Essa M. Saied | Molecular Biology | Research Excellence Award

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Assoc. Prof. Dr. Essa M. Saied | Molecular Biology | Research Excellence Award 

Associate Professor | Humboldt University of Berlin | Germany

Associate Prof. Dr. Essa M. Saied is a distinguished biochemist and bioorganic chemist whose work advances synthetic medicinal chemistry, lipid biochemistry, and small-molecule drug discovery. Holding research appointments at Humboldt University of Berlin and Suez Canal University, he has built an international reputation through 72 published documents, 2,232 citations from 1,538 citing sources, and an h-index of 31. His research integrates organic synthesis, lipid biochemistry, and computational design to identify small-molecule inhibitors of key sphingolipid-metabolizing enzymes. He employs high-throughput screening, enzymatic assays, molecular modeling, and structure–activity analysis to explore biochemical pathways relevant to cancer, inflammation, and metabolic disorders. His work also develops heterocyclic scaffolds, fluorescent probes, and biochemical tools that deepen understanding of lipid signaling and enzyme function. Through editorial service, peer review, and global collaboration, he continues to contribute significantly to chemical biology and therapeutic innovation.

Profiles: Scopus | ORCID| Google Scholar

Featured Publications

Live-Cell Identification of CERT Inhibitors via NanoBRET. Angewandte Chemie, Impact Factor 16.1.

Small-Molecule Ceramidase Inhibitors: Mechanism of Action. Angewandte Chemie, Impact Factor 16.8.

Stereoselective Synthesis of Novel Sphingoid Bases. International Journal of Molecular Sciences, Impact Factor 6.21.

Subunit Composition of Serine-Palmitoyltransferase. Proceedings of the National Academy of Sciences (PNAS), Impact Factor 11.2.

Resolving Sphingolipid Isomers Using Cryogenic IR Spectroscopy. Angewandte Chemie, Impact Factor 15.3.

RAJKUMAR MANICKAM | Molecular Biology | Molecular Biology Scientist Award

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Assist. Prof. Dr. RAJKUMAR MANICKAM | Molecular Biology | Molecular Biology Scientist Award 

Assistant Professor | Karpagam Academy of Higher Education | India

Assist. Prof. Dr. Manickam Rajkumar is an accomplished scientist recognized for his work in nanotechnology, molecular biology, and biomedical applications. His research spans biopolymer-based nanocomposites, green nanotechnology, drug delivery systems, and therapeutic strategies for neurodegenerative diseases, cancer, and microbial infections. With strong interdisciplinary training and extensive experience in in vitro, in vivo, and in silico methodologies, he contributes to advanced material synthesis, biomolecular characterization, behavioural neuroscience, and molecular diagnostics. His studies have identified nanocomposites with significant antioxidant capacity, modulation of toxic protein aggregation, and cognitive enhancement potential in disease models. His research interests include computational biology, biomedical coatings, metal oxide nanostructures, metabolic disorder therapeutics, and marine bioactive materials. He has produced impactful scientific contributions reflected in 325 citations, 232 citing documents, 27 publications, and an h-index of 11. His work has earned competitive fellowships and multiple best presentation awards at major scientific conferences, underscoring his influence as a growing researcher in biomedical innovation.

Profiles: Scopus | ORCID | Google Scholar
Featured Publications

Biosynthesis of cerium oxide nanoparticles. Biomedical Materials & Devices.

Review on green synthesis of nanoparticles. Biomedical Materials & Devices.

Biosynthesis of chitosan–TiO₂ nanoparticles. Inorganic Chemistry Communications.

CuO nanoparticles for colon cancer therapy. Journal of Cluster Science.

NanoMarine therapeutics for colon cancer. Frontiers in Genetics.

Eco-friendly synthesis of ZnO nanoparticles. Inorganic Chemistry Communications.

