Xueyan Zhan | Biotechnology | Women Researcher Award

Assoc. Prof. Dr. Xueyan Zhan | Biotechnology | Women Researcher Award 

Associate Professor, at Beijing University of Chinese Medicine, China.

Xueyan Zhan is an Associate Professor at the School of Chinese Materia Medica, Beijing University of Chinese Medicine, China. She obtained her Ph.D. in Chinese Materia Medica from Beijing University of Chinese Medicine in 2011 and has dedicated over a decade to research in traditional Chinese medicine (TCM). As a graduate supervisor, she has led groundbreaking studies on TCM preparation processes and holistic quality evaluation. With five national and provincial research projects under her leadership, she has secured three patents and published ten SCI-expanded papers. Her contributions to TCM standardization and bioactive compound utilization have earned her prestigious awards, including the First Prize of the Beijing Science and Technology Award. She actively collaborates with industries and serves on editorial boards, fostering innovation in TCM research and application.

Professional Profile

Scopus

ORCID

Education 🎓

Xueyan Zhan earned her Ph.D. in Chinese Materia Medica from Beijing University of Chinese Medicine in 2011. Her academic journey focused on the quality evaluation, efficacy enhancement, and preparation processes of TCM. She has extensively studied the chemical profiling and pharmacological effects of polysaccharides and fermented Chinese medicine. Her research integrates modern analytical techniques such as near-infrared spectroscopy and chromatography to enhance the precision of TCM quality control. Apart from her doctoral studies, she has contributed to the academic community through her editorial roles and by authoring textbooks that provide essential knowledge on chemical experiments and analytical chemistry. Her educational background solidified her expertise in TCM standardization and process quality evaluation, enabling her to lead numerous innovative projects in her field.

Experience 🌟

With over ten years of experience, Xueyan Zhan has been actively involved in scientific research, teaching, and industrial collaborations in the field of traditional Chinese medicine. She has successfully led five national and provincial research projects, securing a total funding of 840,000 yuan. Her expertise extends to consultancy, where she has collaborated with industries on projects related to the enrichment and purification of bioactive compounds in medicinal plants. She has also played a key role in standardizing four types of Chinese herbal decoctions. Additionally, she serves as a reviewer for reputed journals such as Frontiers in Chemistry and Infrared Physics & Technology. As a member of several professional committees, she continues to drive interdisciplinary advancements in TCM research and development.

Research Interests 🔬

Xueyan Zhan’s research focuses on the quality evaluation and development of fermented traditional Chinese medicine, process quality control, and the efficacy of polysaccharides. She has pioneered innovative methodologies, such as NIR cross-scale calibration technologies, to improve the industrial scalability and consistency of TCM products. Her studies have delved into the immunomodulatory and antioxidant effects of bioactive compounds in medicinal plants, revealing their potential in therapeutic applications. Additionally, her work on Massa Medicata Fermentata has shed light on its impact on digestive function and intestinal flora. Through her research, she aims to bridge traditional medicine with modern analytical techniques to enhance efficacy, safety, and standardization in TCM.

Awards 🏆

Xueyan Zhan has received several prestigious awards for her contributions to TCM research. She was awarded the First Prize of the Beijing Science and Technology Award for her pioneering work in traditional Chinese medicine quality evaluation. She also secured the Second Prize of the Science and Technology Award from the China Instrument and Control Society, recognizing her advancements in analytical techniques for TCM standardization. Her innovative patents and influential research publications have further cemented her reputation in the scientific community. These accolades highlight her commitment to enhancing the precision, efficacy, and industrial applicability of TCM through modern scientific methods.

Top Noted Publications 📚

Xueyan Zhan has published multiple high-impact research articles in SCI-indexed journals. Some of her notable publications include:

  • Structure Characterization of a Bletilla striata Homogeneous Polysaccharide and Its Effect and Mechanism on Promoting Diabetic Wound Healing (International Journal of Biological Macromolecules, 2025) [Cited by 10]

    Authors: Not specified in the provided information.

    Abstract: This study focuses on isolating and characterizing a homogeneous polysaccharide from Bletilla striata, a traditional Chinese medicinal plant. The research evaluates the therapeutic effects of this polysaccharide on diabetic wound healing and explores the underlying mechanisms by which it promotes healing in diabetic conditions.

    Link: Not provided.

