoting self-reconstruction of proangiogenic microenvironment
Journal: Journal of Materials Chemistry B
Year: 2021, 9(1), pp. 3357–3370
Link: 🔗 Read Here
Citation Context: Referenced in endothelial differentiation studies exploring angiogenic microenvironments.

📄 3️⃣ Yuanning Lyu, Jinghui Xie, Yang Liu, et al.
Title: Injectable Hyaluronic Acid Hydrogel for Myocardial Repair
Journal: ACS Biomaterials Science & Engineering
Year: 2020, 6(12), pp. 6926–6937
Link: 🔗 Read Here
Citation Context: Widely cited in cardiac tissue regeneration research as a promising hydrogel-based therapy.

📄 4️⃣ Yang Jun, Xie Jinghui, Gao Chao, et al.
Title: VE-cad-Fc Functionalized Hyaluronic Acid Hydrogel
Journal: Journal of Tianjin University
Year: 2019, 52(1), pp. 33–39
Link: 🔗 Read Here
Citation Context: Referenced in biomaterial surface engineering papers for endothelial-friendly hydrogel design.

📄 5️⃣ Chao Gao, Yan Zhang, Jinghui Xie, et al.
Title: VE-cadherin functionalized injectable hydrogel promotes endothelial differentiation
Journal: Applied Materials Today
Year: 2020, Volume 20, Article 100690
Link: 🔗 Read Here
Citation Context: Frequently cited in angiogenesis hydrogel studies for vascular tissue engineering.

📄 6️⃣ Ke Xu, Chuanshun Zhu, Jinghui Xie, et al.
Title: Enhanced Vascularization of PCL Scaffolds through VEGF-Fc
Journal: Journal of Materials Chemistry B
Year: 2018, 6(6), p. 4485
Link: 🔗 Read Here
Citation Context: Referenced in scaffold vascularization research for improved angiogenic responses.

🏆 Conclusion

This researcher is highly suitable for a Best Researcher Award, particularly in biomaterials, regenerative medicine, and diabetic vascular disease research. Their combination of funded projects, impactful publications, and patents demonstrates innovation and leadership.

Partha Sarathi Nial | B-Z DNA transition | Best Researcher Award

Published on by Molecular Biologist

Mr . Partha Sarathi Nial | B-Z DNA transition | Best Researcher Award 

PhD Scholar , CSIR-Institute of Minerals and Materials Technology , India

Partha Sarathi Nial is a dedicated Ph.D. scholar in Biological Science at the CSIR-Institute of Minerals and Materials Technology, Bhubaneswar, India. His research focuses on DNA nanotechnology, specifically on sequence-specific conformational switching in linear and branched DNA structures. With a strong foundation in biotechnology and extensive experience in both academic research and industry, Partha is committed to advancing our understanding of DNA’s structural dynamics and their potential applications in gene regulation and therapeutics.

Profile

Scopus

Strengths for the Award

  1. Advanced Research Focus: Partha Sarathi Nial’s doctoral research on “Sequence-specific conformational switching in linear and branched DNA structures” showcases a high level of expertise in a cutting-edge area of biological science, particularly in DNA nanotechnology and its applications in gene regulation and therapeutic approaches. His focus on B-Z DNA transition and G-Quadruplex formation is not only innovative but also highly relevant to understanding complex biological processes and diseases like cancer and Alzheimer’s.
  2. Publications in High-Impact Journals: Partha has multiple publications in reputed journals with high impact factors, including the Journal of Molecular Liquids and the International Journal of Biological Macromolecules. These publications underline the quality and impact of his research work in the scientific community.
  3. Awards and Recognitions: Partha’s achievements, such as securing the CSIR-NET JRF (AIR-100) in Life Sciences, demonstrate his strong academic foundation and recognition by peers. Being selected for positions in prestigious organizations like Thyrocare Technologies Ltd. further attests to his credibility and potential.
  4. Research Versatility: Partha’s diverse research experience, ranging from clinical research coordination to plant tissue culture and drug analysis, shows his adaptability and broad expertise in various domains of biological science.
  5. Professional Development: Participation in numerous seminars, workshops, and webinars, including poster presentations at international conferences, reflects his commitment to continuous learning and dissemination of knowledge.

Areas of Improvement

  1. Practical Application Focus: While Partha’s research is highly theoretical and advanced, greater emphasis on practical applications and translational research might further strengthen his candidacy. This could involve exploring more collaborative projects with industry or interdisciplinary teams to apply his findings in real-world scenarios.
  2. Leadership and Collaboration: Although Partha has demonstrated strong research capabilities, leadership roles in collaborative research projects or mentoring junior researchers could enhance his profile. Active involvement in large-scale, multi-disciplinary projects might also broaden his impact.
  3. Broader Impact: Expanding the outreach and societal impact of his research beyond the academic community could be beneficial. Engaging in public science communication, community outreach, or contributing to policy discussions on health and biotechnology could elevate his profile.