Georges Nemer | Molecular Biology | Editorial Board Member

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Prof. Georges Nemer | Molecular Biology | Editorial Board Member 

Professor | Hamad Bin Khalifa University | Qatar

Dr. Georges Nemer is a prominent molecular cardiology and biomedical research expert whose work spans cardiac development, congenital heart defects, transcriptional regulation, and translational molecular biology. His research has uncovered key mechanisms governing cardiogenesis, including defining the role of the T-box transcription factor Tbx5 in heart formation and disease, demonstrating how GATA-4 overexpression enhances cardiogenesis in embryonic stem cells, and revealing the cooperative regulation of myocardial gene expression by GATA-4 and GATA-6. Dr. Nemer has also contributed to clinical genetics through the identification of novel GATA4 mutations associated with Tetralogy of Fallot, supporting improved understanding of congenital heart malformations. Beyond cardiology, his scholarship extends to dermatological science, elucidating molecular pathways and clinical applications of retinoids, and to computational biochemistry through work on protein-ligand docking using AutoDock for targets such as BACE1. His interdisciplinary portfolio reflects a commitment to bridging basic science and clinical relevance, advancing knowledge across cardiac biology, human genetics, molecular therapeutics, and biomedical modeling.

Profile: Google Scholar

Featured Publications

Bruneau, B. G., Nemer, G., Schmitt, J. P., Charron, F., Robitaille, L., Caron, S., …
(2001). A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell, 106(6), 709–721.

Grépin, C., Nemer, G., & Nemer, M. (1997). Enhanced cardiogenesis in embryonic stem cells overexpressing the GATA-4 transcription factor. Development, 124(12), 2387–2395.

Charron, F., Paradis, P., Bronchain, O., Nemer, G., & Nemer, M. (1999). Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression. Molecular and Cellular Biology, 19(6), 4355–4365.

Khalil, S., Bardawil, T., Stephan, C., Darwiche, N., Abbas, O., Kibbi, A. G., …
(2017). Retinoids: A journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effects. Journal of Dermatological Treatment, 28(8), 684–696.

Nemer, G., Fadlalah, F., Usta, J., Nemer, M., Dbaibo, G., Obeid, M., & Bitar, F. (2006). A novel mutation in the GATA4 gene in patients with Tetralogy of Fallot. Human Mutation, 27(3), 293–294.

El-Hachem, N., Haibe-Kains, B., Khalil, A., Kobeissy, F. H., & Nemer, G. (Year unavailable). AutoDock and AutoDockTools for protein-ligand docking: Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a case study. Neuroproteomics: Methods and Protocols, 391–403.

ZHANG TING | Molecular Biology | Young Scientist Award

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Ms. ZHANG TING | Molecular Biology | Young Scientist Award 

Teacher | China Kashi University | China

Dr. Zhang Ting is a distinguished Chinese biologist specializing in biological resources, nutritional biochemistry, and translational medicine. He earned his Bachelor of Nutrition, Master’s in Nutritional Studies, and Doctor of Biology from Hoseo University, South Korea, focusing on integrative nutrition, functional foods, and systems biology. His doctoral research explored neuropharmacological mechanisms in Alzheimer’s disease, stroke, diabetes, and obesity, combining molecular assays, rodent behavioral studies, and herbal medicine bioactivity. With over a decade of laboratory experience, Zhang has worked at Hoseo University and YEJUN Institute of Biological Sciences, leading experiments on metabolic regulation, neuroprotection, and chronic disease models while mentoring junior scientists and overseeing laboratory safety. His research interests include gut-brain axis modulation, herbal and fermented food interventions, metabolic disorders, and diet-based cognitive enhancement. Zhang bridges traditional medicinal knowledge with modern translational medicine, aiming to develop innovative strategies for chronic disease mitigation. His work has been widely cited and recognized internationally, reflecting his contributions to nutritional biochemistry, neuropharmacology, and functional food research, positioning him as a rising leader in integrative biomedical science.

Profile: ORCID

Featured Publications

Zhang, T., & Park, S. (n.d.). Network pharmacology-guided discovery of traditional Chinese medicine extracts for Alzheimer’s disease: Targeting neuroinflammation and gut-brain axis dysfunction. Int J Mol Sci, 26(17), 8545. Cited by 12.

Zhang, T., & Park, S. (n.d.). Energy intake-dependent genetic associations with obesity risk: BDNF Val66Met polymorphism and interactions with dietary bioactive compounds. Antioxidants, 14(2), 170.

Zhang, T., Yue, Y., Li, C., et al. (n.d.). Vagus nerve suppression in ischemic stroke by carotid artery occlusion: Implications for metabolic regulation, cognitive function, and gut microbiome in a gerbil model. Int J Mol Sci, 25, 7831.

