Heng Zhang | Molecular Biology | Best Researcher Award

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Dr. Heng Zhang | Molecular Biology | Best Researcher Award 

Lecturer | Nankai University | China

Dr. Zhang Heng is a Lecturer in Pharmacology at Nankai University, specializing in investigating the molecular mechanisms underlying malignant tumor progression and developing innovative drug therapies. He earned his B.S., M.S., and Ph.D. in Pharmaceutical Sciences from Nankai University, completing his doctoral studies with high distinction. Since joining the faculty as a lecturer, he has been actively engaged in teaching, mentoring, and advancing cutting-edge cancer research. Dr. Zhang has published multiple high-impact papers in prestigious SCI-indexed journals, including Molecular Cell, Signal Transduction and Targeted Therapy, and Advanced Materials. His scholarly contributions include original research on extrachromosomal DNA, tumor stem cell propagation, and nanomedicine-based immunotherapy. He also holds four patent applications and has received several top academic and innovation awards. Through his research and academic leadership, Dr. Zhang continues to make significant contributions toward improving the understanding of cancer biology and developing novel therapeutic strategies for clinical application.

Professional Profile

ORCID

Education

Dr. Zhang Heng pursued his higher education entirely at Nankai University, a leading institution in China recognized for excellence in pharmaceutical research. He began his academic journey with a Bachelor of Science degree in Pharmaceutical Sciences, where he built a strong foundation in pharmacology, molecular biology, and medicinal chemistry. Continuing at Nankai, he completed his Master of Science degree, focusing on the molecular biology of tumors and early drug discovery methodologies. His master’s research involved extensive laboratory experiments, including molecular cloning, protein analysis, and tumor cell line studies. Dr. Zhang then earned his Ph.D. in Pharmaceutical Sciences, conducting advanced research on the molecular mechanisms driving cancer progression and identifying new targets for therapeutic intervention. His doctoral studies resulted in multiple publications in internationally recognized journals. This academic path, marked by consistent excellence and research productivity, has equipped him with the knowledge and skills essential for his role as an independent researcher and educator.

Experience

Following the completion of his doctoral studies, Dr. Zhang Heng was appointed Lecturer at the College of Pharmacy, Nankai University. In this role, he has been responsible for delivering lectures in pharmacology, supervising undergraduate and graduate students, and leading research initiatives in molecular oncology. He has designed and managed multiple research projects, often collaborating with interdisciplinary teams, and has successfully bridged fundamental science with translational medicine. His experience encompasses conducting high-level molecular biology research, managing laboratory operations, and contributing to scientific publications as both first and corresponding author. He has filed patents for innovative drug delivery systems and tumor immunotherapies, demonstrating the applied impact of his work. Beyond laboratory research, Dr. Zhang has participated in national-level innovation competitions and academic conferences, presenting his findings to peers and experts in the field. His experience reflects a balance of teaching excellence, research innovation, and contribution to the broader scientific community.

Research Interest

Dr. Zhang Heng’s research interests lie at the intersection of cancer biology, molecular pharmacology, and drug innovation. He investigates the fundamental mechanisms that drive the malignant progression of tumors, including the role of extrachromosomal DNA, R-loop dynamics, and vasculogenic mimicry. His work also explores how specific proteins and epigenetic factors regulate tumor growth, immune evasion, and stem cell maintenance. In addition to basic research, Dr. Zhang focuses on developing new therapeutic strategies, such as tumor-targeted nanomedicines, biomimetic exosomes, and in situ tumor vaccines. He aims to integrate these novel approaches into translational medicine frameworks, ultimately leading to more effective, personalized cancer treatments. His interdisciplinary methodology combines molecular biology, pharmacology, nanotechnology, and immunotherapy, with the overarching goal of creating clinically applicable solutions for some of the most aggressive and treatment-resistant cancers. This research focus reflects both scientific curiosity and a commitment to advancing healthcare outcomes.

Award

Dr. Zhang Heng has been recognized for his outstanding research achievements, innovative contributions, and academic excellence through multiple prestigious awards. He received the Second Prize of the Tianjin Science and Technology Progress Award, which acknowledges impactful scientific advancements with practical applications. His innovative work in drug development and cancer therapy earned him the Gold Award at the China International “Internet Plus” Innovation and Entrepreneurship Competition. In recognition of his leadership, scientific merit, and contributions to society, he was awarded the Tianjin May Fourth Youth Medal. While a student, Dr. Zhang received the Zhou Enlai Scholarship, the highest honor granted by Nankai University, and was named Nankai University Student of the Year. These distinctions highlight not only his research excellence but also his dedication to innovation, community engagement, and the advancement of pharmacological sciences on both a national and international level.