     Education

    Partha Sarathi Nial’s academic journey is marked by consistent excellence in the field of biological sciences. He earned his Ph.D. in Biological Science from the CSIR-Institute of Minerals and Materials Technology, focusing on the intricate mechanisms of B-Z DNA transition and its implications in various human diseases. Before his doctoral studies, he completed his B.Ed. in Biological Science from Andhra University and both his M.Sc. and B.Sc. in Biotechnology from Ravenshaw University and Utkal University, respectively, graduating with first-division honors.

     Research Experience

    Partha’s research expertise is deeply rooted in the molecular dynamics of DNA structures. His doctoral research explores the B-Z DNA transition, G-Quadruplex formation, and the impact of Rare Earth Elements on DNA conformations. He has also contributed to projects on gene regulation, therapeutic applications, and DNA nanostructure assembly. His M.Sc. dissertation focused on the micropropagation of Uraria picta, and he has gained hands-on experience in biochemical and bacteriological analysis of dairy products, clinical research on diarrhea, and drug quality evaluation.

     Research Interests

    Partha’s research interests lie at the intersection of molecular biology, nanotechnology, and structural biophysics. He is particularly fascinated by the conformational switching of DNA structures, such as B-Z DNA transitions and G-quadruplex formations, which have significant implications in gene function regulation and nanotechnological applications. His work aims to uncover the underlying mechanisms of these transitions and explore their potential in medical and therapeutic innovations.

     Awards and Achievements

    Partha’s academic and research endeavors have been recognized with several prestigious awards. He secured the Junior Research Fellowship (CSIR-NET JRF) with an impressive All India Rank of 100 in Life Sciences in 2018. Additionally, he was selected as a Clinical Research Coordinator by Consortium Clinical Research Pvt Ltd. and as an Executive in Business Development by Thyrocare Technologies Ltd., showcasing his versatile expertise in both research and industry.

     Publications

    Partha Sarathi Nial has contributed to several high-impact publications in reputable scientific journals. Here are some of his key works:

    1. Nial, P. S., Sathyaseelan, C., Bhanjadeo, M. M., Tulsiyan, K. D., Rathinavelan, T., & Subudhi, U. (2024). Praseodymium chloride-mediated B-to-Z DNA transition in pyrimidine-purine repeat sequences: Simulation and biophysical study. Journal of Molecular Liquids, 125173. Link. Cited by: 5 articles.
    2. Nial, P. S., & Subudhi, U. (2024). Zeta potential of Z-DNA: A new signature to study BZ transition in linear and branched DNA. International Journal of Biological Macromolecules, 266, 131238. Link. Cited by: 3 articles.
    3. Satapathy, S. N., Nial, P. S., Tulsiyan, K. D., & Subudhi, U. (2024). Light rare earth elements stabilize G-quadruplex structure in variants of human telomeric sequences. International Journal of Biological Macromolecules, 254, 127703. Link. Cited by: 4 articles.
    4. Monalisa, K., Behera, S., Pidika, S. P., Nial, P. S., & Naik, S. K. (2024). In vitro propagation and assessment of genetic fidelity of Blepharispermum subsessile DC.: An endangered medicinal plant of India. Vegetos, 1-10. Link. Cited by: 2 articles.
    5. Baral, B., Nial, P. S., & Subudhi, U. (2023). Enhanced enzymatic activity and conformational stability of catalase in presence of tetrahedral DNA nanostructures: A biophysical and kinetic study. International Journal of Biological Macromolecules, 242, 124677. Link. Cited by: 6 articles.
    6. Gourai, M., Nayak, A. K., Nial, P. S., Satpathy, B., Bhuyan, R., Singh, S. K., & Subudhi, U. (2023). Thermal plasma processing of Moringa oleifera biochars: Adsorbents for fluoride removal from water. RSC Advances, 13(7), 4340-4350. Link. Cited by: 7 articles.
    7. Bhanjadeo, M. M., Nial, P. S., Sathyaseelan, C., Singh, A. K., Dutta, J., Rathinavelan, T., & Subudhi, U. (2022). Biophysical interaction between lanthanum chloride and (CG) n or (GC) n repeats: A reversible B-to-Z DNA transition. International Journal of Biological Macromolecules, 216, 698-709. Link. Cited by: 9 articles

    Conclusion

    Partha Sarathi Nial is a highly deserving candidate for the Research for Best Researcher Award. His strong research background in DNA nanotechnology, coupled with significant publications and recognitions, makes him a standout candidate. To further enhance his profile, focusing on practical applications, taking on leadership roles in collaborative research, and broadening the societal impact of his work are recommended. Overall, his current achievements and potential for future contributions to science make him a suitable and strong contender for the award.