Zhang, T., Li, C., Yue, Y., et al. (n.d.). Fermented red pepper paste (Kochujang) modulates glucose metabolism and gut microbiota in parasympathetic suppression: Network pharmacology and in vivo study. Food Biosci, 104531.

Zhang, T., Yue, Y., Jeong, S. J., et al. (n.d.). Improvement of estrogen deficiency symptoms by long-term fermented soybeans (Doenjang) rich in Bacillus species through modulating gut microbiota in estrogen-deficient rats. Foods, 12(6), 1143.

Shangze Li | Molecular Biology | Best Researcher Award

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Assoc. Prof. Dr. Shangze Li | Molecular Biology | Best Researcher Award 

Assistant to the Dean | Chongqing University | China

Dr. Shangze Li (Ph.D., Associate Professor, Ph.D. Supervisor) is a distinguished researcher in the fields of antiviral innate immune signaling, inflammatory responses, and tumor biology. He is based at the School of Medicine, Chongqing University, where he leads a research group and supervises doctoral students. His work integrates advanced genetic engineering technologies such as gene knockout, knock-in approaches, and disease models to investigate the molecular basis of immune regulation and cancer development. Dr. Li has published extensively in leading international journals including Nature Communications, Cell Death and Differentiation, Cancer Research, Oncogene, and Cancer Letters, with several contributions featured in Nature Index journals. His studies have been widely cited, reflecting both scientific impact and relevance to the global biomedical community. In addition to research, he is actively involved in teaching, mentoring, editorial service, and academic leadership, contributing to the advancement of both education and medical research.

Professional Profile

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ORCID

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Education 

Dr. Li completed his doctoral degree in Cell Biology at Wuhan University, where he focused on the molecular mechanisms that link immune regulation to tumorigenesis. Prior to his doctoral training, he pursued two undergraduate degrees, one in Bioengineering from the Chengdu University of Technology and another in Business Administration from the University of Electronic Science and Technology of China. This unique combination of scientific and managerial education provided him with both technical expertise and leadership skills. After completing his doctorate, Dr. Li undertook postdoctoral training at the Feinberg School of Medicine, Northwestern University, where he worked on projects exploring molecular oncology, innate immunity, and translational approaches in cancer research. His diverse academic background, spanning engineering, business, molecular biology, and medical research, has prepared him to integrate interdisciplinary knowledge in his career. This foundation continues to guide his role as a scientist, supervisor, and contributor to medical and biological sciences.

Experience 

Dr. Li began his professional research career at the Feinberg School of Medicine, Northwestern University, where he served as a postdoctoral researcher in molecular oncology and immune regulation. Following this period of international training, he returned to China and accepted an appointment at Zhongnan Hospital of Wuhan University and the College of Life Sciences, where he contributed to teaching and research in biomedical sciences. He later joined the School of Medicine at Chongqing University as a faculty member, where he was subsequently promoted to Associate Professor and Ph.D. Supervisor. In this role, he leads a laboratory focused on investigating immune signaling and cancer development. In addition to his research and teaching, Dr. Li has taken on administrative responsibilities, serving as Assistant to the Dean and Deputy Director of Shared Core Facilities for Medical Research. His experience reflects a career that balances leadership, education, and internationally recognized scientific research.

Research Interests 

Dr. Li’s research centers on the molecular mechanisms of innate immune signaling, inflammation, and tumor biology. His work explores how signaling pathways regulate immune homeostasis and contribute to tumor initiation and progression. He employs genetically modified cell lines, CRISPR-based technologies, and animal models to examine the functional roles of key genes in these processes. His studies often focus on ubiquitination and deubiquitination pathways, NF-κB signaling, and the crosstalk between cellular metabolism and cell death. This approach provides critical insights into how molecular dysregulation drives oncogenesis and resistance to therapy. His research also emphasizes translational applications, identifying potential biomarkers and therapeutic strategies that may guide novel approaches in cancer treatment and immune-related diseases. By integrating molecular biology, immunology, and cancer research, Dr. Li contributes to advancing both fundamental scientific knowledge and practical innovations for improving health outcomes.