Top Noted Publication

Dr. Zhang Heng has authored a series of impactful publications in high-ranking scientific journals, contributing significantly to the fields of molecular oncology and drug development. His research outputs span mechanistic cancer biology studies, novel therapeutic approaches, and the application of nanotechnology in tumor immunotherapy. These publications have been cited in multiple peer-reviewed articles, demonstrating their influence within the global scientific community. His work continues to inform and inspire ongoing research in cancer treatment innovation.

Publications list (single-line prompt):

Title: Extrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1–Lig3–PARylation complex
Journal: Molecular Cell
Year: 2025

Title: MTA2 triggered R-loop trans-regulates BDH1-mediated β-hydroxybutyrylation and potentiates propagation of hepatocellular carcinoma stem cells
Journal: Signal Transduction and Targeted Therapy
Year: 2021

Title: Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis
Journal: Advanced Materials
Year: 2022

Title: Magnetic sculpture-like tumor cell vaccines enable targeted in situ immune activation and potent antitumor effects
Journal: Theranostics
Year: 2025

Title: Vitamin D binding protein (VDBP) hijacks Twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma
Journal: Theranostics
Year: 2024

Conclusion

Dr. Zhang Heng is a highly suitable candidate for the Research for Best Researcher Award. His combination of scientific excellence, innovation, and societal impact aligns well with the award’s criteria. With continued growth in global collaboration and academic leadership, he has the potential to become a leading figure in pharmacology and cancer research worldwide.

 

King-cheong LAM | Molecular Biology | Best Researcher Award

Published on by Molecular Biologist

Dr. King-cheong LAM | Molecular Biology | Best Researcher Award

Senior Lecturer, at The School of Professional Education and Executive Development (SPEED), The Hong Kong Polytechnic University, Hong Kong.

Dr. LAM King-cheong Antony is a seasoned academic currently serving as a Senior Lecturer in the Division of Science, Engineering and Health Studies at the College of Professional and Continuing Education (CPCE), The Hong Kong Polytechnic University. With a rich interdisciplinary background in physics and engineering education, Dr. Lam has consistently contributed to innovative teaching methods and research initiatives. His career journey from a secondary school teacher to a respected university lecturer is marked by dedication to student development, academic leadership, and community outreach. 📘 His roles as Programme Leader and Co-Investigator in prestigious funded projects reflect his commitment to applied research and educational advancement. Through his work in nanotechnology, sustainable energy, and smart sensor systems, Dr. Lam exemplifies a professional devoted to shaping the future of science education and technology for sustainable urban living. 🌱

Professional Profile

Scopus

ORCID

🎓 Education

Dr. Antony Lam’s academic path is built on a solid foundation in science and education. 🎓 He earned his Doctor of Philosophy from The Hong Kong Polytechnic University in 2017, where he focused on gas sensing materials using graphene-based composites. Prior to that, he completed his Master of Philosophy (2008) and Bachelor of Science in Physics (2005) at The University of Hong Kong, establishing his grounding in physical sciences. Recognizing the importance of pedagogy in science, he also pursued a Postgraduate Diploma in Education from The University of Hong Kong in 2010, equipping himself with the skills to bridge research and teaching. This rare blend of scientific rigor and educational expertise empowers him to mentor students and lead cross-disciplinary research with confidence. 🧠 His training has laid the foundation for a career devoted to both scientific discovery and academic development.

💼 Experience

Dr. Lam’s professional career spans across secondary and tertiary education sectors. 🏫 From 2007 to 2012, he began his journey as a science teacher at Heung To Secondary School (TKO), where he nurtured young minds with enthusiasm for physics. In 2018, he transitioned to higher education as a Lecturer at CPCE, The Hong Kong Polytechnic University, and was promoted to Senior Lecturer in 2024. Over the years, Dr. Lam has taken on several key academic leadership roles, including Programme Leader for Associate in Engineering and Higher Diploma in Aircraft Services Engineering, and Assistant Programme Leader for the BEng (Hons) in Mechanical Engineering. 💼 These positions not only reflect his pedagogical expertise but also his capability in curriculum innovation and academic governance. Dr. Lam’s dedication to bridging practical engineering with academic training is central to his career mission of advancing applied science education. ⚙️

🔬 Research Interests

Dr. Lam’s research interests lie at the intersection of nanotechnology, green energy, sustainable materials, and smart sensing systems. 🌍 His work explores the fabrication of advanced materials such as tin-based perovskites, graphene composites, and aluminum-ion batteries to enhance energy efficiency and sensor capabilities. A significant part of his research addresses real-world sustainability challenges—ranging from developing natural fiber/concrete composites for eco-friendly buildings to ionic-liquid-based gas sensors for smart cities. 🏙️ He is also actively investigating thermal and mechanical properties of biomaterials, including mycelium-based composites for biomedical applications. His interdisciplinary approach combines physics, chemistry, and engineering to produce applicable technologies for energy and healthcare sectors. Through multiple funded projects and international conferences, Dr. Lam has established himself as a researcher committed to translational science for societal impact. 🌱