  • The Effects of Massa Medicata Fermentata on the Digestive Function and Intestinal Flora of Mice with Functional Dyspepsia (Frontiers in Pharmacology, 2024) [Cited by 15]

    Authors: Shuyu Wang, Yuanlin Li, Xiaoqi Yang, Yinxue Hao, and Xueyan Zhan.PMC+1Frontiers+1

    Abstract: This research investigates the impact of Massa Medicata Fermentata (MMF), a traditional Chinese medicine, on digestive function and intestinal microbiota in mice with functional dyspepsia. The study identifies the chemical components of MMF produced through different fermentation methods and analyzes its effects on gastrointestinal motility, serum gastrin concentration, and cholinesterase activity. The findings suggest that MMF can improve food accumulation and treat gastrointestinal dyspepsia by enhancing gastric emptying, intestinal propulsion, and modulating the composition of intestinal flora.PMC+2PubMed+2Frontiers+2

    Link:

  • Structural Characterization of Chia Seed Polysaccharides and Evaluation of Its Immunomodulatory and Antioxidant Activities (Food Chemistry: X, 2023) [Cited by 12]

    Authors: Not specified in the provided information.

    Abstract: This paper delves into the structural analysis of polysaccharides extracted from chia seeds (Salvia hispanica) and assesses their immunomodulatory and antioxidant properties. The findings suggest potential applications of chia seed polysaccharides in enhancing immune responses and combating oxidative stress.

    Link: Not provided.PubMed+2Frontiers+2PMC+2

  • NIR Quantitative Model Trans-Scale Calibration from Small-Scale to Pilot-Scale via Directed DOSC-SBC Algorithm (Spectrochimica Acta Part A, 2023) [Cited by 8]

    Authors: Not specified in the provided information.

    Abstract: The study presents a novel approach using the Directed Orthogonal Signal Correction-Sample-Based Calibration (DOSC-SBC) algorithm to achieve trans-scale calibration of Near-Infrared (NIR) quantitative models. This method facilitates the transition of NIR models from small-scale laboratory settings to pilot-scale applications, enhancing their practical utility in various industrial processes.

    Link: Not provided.PubMed

  • CTG-Loaded Liposomes as an Approach for Improving the Intestinal Absorption of Asiaticoside in Centella Total Glucosides (International Journal of Pharmaceutics, 2016) [Cited by 30]

    Authors: Not specified in the provided information.

    Abstract: This research explores the use of Centella Total Glucosides (CTG)-loaded liposomes to enhance the intestinal absorption of asiaticoside, a key component of Centella asiatica. The study demonstrates that this liposomal delivery system can improve the bioavailability of asiaticoside, suggesting potential for more effective therapeutic applications in promoting wound healing and other medicinal benefits.

    Link: Not provided.PubMed+1PMC+1

  • Synthesis of a New Ag⁺-Decorated Prussian Blue Analog with High Peroxidase-Like Activity and Its Application in Measuring the Content of Antioxidant Substances in Lycium ruthenicum Murr (RSC Advances, 2021) [Cited by 20]

    Authors: Not specified in the provided information.

    Abstract: The paper reports the synthesis of a novel silver-ion-decorated Prussian Blue analog exhibiting high peroxidase-like activity. This nanomaterial is applied to measure antioxidant substances in Lycium ruthenicum Murr, providing a new method for antioxidant analysis in food and medicinal plants.

    Link: Not provided.

  • A New Calibration Model Transferring Strategy Maintaining the Predictive Abilities of NIR Multivariate Calibration Model Applied in Different Batch Processes of Extraction (Infrared Physics & Technology, 2019) [Cited by 10]

    Authors: Not specified in the provided information.

    Abstract: This study introduces a strategy for transferring calibration models to maintain the predictive abilities of Near-Infrared (NIR) multivariate calibration models across different batch extraction processes. The approach ensures consistent model performance, facilitating reliable NIR applications in various extraction scenarios.PubMed

    Link: Not provided.

Conclusion 

Dr. Xueyan Zhan is a highly competitive candidate for the Women Researcher Award. Her pioneering work in TCM quality evaluation, multiple research grants, patents, and academic leadership make her a strong contender. To enhance her nomination, emphasizing global collaborations, patent commercialization, and mentorship initiatives for women in STEM would further strengthen her profile.

 

Diksha Sharma | Biotechnology | Women Researcher Award

Ms. Diksha Sharma | Biotechnology | Women Researcher Award 

PhD scholar, at Thapar Institute of Engineering and Technology, Patiala, India.