Awards 

Dr. Li’s research achievements have been recognized through broad citation and publication in top international journals. His scholarly contributions have been acknowledged in Nature Communications, Molecular Cancer, Cancer Research, and other leading journals, with some articles featured as cover stories in Nature Index publications. His body of work has earned substantial recognition in the scientific community, reflected in a strong citation record and consistent invitations to review for leading journals. He has also served as Guest Editor for Vaccines and as a reviewer for the National Natural Science Foundation of China, underscoring his role as a trusted scientific evaluator. Beyond research output, Dr. Li has contributed actively to professional organizations, including serving as a council member of the Chongqing Association of Young Scientists and participating in national academic initiatives. His record demonstrates recognition for both scholarly impact and professional service, positioning him as a strong candidate for scientific honors.

Top Noted Publications 

Dr. Li has authored more than forty peer-reviewed publications, including a substantial number as first or corresponding author. His research has appeared in high-impact journals such as Nature Communications, Molecular Cancer, Oncogene, Cancer Research, and Cancer Letters. Selected publications include Ubiquitin-Specific Protease 1 Promotes Bladder Cancer Progression in Cells, CLK2 mediates NF-κB regulation in Nature Communications, Crosstalk between metabolism and cell death in tumorigenesis in Molecular Cancer, USP14 promotes colorectal cancer progression in Cell Death & Disease, and MAPK signaling and drug resistance in prostate cancer in Cancer Research. These publications reflect his long-term focus on the molecular basis of immune regulation and cancer biology. His findings have been widely cited and have advanced understanding of tumorigenesis, therapeutic resistance, and immunoregulation. Collectively, his research portfolio highlights his contributions to both fundamental science and translational medicine, strengthening his standing as an influential scholar in the field of biomedical research.

Title: Ubiquitin-Specific Protease 1 Promotes Bladder Cancer Progression
Journal: Cells
Year: 2024
Cited by: 15+

Title: CLK2 mediates IkappaBalpha-independent NF-κB regulation
Journal: Nature Communications
Year: 2024
Cited by: 30+

Title: Crosstalk between metabolism and cell death in tumorigenesis
Journal:  Molecular Cancer
Year: 2024
Cited by: 40+

Title: USP14 promotes colorectal cancer progression
Journal: Cell Death & Disease
Year: 2023
Cited by: 25+

Title: Activation of MAPK by CXCR7 causes drug resistance
Journal: Cancer Research
Year: 2019
Cited by: 200+

Conclusion

Dr. Shangze Li is a highly suitable candidate for the Best Researcher Award. His outstanding research achievements, strong academic influence, and balanced contributions to teaching, mentorship, and professional service highlight his excellence as a scholar. With continued focus on international collaboration, high-impact publications, and global leadership roles, he is exceptionally well-positioned to be recognized with this award.

Baran SEVEN | Molecular Biology | Best Paper Award

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Dr. Baran Seven | Molecular Biology | Best Paper Award

Doctorate | TST Fittings and Medical Devices Industry and Trade | Turkey

Dr. Baran Seven is a committed biologist whose academic journey reflects a deep focus on toxicology, molecular biology, and environmental sciences. He earned his undergraduate, master’s, and doctoral degrees in Biology from Giresun University. His research has primarily involved investigating the toxicological effects of various chemical compounds on in vivo models, particularly Swiss albino mice. Throughout his academic progression, he has actively participated in multiple national and international scientific projects, often examining the protective effects of natural plant extracts against induced toxicities. Dr. Seven has published extensively in peer-reviewed journals and has presented his findings at numerous scientific conferences. His work demonstrates an interdisciplinary approach, blending physiological, genetic, and biochemical methods to assess and mitigate toxicity. With a strong background in both laboratory research and academic collaboration, Dr. Seven continues to contribute significantly to the fields of environmental toxicology and biomedical sciences.

Professional Profile

Scopus

Education

Dr. Baran Seven completed his entire academic training in Biology at Giresun University, Turkey. He obtained his Bachelor’s degree in 2013, followed by a Master’s degree in 2015 under the supervision of Associate Professor Kültiğin Çavuşoğlu and Professor Kürşad Yapar. His master’s thesis, titled “Albino farelerde paraben tarafından teşvik edilen toksisiteye karşı ısırgan otu özütünün koruyucu rolünün araştırılması,” focused on evaluating the protective effects of nettle extract against paraben-induced toxicity in albino mice. Continuing his studies at the same institution, he earned his Ph.D. in 2022 with a dissertation entitled “Swiss albino farelerde sipermetrin toksisitesinin araştırılması: Fizyolojik, genetik ve biyokimyasal yaklaşım,” supervised by Professor Kültiğin Çavuşoğlu. His doctoral research took a multidisciplinary approach, analyzing cypermethrin-induced toxicity through physiological, biochemical, and genetic methodologies. This comprehensive education has provided Dr. Seven with a solid foundation in experimental biology and toxicology.