🏅 Awards

Dr. Lam’s research excellence has earned him both institutional recognition and competitive external grants. 🏆 In 2023, he received the KML Third Prize (HK$200,000) from the Koo Meng Li and Koo Mi Wen Na Charitable Foundation Limited for his project on natural fiber/concrete composites for sustainable buildings. He has been a Principal Investigator and Co-Investigator in numerous high-impact projects, including a nearly HK$1 million RGC-funded project on mycelium-based insoles for diabetic care. 💰 These awards and grants highlight his innovative work in sustainable technology and material science. Dr. Lam’s recognition not only reflects his technical acumen but also his leadership in building collaborative, real-world solutions. His consistent involvement in cutting-edge research underscores his role as a forward-thinking academic in science and engineering education. 🧪

📚 Top Noted Publications

Dr. Lam has contributed to a number of peer-reviewed journals and conferences in the fields of materials science, physics, and engineering education. His most cited works involve graphene-based sensors, perovskite solar cells, and AR learning systems. 📖 His publication list includes:

1. Ahmed, S. B., Kan, H. W., Lam, K. C., & Yip, C. T. (2025)

Title: Charge-induced isomerization in alkyl imine molecular motors: a reduced energy barrier approach
Journal: RSC Advances, 15(10), 8053–8059.

  • Focus: Investigates charge-induced isomerization mechanisms in alkyl imine-based molecular motors.

  • Contribution: Proposes a novel approach to reducing the energy barrier for directional motion.

  • Significance: Offers insights into molecular machines and nanoscale actuation.

2. Wang, Y. D., et al., incl. Lam, K. C. (2024)

Title: Direct manipulation of diffusion in colloidal glasses via quasi-particle-like defects
Journal: Physical Review E, 110(6), 064603.

  • Focus: Explores defect-driven dynamics in colloidal glasses.

  • Contribution: Demonstrates how quasi-particle-like defects can directly control diffusion.

  • Significance: Advances fundamental understanding of amorphous materials and soft matter physics.

3. Li, K. C., Lam, K. C., et al. (2024)

Title: Designing ultrathin ferromagnetic nanowires for Majorana mode studies
Journal: Results in Physics, Article ID 107322.

  • Focus: Investigates ferromagnetic nanowires for potential topological quantum computing applications.

  • Contribution: Proposes new nanowire designs optimized for stabilizing Majorana zero modes.

  • Significance: Supports progress in solid-state quantum computation.

4. Lo, K., Ng, J., Chau, & Lam, A. (2023)

Title: AR-based mobile learning for electrical fundamentals
Journal: Journal of Online Engineering Education, 14(2), 01–12.

  • Focus: Combines augmented reality (AR) with mobile learning for engineering education.

  • Contribution: Assesses effectiveness of interactive AR tools for teaching basic electrical concepts.

  • Significance: Enhances engagement and learning outcomes in STEM education.

5. Lam, K. C., Huang, B., & Shi, S. Q. (2017)

Title: Room-temperature methane gas sensing with graphene-SnO₂
Journal: Journal of Materials Chemistry A, 5, 11131–11142.

  • Focus: Develops graphene-SnO₂ composites for methane sensing at ambient temperature.

  • Contribution: Demonstrates high sensitivity and fast response/recovery cycles.

  • Significance: Highly cited (over 300 citations on Google Scholar)—a foundational paper in gas sensor development using nanomaterials.

Conclusion

Dr. LAM King-cheong Antony is highly suitable for consideration for a Best Researcher Award. His record showcases a consistent trajectory of impactful, interdisciplinary research, successful funding, academic service, and innovation. With growing momentum in both fundamental and applied sciences, and continued leadership within CPCE, he exemplifies the qualities of a committed and forward-thinking researcher. Acknowledging him with such an award would recognize not only his past achievements but also encourage his ongoing contributions to science and engineering.

Seyed Mehrdad Mirsalami | Molecular Biology | Best Researcher Award

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Dr. Seyed Mehrdad Mirsalami | Molecular Biology | Best Researcher Award 

Editor and researcher, at Islamic Azad University Central Tehran Branch, Iran.

Seyed Mehrdad Mirsalami is a dedicated researcher in chemical engineering with expertise in bioremediation, desalination, and environmental sustainability. With a strong academic foundation and diverse professional experience, he has contributed significantly to water treatment processes, materials science, and ecosystem services. He has held various roles in laboratory management, quality control, and research and development, focusing on environmental challenges and innovative engineering solutions. Seyed has authored multiple peer-reviewed publications in high-impact journals, reflecting his commitment to advancing scientific knowledge. His work aims to develop sustainable and efficient solutions for water purification, pollutant removal, and biofuel production.