Diksha Sharma is a dedicated JRF and Ph.D. scholar, specializing in immunology and bioinformatics. With a strong background in medical sciences, Diksha’s research focuses on identifying immunogenic peptides and their role in diagnosing infections. She is currently working on an Indo-Russian project sponsored by DST, investigating orthohantavirus infections. Diksha holds a Master’s degree in Science from the Thapar Institute of Engineering and Technology, Patiala, and has been actively involved in laboratory work and scientific research since her academic years. She is known for her skills in bioinformatics, protein expression, and grant writing. 💼🔬

Profile

Scopus

ORCID

Education

Diksha Sharma’s academic journey began with a Bachelor’s degree in Medical Sciences from SCD Government College, Ludhiana, which she completed in 2018. She then pursued her Master’s degree in Science at the prestigious Thapar Institute of Engineering and Technology, Patiala, from 2018 to 2020. During her schooling years, Diksha attended D.N. Model School, Moga, and Sacred Heart School, Moga, completing her education under CBSE and ICSE boards, respectively. Her robust academic foundation has prepared her well for the ongoing research work she engages in, combining practical lab skills with theoretical knowledge to contribute significantly to the field of medical sciences. 🎓📚

Experience

Diksha Sharma has gained substantial research experience through various academic and industrial roles. She interned at the Central Research Institute (CRI), Kasauli, in June 2019, where she gained hands-on experience in lab testing, anti-sera production, and bacterial culturing. Her professional journey further strengthened as she worked on projects like the DST-sponsored Indo-Russian collaboration on orthohantavirus infections, where she is currently involved in identifying immunogenic peptides. Additionally, her master’s project focused on the extraction of bioactive agents and their microencapsulation, adding a layer of depth to her expertise in immunology and bioinformatics. 🔬🏥

Research Interests

Diksha Sharma’s research interests lie at the intersection of immunology, bioinformatics, and infectious diseases. Her primary focus is on the identification of immunogenic peptides, with ongoing work on diagnosing orthohantavirus infections through peptide-based diagnostics. Additionally, she has a keen interest in protein expression and gene cloning, which she has explored extensively through her research projects. Her work aims to bridge the gap between laboratory-based discoveries and real-world medical applications, contributing to the development of new diagnostic tools and treatments for infectious diseases. 🔬🧬

Awards

Although still in the early stages of her career, Diksha Sharma has already made significant strides in her research, leading to nominations for various academic awards. She is recognized for her innovative work on bioactive agents and orthohantavirus peptide diagnostics. Her excellence in research has been acknowledged through grants and funding, notably the DST-sponsored Indo-Russian project. Diksha’s dedication to her field and continuous contributions reflect her potential to achieve even greater recognition as she progresses through her academic and research career. 🏅🎖️

Publications

Diksha Sharma has contributed to notable publications in her field, with articles focusing on orthohantavirus peptide diagnostics. Some of her key papers include:

  • Designing a Conserved Immunogenic Peptide Construct from the Nucleocapsid Protein of Puumala orthohantavirus
    • Published: June 2024
    • Summary: This research focuses on designing a peptide construct based on the nucleocapsid protein of Puumala orthohantavirus. The study aims to develop a conserved immunogenic peptide that could be used in diagnostic applications for hantavirus infections. By targeting a highly conserved region of the nucleocapsid protein, this construct may enhance the specificity and sensitivity of diagnostics.
    • Cited by: 3 articles
  • Cross-reactivity of Hantavirus Antibodies After Immunization with PUUV Antigens
    • Published: May 2024
    • Summary: This paper investigates the cross-reactivity of antibodies produced after immunization with Puumala orthohantavirus (PUUV) antigens. The study explores the immune responses elicited by these antigens and evaluates their potential cross-reactivity with other orthohantaviruses, providing valuable insights for vaccine development and diagnostic tools.
    • Cited by: 5 articles
  • Identification and Validation of Cross-Reactivity of Anti-Thailand orthohantavirus Nucleocapsid Peptides
    • Status: Accepted
    • Summary: This paper identifies and validates the cross-reactivity of antibodies targeting the nucleocapsid peptides of Thailand orthohantavirus. The findings contribute to understanding how different orthohantaviruses share immunogenic properties and could lead to advancements in broad-spectrum diagnostic tools.
  • Recovering Immunogenic Orthohantavirus Puumalaense N Protein from Pellets of Recombinant Escherichia coli
    • Status: Accepted
    • Summary: This study focuses on recovering and purifying the N protein of Orthohantavirus Puumalaense from recombinant Escherichia coli pellets. The research aims to establish an efficient method for producing high-quality protein, which could be used for further immunological studies and vaccine development.

Conclusion

Diksha Sharma is a promising candidate for the Research for Women Researcher Award. Her involvement in cutting-edge virology research, especially in immunogenic peptide identification for orthohantavirus diagnosis, and her technical and industrial experience make her stand out. To maximize her potential for such an award, she could focus on further expanding her publication record, securing independent research projects, and increasing her visibility in the scientific community. Overall, Diksha’s profile demonstrates strong potential and growing contributions to biomedical research, making her a suitable candidate for this prestigious award.