Experience

Dr. Baran Seven has contributed to several scientific projects, primarily in the capacity of assistant researcher. His experience includes laboratory-based toxicological studies involving Allium cepa root tip cells and Swiss albino mice. He played a central role in experiments examining the effects of ultraviolet radiation, parabens, heavy metals such as lead, and chemical agents like ammonium sulfate on genetic and physiological parameters. His involvement extended to analyzing the protective effects of natural substances, including Urtica dioica (nettle), Nigella sativa (black seed), carotene, and grape seed extract. Dr. Seven has also explored the antimicrobial and insecticidal properties of Pseudomonas species isolated from wastewater, contributing to the field of microbial biotechnology. He has consistently presented his findings at international and national congresses and has co-authored multiple scientific publications. His expertise spans DNA damage analysis, chromosomal aberration testing, and biochemical assessments, positioning him as a versatile and experienced researcher in biological sciences.

Research Interest

Dr. Baran Seven’s research interests focus on the fields of toxicology, genotoxicity, antioxidant mechanisms, and environmental biology. His primary research aims to evaluate the adverse effects of toxic chemicals such as cypermethrin, parabens, lead nitrate, bisphenol A, and various pesticides on biological systems. He employs animal models, particularly Swiss albino mice, and plant models like Allium cepa, to assess toxicity at genetic, biochemical, and physiological levels. A central theme in his work is the protective potential of natural compounds, including plant extracts and microbial isolates, against chemical-induced genotoxicity and oxidative stress. His methodologies include the use of comet assays, chromosomal aberration analysis, and biochemical marker evaluation to measure DNA damage and cellular response. Dr. Seven’s interdisciplinary approach allows him to contribute meaningfully to both the scientific understanding of toxic substances and the development of potential mitigation strategies using eco-friendly and natural agents.

Awards and Recognition

Although specific individual awards are not explicitly listed, Dr. Baran Seven’s academic profile demonstrates a strong pattern of recognition through conference participation and publication. He has been a consistent contributor to various prestigious scientific meetings, including the International Black Sea Congress on Environmental Sciences, Ecology Symposiums, and the International Anatolian Scientific Research Congress. His role in these conferences has often included presenting full-text research papers and co-authoring collaborative studies, signaling professional acknowledgment from the academic community. Additionally, his ongoing contributions to peer-reviewed journals and collaborative research projects underscore his growing influence in the field. The publication of his doctoral research in high-impact journals, such as Scientific Reports, is a testament to the quality and significance of his work. Dr. Seven’s consistent engagement with both national and international scientific forums indicates a promising academic trajectory and potential for future formal recognitions.

Top Noted Publications

Dr. Baran Seven has authored and co-authored several peer-reviewed articles in national and international journals, emphasizing toxicology, genotoxicity, and microbiology. Key publications include:

Title: Investigation of cypermethrin toxicity in Swiss albino mice with physiological, genetic and biochemical approaches
 Year: 2022
Cited by: 5 articles

Title: Effects of feeding genetically modified (GM) maize on oxidative stress parameters in New Zealand rabbit
 Year: 2018

Title: Insecticidal and Antimicrobial Effects of Pseudomonas Species Isolated From Waste Water
Year: 2022.

Title: Albino Farelerde Paraben Tarafından Oluşturulan Genotoksisitenin Araştırılması: Isırgan Otu Özütünün Koruyucu Rolü
Year: 2017

Conclusion

Dr. Baran Seven is a strong and suitable candidate for the Best Paper Award, especially for his Scientific Reports publication which reflects scientific rigor, interdisciplinary methodology, and public health relevance. His research outputs contribute significantly to the understanding of environmental toxicology and the protective role of natural compounds. With ongoing efforts toward high-impact dissemination and broader scientific visibility, Dr. Seven is poised to make continued valuable contributions to the field.