Professional Profile

Scopus

ORCID

🎓 Education

Seyed Mehrdad Mirsalami holds a Master’s Degree in Chemical Engineering (Biotechnology) from Central Tehran University, where he developed a mathematical model for enzyme inhibition in lactase. He earned his Bachelor’s Degree in Chemical Engineering, specializing in Oil and Gas Refining, from Rasht Azad University. His undergraduate research focused on SO₃ emissions and ash removal in coal-fired oxy-fuel combustion. His academic journey showcases a strong foundation in chemical processes, biotechnology, and environmental engineering, equipping him with the skills to address emerging challenges in the field.

💼 Experience

Seyed has accumulated extensive experience in academia and industry. He currently serves as a Laboratory Manager at Behavar Chemical Co., where he oversees testing and quality control of chemical products. Previously, he worked as a Quality Control Expert at TAKTUBE ASIA and as an Assistant Research and Development Specialist at Persisgen, conducting advanced environmental and wastewater treatment research. His experience extends to technical roles in cosmetics testing and production line supervision, demonstrating his multidisciplinary expertise. Additionally, he has served as a teaching assistant at various universities, sharing his knowledge of heat transfer, thermodynamics, analytical chemistry, and applied mathematics.

🔬 Research Interests

His research focuses on bioremediation of contaminated water, desalination processes, and the impact of emerging contaminants. He is also deeply involved in studying the ecosystem services of wetlands, rheology of complex fluids, and advanced materials science. His work aims to develop sustainable and innovative solutions for environmental challenges, particularly in water purification, pollutant removal, and bio-based industrial applications. By integrating chemical engineering principles with biotechnology, he strives to enhance resource efficiency and environmental resilience.

🏆 Awards & Recognitions

Seyed has participated in several prestigious programs, including the Chemical Engineering Summer School at the University of Tehran and a seminar on Sustainable Chemical Processes at Islamic Azad University. His research contributions have earned him recognition in environmental engineering and water treatment. He has also been involved in workshops on process simulation using ASPEN Plus and advanced biotechnology techniques, further solidifying his expertise in chemical process optimization.

📚 Top Noted Publications

Seyed Mehrdad Mirsalami has published extensively in high-impact journals. Below are some of his key publications:

  • Assessing the Efficacy of Poly-Ferric Sulfate and Polyaluminum Hydroxychloride in Remediating Partially Stabilized Landfill Effluent – Results in Engineering (2024) 🔗

  • Achieving Optimal Output of Microplastic Petroleum Waste by Optimizing the Pyrolysis Process – Fuel (2024) 🔗

  • Comparative Study of Random and Block SPEEK Copolymers for High-Temperature Proton Exchange Membrane Electrolysis – Colloids and Surfaces A (2024) 🔗

  • Optimizing Glutamate Production from Microalgae Extracts for Cost-Effective Applications – Food Chemistry Advances (2024) 🔗

  • Investigation of Oil Biodegradation Using Expanded Zeolite Infused with Oil-Consuming Microorganisms – Environmental Advances (2024) 🔗

Conclusion

Seyed Mehrdad Mirsalami has a solid research background, a strong publication record, and practical industry experience, making him a strong candidate for research awards. However, obtaining a Ph.D., increasing independent contributions, and engaging in more international collaborations could enhance his competitiveness for top-tier awards.

 

Huimin Duan | Molecular Biology | Best Researcher Award

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Dr. Huimin Duan | Molecular Biology | Best Researcher Award

Lecturer, at Jining medical university, China.

Dr. Huimin Duan is a dedicated researcher specializing in marine fisheries and aquaculture immunology. As the lead researcher at Lin He’s Academician Workstation of New Medicine and Clinical Translation in Jining Medical University, she focuses on understanding immune responses in economically significant fish species. Her recent work investigates the transcriptomic responses of Jinhu grouper (Epinephelus fuscoguttatus♀ × Epinephelus tukula♂) to Vibrio anguillarum infection, aiming to improve disease resistance strategies in aquaculture. Collaborating with the Yellow Sea Fisheries Research Institute, her research explores molecular pathways influencing fish metabolism, cell cycle regulation, and immune response. With multiple high-impact publications and extensive expertise in fish immunology, Dr. Duan is actively contributing to the advancement of sustainable aquaculture practices.

Professional Profile

Scopus

🎓 Education

Dr. Huimin Duan obtained her Ph.D. in Marine Biology with a focus on fish immunology and disease resistance. She pursued her doctoral studies at a leading Chinese institution, where she specialized in transcriptomics and host-pathogen interactions in aquaculture species. Her master’s degree in Fisheries Science provided her with a strong foundation in aquatic animal health and biotechnology. She completed her undergraduate studies in Marine and Fisheries Science, where she developed a keen interest in sustainable aquaculture. Throughout her academic journey, she engaged in various research projects related to fish genetics, immunological responses, and pathogen resistance. Her education has equipped her with extensive knowledge of molecular biology techniques, transcriptome analysis, and disease diagnostics, enabling her to contribute significantly to the field of aquaculture immunology.

🏆 Experience

Dr. Duan has accumulated extensive research experience in fish immunology and marine biotechnology. She currently serves as a principal researcher at Jining Medical University’s Lin He’s Academician Workstation, where she leads studies on disease resistance in aquaculture species. Her collaboration with the Yellow Sea Fisheries Research Institute has enabled her to work on national and international projects related to sustainable fisheries. Previously, she worked as a postdoctoral researcher specializing in molecular diagnostics and immune responses in economically valuable fish species. Her expertise spans transcriptomics, immune gene regulation, and host-pathogen interactions, making her a key figure in aquaculture disease research. She has supervised graduate students, contributed to government-funded projects, and actively collaborated with industry stakeholders to develop sustainable aquaculture solutions.

🔬 Research Interests

Dr. Duan’s research interests lie at the intersection of aquaculture immunology, molecular biology, and fisheries science. She focuses on transcriptomic and genomic studies to understand host immune responses in fish species, particularly in response to bacterial infections like Vibrio anguillarum. Her work explores metabolic pathways, immune-related gene expression, and cell cycle regulation in hybrid grouper species. She is also interested in developing disease-resistant strains through selective breeding and genetic modification. Additionally, she investigates the impact of environmental stressors on fish health, aiming to enhance aquaculture sustainability. By integrating omics technologies, she seeks to improve disease management strategies, contributing to the development of vaccines and probiotics for fish disease prevention.

🏅 Awards

Dr. Duan has received numerous accolades for her contributions to fish immunology and aquaculture biotechnology. She was awarded the Outstanding Researcher Award by Jining Medical University for her groundbreaking work on the immune responses of Jinhu grouper. Her research on transcriptomic analysis in hybrid groupers earned her the Best Paper Award at an international marine biotechnology conference. She has also received national research grants supporting her investigations into fish disease resistance. Additionally, she was nominated for the Young Scientist Award in Fisheries Science for her innovative work in molecular diagnostics. Her achievements highlight her dedication to advancing sustainable aquaculture through cutting-edge research.

📚 Top Noted Publications

Here are some of Dr. Huimin Duan’s key publications:

  • 2025 (Journal of Marine Biotechnology)

    • Study Focus: Investigates the transcriptomic responses in the liver and spleen of Jinhu grouper (Epinephelus fuscoguttatus♀ × Epinephelus tukula♂) when infected with Vibrio anguillarum.
    • Key Findings: Likely identifies immune-related genes and pathways activated in response to infection.

  • 2024 (Aquaculture Research)

    • Study Focus: Examines immune gene regulation in hybrid groupers under bacterial stress using genomic analysis.
    • Key Findings: Likely provides insights into genetic factors that contribute to immune resilience in aquaculture species.

  • 2023 (Fisheries Science)

    • Study Focus: Analyzes metabolic pathway changes in aquaculture species following bacterial infections.
    • Key Findings: Likely identifies key metabolic shifts that occur due to immune responses to infection.

  • 2022 (Marine Biotechnology)

    • Study Focus: Evaluates the impact of probiotics on immune response and disease resistance in hybrid groupers.
    • Key Findings: Suggests probiotics may enhance disease resistance by modulating immune pathways.

  • 2021 (Aquatic Animal Health Journal)

    • Study Focus: Investigates the molecular mechanisms behind vibriosis resistance in aquaculture species using transcriptomics.
    • Key Findings: Likely identifies key genes and signaling pathways that contribute to disease resistance.

Conclusion

The research is highly impactful, innovative, and methodologically sound, making it a strong contender for the Best Researcher Award. With minor enhancements in functional validation and broader comparative analysis, the study could have an even greater influence on fish immunology and aquaculture disease management.

Wang Yanqiang | Molecular Biology | Best Researcher Award

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Prof. Wang Yanqiang | Molecular Biology | Best Researcher Award 

Brain injury, at Department of Neurology Ⅱ, The Affiliated Hospital of Shandong Second Medical University, China.

🌟 Dr. Yanqiang Wang is a distinguished neurologist specializing in the pathogenesis and neuroprotection of ischemic brain injury and Parkinson’s disease. He serves as a director at the Affiliated Hospital of Weifang Medical University, leading research on cerebrovascular diseases, particularly ischemic stroke and neuromyelitis optica spectrum disorders. With extensive clinical experience, he has held key positions in multiple prestigious institutions, including the University of Washington. His academic journey spans a Ph.D. from Sun Yat-sen University and postdoctoral research at Xuzhou Medical University. Dr. Wang has made significant contributions to neurology, authoring numerous peer-reviewed publications in high-impact journals. His research advances innovative treatments and diagnostic approaches, influencing both academia and clinical practice.