Guoyin Liu | Molecular Biology | Best Researcher Award

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Assoc. Prof. Dr. Guoyin Liu | Molecular Biology | Best Researcher Award 

Attending physician and associate professor, at Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210093, China.

Dr. Guoyin Liu is an accomplished attending physician and associate professor at Jinling Hospital, Nanjing University, renowned for his expertise in orthopedics, inflammatory signaling, and regenerative medicine. Holding a PhD from Nanjing Medical University, he specializes in endoplasmic reticulum (ER) molecular chaperones such as GRP78/Bip and their role in critical orthopedic conditions including rheumatoid arthritis, osteoarthritis, chronic wounds, and periprosthetic osteolysis. Beyond molecular research, he pioneers innovative treatments like extracorporeal shock wave therapy, needle-knife therapy, and restorative laminoplasty techniques for spinal reconstruction. His translational research bridges basic science with clinical applications, contributing to novel interventions for musculoskeletal disorders. With an impressive portfolio of high-impact publications, key research grants, patents, and editorial board memberships, Dr. Liu exemplifies a commitment to advancing orthopedic science and patient care. His innovative contributions continue to shape the future of orthopedic diagnostics and treatments, fostering breakthroughs in bone regeneration and inflammatory disease management.

Professional Profile

Scopus

ORCID

🎓 Education 

Dr. Liu completed his PhD at Nanjing Medical University, focusing on the molecular mechanisms underlying inflammatory bone loss and tissue degeneration. His academic foundation integrates basic medical sciences, clinical orthopedics, and bioengineering approaches, enabling him to investigate complex orthopedic diseases at the cellular and molecular levels. During his training, he mastered advanced experimental techniques, including finite element biomechanical analysis, tissue engineering methodologies, and translational clinical trials. Dr. Liu expanded his academic horizon through specialized workshops in regenerative medicine, musculoskeletal biomechanics, and immunomodulation therapies. His education laid the groundwork for his pioneering research on GRP78/Bip signaling pathways in chronic musculoskeletal diseases. By blending clinical insights with experimental rigor, he has become a leading voice in developing innovative therapies for orthopedic patients. His educational journey reflects a seamless integration of theory and practice, empowering him to address both clinical challenges and fundamental biomedical questions with cutting-edge research approaches.

💼 Experience 

With over 15 years of combined clinical and research experience, Dr. Guoyin Liu has established himself as a leading expert in orthopedic surgery, translational research, and regenerative medicine. As an Attending Physician and Associate Professor at Jinling Hospital, he manages complex cases such as spinal deformities, chronic joint diseases, and osteolytic conditions. His academic tenure includes supervising multidisciplinary research projects funded by National Natural Science Foundation of China and provincial grants focusing on inflammatory pathways and bone regeneration. He has innovated surgical techniques like restorative laminoplasty with miniplate fixation, which has improved postoperative spinal stability and patient recovery outcomes. His extensive clinical experience is complemented by editorial board appointments in reputed international journals, reflecting his scientific leadership. Dr. Liu’s dual role as a clinician and researcher enables him to directly translate benchside discoveries into bedside applications, ensuring tangible benefits for patients suffering from chronic orthopedic disorders.

🔬 Research Interests 

Dr. Liu’s research is centered on cellular stress responses and inflammatory pathways in orthopedic diseases, with a special focus on endoplasmic reticulum molecular chaperones (GRP78/Bip) and their dual intracellular and extracellular roles. He investigates how particle-induced osteolysis, rheumatoid arthritis, and intervertebral disc degeneration are driven by inflammatory cascades, aiming to develop targeted molecular therapies. Another significant area of his research explores chemical chaperones like 4-Phenylbutyrate, which mitigate ER stress and improve bone regeneration. Dr. Liu also advances biomechanical engineering solutions, analyzing finite element models to improve spinal fixation techniques. Additionally, he integrates shockwave therapy, corticosteroid injections, and minimally invasive interventions for managing chronic orthopedic pain. His translational approach bridges basic science, bioengineering, and clinical orthopedics, leading to innovative strategies that reduce surgical complications and improve musculoskeletal repair. Through his research, Dr. Liu aims to redefine the diagnosis, prevention, and treatment of bone and joint diseases in aging populations.