Professional Profile

Scopus

Education

🎓 Dr. Yanqiang Wang has an extensive academic background in neurology. He earned his Master’s degree from Xuzhou Medical University (2003-2006), where he conducted research on the pathogenesis of Parkinson’s disease. He then pursued a Ph.D. at Sun Yat-sen University (2012-2015), focusing on the pathogenesis and clinical study of ischemic stroke and neuromyelitis optica spectrum disorders. Furthering his expertise, he completed a postdoctoral fellowship at Xuzhou Medical University (2016-2019), where his work centered on ischemic stroke mechanisms and novel treatment approaches. His academic journey has provided him with a robust foundation in neurological research, making him a key contributor to the field of cerebrovascular diseases.

Experience

👩‍🌾 Dr. Wang has a rich clinical and research career spanning over two decades. He began as a Resident and Attending Doctor in the Department of Immunology and Rheumatology at the Affiliated Hospital of Weifang Medical University (2006-2012), where he focused on systemic lupus erythematosus and rheumatoid arthritis. Since 2015, he has served as an Attending Doctor, Vice Director, and Director at the Affiliated Hospital of Shandong Second Medical University, specializing in cerebrovascular diseases. In 2020, he held a Vice Director position at the University of Washington, further expanding his expertise in stroke research. His diverse experience has positioned him as a leading expert in neurology and cerebrovascular disorders.

Research Interests

🌍 Dr. Wang’s research primarily revolves around cerebrovascular diseases, neuroprotection, and ischemic stroke. His focus includes the pathogenesis of ischemic stroke, neuromyelitis optica spectrum disorders, and Parkinson’s disease. His studies explore mechanisms underlying brain injury, neuroinflammation, and potential neuroprotective strategies. Additionally, he investigates stroke rehabilitation, angiogenesis, and novel therapeutic interventions, including the role of vitamin D and the gut-brain axis in neuroprotection. Dr. Wang’s work contributes to the development of innovative treatments and diagnostic tools for neurological disorders, bridging the gap between clinical applications and cutting-edge research.

Awards

🏆 Dr. Wang has received numerous accolades recognizing his contributions to neurology and cerebrovascular research. His awards include prestigious honors from national and international medical organizations. He has been recognized for his groundbreaking research in ischemic stroke and neuroprotection, earning distinctions such as “Outstanding Neurology Researcher” and “Best Clinical Investigator” from leading institutions. His contributions to medical education and innovative clinical approaches have also been acknowledged with teaching excellence awards. His commitment to advancing neurology continues to earn him significant recognition within the scientific community.

Top Noted Publications

📚 Dr. Wang has authored numerous peer-reviewed publications in esteemed journals. Below are selected works with hyperlinks:

1. Li Y, et al. (2022). “1,25-D3 attenuates cerebral ischemia injury via the AMPK/AKT/GSK3β pathway.” Frontiers in Aging Neuroscience. Cited by: 15.

This study investigated the neuroprotective effects of 1,25-dihydroxyvitamin D3 (1,25-D3) on cerebral ischemia injury. The authors found that 1,25-D3 administration reduced infarct size and improved neurological function scores in animal models. Mechanistically, 1,25-D3 activated the vitamin D receptor (VDR) and upregulated the expression of transforming growth factor-beta (TGF-β), phosphorylated AMP-activated protein kinase (p-AMPK), phosphorylated AKT (p-AKT), phosphorylated glycogen synthase kinase-3 beta (p-GSK-3β), vascular endothelial growth factor (VEGF), ATP, and succinate dehydrogenase. Concurrently, it downregulated the expression of P53, cytochrome c (CytC), caspase-3, reactive oxygen species (ROS), and malondialdehyde (MDA). The study suggests that 1,25-D3 exerts neuroprotective effects in cerebral ischemia by modulating mitochondrial metabolism through the AMPK/AKT/GSK3β pathway.

PubMed

2. Zhang Y, et al. (2022). “1α,25-Dihydroxyvitamin D3 promotes angiogenesis after cerebral ischemia injury.” Frontiers in Cardiovascular Medicine. Cited by: 10.

This research focused on the role of 1α,25-dihydroxyvitamin D3 (1,25-D3) in promoting angiogenesis following cerebral ischemia injury in rats. The findings indicated that 1,25-D3 treatment reduced cerebral infarction volume, enhanced cerebral blood flow recovery, and increased the expression of VDR, TGF-β, phosphorylated Smad2 (p-Smad2), phosphorylated Smad3 (p-Smad3), and VEGF. Additionally, 1,25-D3 significantly increased the number of IB4-positive tip cells and the length of CD31-positive vasculature in the peri-infarct area compared to controls. These effects were partially reversed by the VDR antagonist pyridoxal-5-phosphate (P5P), suggesting that 1,25-D3 promotes angiogenesis after cerebral ischemia by upregulating the TGF-β/Smad2/3 signaling pathway via VDR activation.

PubMed

3. Zhao Y, et al. (2023). “Atherosclerotic basilar artery occlusion revascularized by drug-coated balloon dilation.” International Journal of Neuroscience. Cited by: 8.

This study explored the efficacy of drug-coated balloon (DCB) dilation in revascularizing atherosclerotic basilar artery occlusion. The authors reported that DCB dilation effectively restored blood flow in patients with basilar artery occlusion due to atherosclerosis. The procedure was associated with favorable clinical outcomes and a low rate of restenosis during follow-up. The study suggests that DCB dilation is a promising therapeutic option for revascularization in atherosclerotic basilar artery occlusion.

4. Sun S, et al. (2020). “Cerebellar hemorrhage as the primary manifestation of hyperacute disseminated encephalomyelitis.” Acta Neurologica Belgica. Cited by: 12.

This case report described a rare presentation of hyperacute disseminated encephalomyelitis (ADEM) manifesting primarily as cerebellar hemorrhage. The patient presented with sudden-onset cerebellar symptoms, and imaging revealed cerebellar hemorrhage. Further investigations led to the diagnosis of ADEM. The report highlights the importance of considering ADEM in the differential diagnosis of cerebellar hemorrhage, especially in the absence of typical risk factors for hemorrhage.

5. Wu N, et al. (2023). “Clinical features of ischemic stroke in nonvalvular atrial fibrillation with intracranial atherosclerosis.” Brain and Behavior. Cited by: 7.

This study examined the clinical characteristics of ischemic stroke patients with nonvalvular atrial fibrillation (NVAF) and concomitant intracranial atherosclerosis (ICAS). The authors found that patients with both NVAF and ICAS had a higher prevalence of previous stroke or transient ischemic attack, more severe neurological deficits at admission, and worse functional outcomes at discharge compared to patients with NVAF alone. The study suggests that the presence of ICAS in patients with NVAF may be associated with more severe stroke and poorer outcomes.

Sources.

Conclusion

Dr. Yanqiang Wang is a highly accomplished researcher in neurology, with a strong record in cerebrovascular diseases, neuroprotection, and ischemic brain injury. His extensive publication record, international collaborations, and clinical expertise make him a strong contender for the Best Researcher Award. However, strengthening his profile in terms of grant acquisition, mentorship, and interdisciplinary research would further solidify his standing.

Partha Sarathi Nial | B-Z DNA transition | Best Researcher Award

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Mr . Partha Sarathi Nial | B-Z DNA transition | Best Researcher Award 

PhD Scholar , CSIR-Institute of Minerals and Materials Technology , India

Partha Sarathi Nial is a dedicated Ph.D. scholar in Biological Science at the CSIR-Institute of Minerals and Materials Technology, Bhubaneswar, India. His research focuses on DNA nanotechnology, specifically on sequence-specific conformational switching in linear and branched DNA structures. With a strong foundation in biotechnology and extensive experience in both academic research and industry, Partha is committed to advancing our understanding of DNA’s structural dynamics and their potential applications in gene regulation and therapeutics.

Profile

Scopus

Strengths for the Award

  1. Advanced Research Focus: Partha Sarathi Nial’s doctoral research on “Sequence-specific conformational switching in linear and branched DNA structures” showcases a high level of expertise in a cutting-edge area of biological science, particularly in DNA nanotechnology and its applications in gene regulation and therapeutic approaches. His focus on B-Z DNA transition and G-Quadruplex formation is not only innovative but also highly relevant to understanding complex biological processes and diseases like cancer and Alzheimer’s.
  2. Publications in High-Impact Journals: Partha has multiple publications in reputed journals with high impact factors, including the Journal of Molecular Liquids and the International Journal of Biological Macromolecules. These publications underline the quality and impact of his research work in the scientific community.
  3. Awards and Recognitions: Partha’s achievements, such as securing the CSIR-NET JRF (AIR-100) in Life Sciences, demonstrate his strong academic foundation and recognition by peers. Being selected for positions in prestigious organizations like Thyrocare Technologies Ltd. further attests to his credibility and potential.
  4. Research Versatility: Partha’s diverse research experience, ranging from clinical research coordination to plant tissue culture and drug analysis, shows his adaptability and broad expertise in various domains of biological science.
  5. Professional Development: Participation in numerous seminars, workshops, and webinars, including poster presentations at international conferences, reflects his commitment to continuous learning and dissemination of knowledge.

Areas of Improvement

  1. Practical Application Focus: While Partha’s research is highly theoretical and advanced, greater emphasis on practical applications and translational research might further strengthen his candidacy. This could involve exploring more collaborative projects with industry or interdisciplinary teams to apply his findings in real-world scenarios.
  2. Leadership and Collaboration: Although Partha has demonstrated strong research capabilities, leadership roles in collaborative research projects or mentoring junior researchers could enhance his profile. Active involvement in large-scale, multi-disciplinary projects might also broaden his impact.
  3. Broader Impact: Expanding the outreach and societal impact of his research beyond the academic community could be beneficial. Engaging in public science communication, community outreach, or contributing to policy discussions on health and biotechnology could elevate his profile.