🏆 Awards & Honors 

Dr. Liu has received numerous academic and clinical recognitions for his groundbreaking work in orthopedics. He was honored with the Third Prize for Military Science & Technology Progress for elucidating the TIM3 signaling pathway in osteoarthritis during military training-related injuries. Additionally, he received the Third Award for Nanjing Science & Technology Progress for identifying the role of recombinant BMP-1 in periprosthetic osteolysis. His work has been consistently supported by prestigious national grants, including multiple NSFC-funded projects totaling over ¥2 million, demonstrating the significance and impact of his research. Beyond awards, his appointment to editorial boards of leading orthopedic and bioengineering journals highlights his global recognition in the field. Dr. Liu’s innovative surgical methods, such as restorative laminoplasty with H-shaped miniplates, have been acknowledged as transformative in spinal reconstruction. These accolades collectively recognize his outstanding contribution to orthopedic research, surgical innovation, and patient care.

📚 Top Noted Publications 

Dr. Liu’s publications span orthopedic biomechanics, inflammatory pathways, and regenerative medicine, widely cited in the global research community. Key works include:

🛠️ Biomechanical Stability of Miniplates in Restorative Laminoplasty

Title: Comparative Biomechanical Stability of the Fixation of Different Miniplates in Restorative Laminoplasty after Laminectomy: A Finite Element Study
Authors: Guoyin Liu, Weiqian Huang, Nannan Leng, Peng He, Xin Li, Muliang Lin, Zhonghua Lian, Yong Wang, Jianmin Chen, Weihua Cai
Journal: Bioengineering (Basel)
Year / Volume / Issue: 2024; 11(5):519
DOI: 10.3390/bioengineering11050519 PubMed+15MDPI+15ResearchGate+15
Highlights: Used a finite element model (L2–L4) to compare H‑shaped, L‑shaped, and two‑hole miniplates. The H‑shaped design showed superior stability, especially in axial rotation and flexion/extension PubMedMDPI.

Biomechanical Reconstruction of the Posterior Complex in Laminoplasty

Title: Biomechanical evaluation of reconstruction of the posterior complex in restorative laminoplasty with miniplates
Authors: Jianmin Chen, Guoyin Liu, Tianyi Bao, Yuansheng Xu, Hu Luo, Yu Wu, Dawei Cai, Feng Qin, Jianning Zhao
Journal: BMC Musculoskeletal Disorders
Year / Volume / Article: 2023; 24(1):298
DOI: 10.1186/s12891-023-06380-3 PubMedOUCI
Highlights: Cadaveric 3D-printed L4 models under static/dynamic loading. H‑shaped miniplates outperformed L‑shaped and two-hole systems, preventing lamina collapse or plate breakage PubMedResearchGate.

Macrophage Apoptosis Pathways in Periprosthetic Osteolysis

Title: Apoptotic pathways of macrophages within osteolytic interface membrane in periprosthetic osteolysis
Journal: APMIS
Year: 2017
Details: Demonstrates that wear particles at implant interfaces accelerate macrophage apoptosis via ER-stress and mitochondrial dysfunction, which exacerbates osteolysis PubMedPhysiology Journals.

Endoplasmic Reticulum Stress and Osteolysis

Title: Endoplasmic reticulum stress-mediated inflammatory signaling pathways within the osteolytic periosteum and interface membrane in particle-induced osteolysis
Authors: Guoyin Liu, Naicheng Liu, Yuansheng Xu, Yunfan Ti, Jiangning Chen, Jianmin Chen, Junfeng Zhang, Jianning Zhao
Journal: Cell and Tissue Research
Year / Issue / Pages: 2016 Feb; 363(2):427–447
DOI: 10.1007/s00441-015-2205-9 PubMedSpringerLink
Highlights: Particle debris induces ER stress in macrophages, triggering IRE1α, GRP78/BiP, NF‑κB pathways, elevating pro-inflammatory cytokines (TNF‑α, IL‑1β, IL‑6). 4‑PBA effectively reduced ER-stress and osteolysis in murine models .

Conclusion

Dr. Guoyin Liu’s outstanding contributions to orthopedic research, innovative therapies, and patented medical devices make him a highly suitable candidate for the Best Researcher Award. His work bridges basic molecular research with clinical applications, significantly improving diagnosis, treatment, and rehabilitation of complex musculoskeletal disorders.