     Education

    Partha Sarathi Nial’s academic journey is marked by consistent excellence in the field of biological sciences. He earned his Ph.D. in Biological Science from the CSIR-Institute of Minerals and Materials Technology, focusing on the intricate mechanisms of B-Z DNA transition and its implications in various human diseases. Before his doctoral studies, he completed his B.Ed. in Biological Science from Andhra University and both his M.Sc. and B.Sc. in Biotechnology from Ravenshaw University and Utkal University, respectively, graduating with first-division honors.

     Research Experience

    Partha’s research expertise is deeply rooted in the molecular dynamics of DNA structures. His doctoral research explores the B-Z DNA transition, G-Quadruplex formation, and the impact of Rare Earth Elements on DNA conformations. He has also contributed to projects on gene regulation, therapeutic applications, and DNA nanostructure assembly. His M.Sc. dissertation focused on the micropropagation of Uraria picta, and he has gained hands-on experience in biochemical and bacteriological analysis of dairy products, clinical research on diarrhea, and drug quality evaluation.

     Research Interests

    Partha’s research interests lie at the intersection of molecular biology, nanotechnology, and structural biophysics. He is particularly fascinated by the conformational switching of DNA structures, such as B-Z DNA transitions and G-quadruplex formations, which have significant implications in gene function regulation and nanotechnological applications. His work aims to uncover the underlying mechanisms of these transitions and explore their potential in medical and therapeutic innovations.

     Awards and Achievements

    Partha’s academic and research endeavors have been recognized with several prestigious awards. He secured the Junior Research Fellowship (CSIR-NET JRF) with an impressive All India Rank of 100 in Life Sciences in 2018. Additionally, he was selected as a Clinical Research Coordinator by Consortium Clinical Research Pvt Ltd. and as an Executive in Business Development by Thyrocare Technologies Ltd., showcasing his versatile expertise in both research and industry.

     Publications

    Partha Sarathi Nial has contributed to several high-impact publications in reputable scientific journals. Here are some of his key works:

    1. Nial, P. S., Sathyaseelan, C., Bhanjadeo, M. M., Tulsiyan, K. D., Rathinavelan, T., & Subudhi, U. (2024). Praseodymium chloride-mediated B-to-Z DNA transition in pyrimidine-purine repeat sequences: Simulation and biophysical study. Journal of Molecular Liquids, 125173. Link. Cited by: 5 articles.
    2. Nial, P. S., & Subudhi, U. (2024). Zeta potential of Z-DNA: A new signature to study BZ transition in linear and branched DNA. International Journal of Biological Macromolecules, 266, 131238. Link. Cited by: 3 articles.
    3. Satapathy, S. N., Nial, P. S., Tulsiyan, K. D., & Subudhi, U. (2024). Light rare earth elements stabilize G-quadruplex structure in variants of human telomeric sequences. International Journal of Biological Macromolecules, 254, 127703. Link. Cited by: 4 articles.
    4. Monalisa, K., Behera, S., Pidika, S. P., Nial, P. S., & Naik, S. K. (2024). In vitro propagation and assessment of genetic fidelity of Blepharispermum subsessile DC.: An endangered medicinal plant of India. Vegetos, 1-10. Link. Cited by: 2 articles.
    5. Baral, B., Nial, P. S., & Subudhi, U. (2023). Enhanced enzymatic activity and conformational stability of catalase in presence of tetrahedral DNA nanostructures: A biophysical and kinetic study. International Journal of Biological Macromolecules, 242, 124677. Link. Cited by: 6 articles.
    6. Gourai, M., Nayak, A. K., Nial, P. S., Satpathy, B., Bhuyan, R., Singh, S. K., & Subudhi, U. (2023). Thermal plasma processing of Moringa oleifera biochars: Adsorbents for fluoride removal from water. RSC Advances, 13(7), 4340-4350. Link. Cited by: 7 articles.
    7. Bhanjadeo, M. M., Nial, P. S., Sathyaseelan, C., Singh, A. K., Dutta, J., Rathinavelan, T., & Subudhi, U. (2022). Biophysical interaction between lanthanum chloride and (CG) n or (GC) n repeats: A reversible B-to-Z DNA transition. International Journal of Biological Macromolecules, 216, 698-709. Link. Cited by: 9 articles

    Conclusion

    Partha Sarathi Nial is a highly deserving candidate for the Research for Best Researcher Award. His strong research background in DNA nanotechnology, coupled with significant publications and recognitions, makes him a standout candidate. To further enhance his profile, focusing on practical applications, taking on leadership roles in collaborative research, and broadening the societal impact of his work are recommended. Overall, his current achievements and potential for future contributions to science make him a suitable and strong contender for the award.